A5075298532- Diabetic Foot Ulcer Assessment and Management
- Wound Healing and Treatments
- Peripheral Artery Disease Management
- Skin Diseases and Diabetes
- Pressure Ulcer Prevention and Management
- Diagnosis and Treatment of Venous Diseases
- Botulinum Toxin and Related Neurological Disorders
- Pain Mechanisms and Treatments
- Muscle and Compartmental Disorders
- Pain Management and Treatment
- Neurological Disorders and Treatments
- Tendon Structure and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Dupuytren's Contracture and Treatments
- Myofascial pain diagnosis and treatment
- Musculoskeletal pain and rehabilitation
- Bone and Joint Diseases
- Neurological and metabolic disorders
- Dermatology and Skin Diseases
- Oral microbiology and periodontitis research
- Dermatological and Skeletal Disorders
- HIV, Drug Use, Sexual Risk
- Body Contouring and Surgery
- Lower Extremity Biomechanics and Pathologies
- Autoimmune Bullous Skin Diseases
Société Francophone du Diabète
2024
Sorbonne Université
2014-2023
Pitié-Salpêtrière Hospital
2014-2023
Assistance Publique – Hôpitaux de Paris
2008-2023
Fondation pour l’innovation en Cadiométabolisme et Nutrition
2023
Diabetes Australia
2004
Hôpital Saint-Vincent-de-Paul
1996
The diabetic Charcot foot syndrome is a serious and potentially limb-threatening lower-extremity complication of diabetes. First described in 1883, this enigmatic condition continues to challenge even the most experienced practitioners. Now considered an inflammatory syndrome, characterized by varying degrees bone joint disorganization secondary underlying neuropathy, trauma, perturbations metabolism. An international task force experts was convened American Diabetes Association Podiatric...
The primary objective was to characterize factors allowing the colonization of diabetic foot wounds by multidrug-resistant organisms (MDRO), and secondary evaluate influence MDRO colonization/infection on wound healing.In 180 patients admitted a specialized unit, microbiological specimens were taken admission. Potential risk for MDRO-positive examined using univariate multivariate analyses. Prospective follow-up data from 75 used time healing.Eighteen per cent admission positive MDRO. status...
To estimate the incidence, characteristics and potential causes of lower limb amputations in France.Admissions with were extracted from 2003 French national hospital discharge database, which includes major diagnoses procedures performed during admissions. For each patient, diabetes was defined by its record at least one admission or without amputation 2002-2003 databases.In 2003, 17 551 admissions recorded, involving 15 353 persons, included 7955 people diabetes. The crude incidence 378/100...
OBJECTIVE To compare the duration of healing foot ulcers with osteomyelitis in diabetic patients treated by medical treatment versus associated conservative orthopedic surgery. RESEARCH DESIGN AND METHODS We entered into study 67 who had a ulcer without ischemia requiring peripheral arterial reconstruction. Thirty-two were included first historic group from 1986 to 1993, antibiotic therapy, offloading, and wound care. September 1993 March 1995, same RESULTS The rate was 57% alone 78%...
OBJECTIVE—To compare the efficacy, safety, and compliance of a nonremovable fiberglass cast boot off-loading shoes in treatment diabetic plantar ulcers. RESEARCH DESIGN AND METHODS—Patients (n = 93) with noninfected, nonischemic ulcers were included this prospective nonrandomized study. Treatment used for longer standing deeper 42) half shoe or heel-relief other 51). We evaluated therapy, compliance, complications both groups. RESULTS—The healing rate was significantly higher than (81 vs....
To describe the rates of healing, major amputation and mortality after 12 months in patients with a new diabetic foot ulcer (DFU) their care French service (DFS).A prospective single-centre study including from March 2009 to December 2010. The length time minor amputation, rate inclusion were analysed using Kaplan-Meier method.Some 347 included (3% lost follow-up), median follow-up (IQR) 19 (12-24) months. mean (SD) age was 65±12 years, 68% male, duration 49 (19-120) days. Complications DFU...
To describe the rates of healing, major amputation and mortality after 12 months in patients with a new diabetic foot ulcer (DFU) their care French service (DFS).A prospective single-centre study including from March 2009 to December 2010. The length time minor amputation, rate inclusion were analysed using Kaplan-Meier method.Some 347 included (3% lost follow-up), median follow-up (IQR) 19 (12-24) months. mean (SD) age was 65±12 years, 68% male, duration 49 (19-120) days. Complications DFU...
To assess the relationship between site, ischaemia, neuropathy, bacterial infection, area, depth (SINBAD) score and major adverse foot events in patients with diabetes ulcers.For this retrospective ancillary study, (n = 537) followed for a diabetic ulcer (DFU) six French hospitals were included 1 February 2019 17 March 2019, 2020 2020. The SINBAD was assessed at inclusion. frequency of composite outcome consisting eight (MAFE) after 5-6 months follow-up: hospitalisation DFU, septic surgery,...
The objective of the study was to assess cost-effectiveness Vacuum Assisted Closure® (V.A.C.®) Therapy compared with advanced wound care (AWC) for treatment diabetic foot ulcers (DFUs) in France. A model intended reflect management DFUs updated French setting. Markov follows progression 1000 hypothetical patients over a 1-year period. populated French-specific data, obtained from published sources and clinical experts. analysis evaluated costs health outcomes, terms quality-adjusted...
The objective of this study was to evaluate the level healing chronic neuropathic plantar ulcers, using an irremovable windowed fibreglass cast boot, which is only opened after healing. A single-centre prospective a cohort 177 diabetic patients with ulcers carried out. duration 604 ± 808 days, mean surface area 4.6 6.5 cm(2) , depth 1.04 1.08 cm and volume 5.9 17.7 cm(3) . After 96 days wearing boot (min 9 max 664 median 68 days), reached 83.6%, although 29 did not heal (16.4%). compliance...
Objective Aggressive antidiabetic therapy and rapid glycemic control are associated with diabetic neuropathy. Here we investigated if this is also the case for Charcot neuroarthropathy. Research design methods HbA1c levels other relevant data were extracted from medical databases of 44 cases acute Results significantly declined 8.25% (67mmol/mol) [7.1%–9.4%](54-79mmol/mol), at -6 months (M-6), to 7.40%(54mmol/mol) [6.70%–8.03%] (50–64 mmol/mol) during six preceding diagnosis neuroarthropathy...
The pathophysiology of Charcot neuroarthropathy (CN) remains unclear. There are a number hypotheses but these not exclusive. In its clinical presentation, this complication intersects with the semiology diabetic-induced neuropathy, such as peripheral hypervascularization and appearance arteriovenous shunt. EPICHAR study is yet an unpublished cohort people living diabetes complicated by CN (in active or chronic phase). Based on findings study, aimed to investigate whether reduction in rate...