A5029963413- Diabetes Management and Research
- Diabetic Foot Ulcer Assessment and Management
- Diabetes Treatment and Management
- Wound Healing and Treatments
- Diabetes Management and Education
- Mobile Health and mHealth Applications
- Botulinum Toxin and Related Neurological Disorders
- Pressure Ulcer Prevention and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Peripheral Artery Disease Management
- Neurological and metabolic disorders
- Pain Mechanisms and Treatments
- Diabetes and associated disorders
- Metabolism, Diabetes, and Cancer
- Health, Medicine and Society
- Skin Diseases and Diabetes
- Neurological Disorders and Treatments
- Pancreatic function and diabetes
- Mesenchymal stem cell research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Dietary Effects on Health
- Medication Adherence and Compliance
- Pharmacology and Obesity Treatment
- Diagnosis and Treatment of Venous Diseases
- Bone Metabolism and Diseases
Centre Hospitalier Sud Francilien
2012-2024
Université d'Évry Val-d'Essonne
2022-2024
Université Paris-Saclay
2020-2024
Société Francophone du Diabète
2024
Université Paris Cité
2015-2023
Laboratoire de Biologie de l'Exercice pour la Performance et la Santé
2022
Laboratoire de Biologie et Pharmacologie Appliquée
2022
Inserm
2015-2020
Médecins Sans Frontières
2020
Centre de Recherche des Cordeliers
2019-2020
To demonstrate that Diabeo software enabling individualized insulin dose adjustments combined with telemedicine support significantly improves HbA(1c) in poorly controlled type 1 diabetic patients.In a six-month open-label parallel-group, multicenter study, adult patients (n = 180) diabetes (>1 year), on basal-bolus regimen (>6 months), ≥ 8%, were randomized to usual quarterly follow-up (G1), home use of smartphone recommending doses visits (G2), or the short teleconsultations every 2 weeks...
Background. The proportion of diabetic patients undergoing haemodialysis is rapidly increasing. Glucose control among such difficult to assess. We aimed evaluate the clinical performance a continuous glucose monitoring system (CGMS) in type 2 on chronic haemodialysis.
Two randomised controlled trials (RCTs) have previously shown that telemedical monitoring of diabetic foot ulcer (DFU) reduces the number visits to outpatient clinic, without losing treatment efficacy or increasing costs. Here we present results an open-label, trial designed investigate whether telemonitoring, provided by expert nurse (with extensive experience in DFU and trained remote monitoring), hospital stay associated costs for a patient with (TELEPIED trial).Eligible patients (n =...
TeleDiab-2 was a 13-month randomized controlled trial evaluating the efficacy and safety of two telemonitoring systems to optimize basal insulin (BI) initiation in subjects with inadequately type 2 diabetes (HbA1c, 7.5%-10%). A total 191 participants (mean age 58.7 years, mean HbA1c 8.9%) were into three groups: group 1(G1, standard care, n = 63), (G2, interactive voice response system, 64) 3 (G3, Diabeo-BI app software, 64). The proposed daily adjustments BI doses, order facilitate...
OBJECTIVE Hypertension in diabetes is characterized by abnormal sodium homeostasis, suggesting a particular role of natriuretic peptide pathway. Natriuretic peptides can affect blood pressure (BP) through their plasma concentrations, which are dependent on receptor activities. We thus assessed the association between nine NPR3 gene polymorphisms and BP levels patients with type 2 diabetes. RESEARCH DESIGN AND METHODS Nine single nucleotide (SNPs) tagging haplotype structure were genotyped...
We investigated the relationship between carbohydrate intake and postprandial blood glucose (BG) levels to determine most influential meal for type 2 diabetic subjects treated with basal insulin needing prandial insulin.Three-day BG profiles 37 subjects, A1C of 7.7%, sulfonylurea metformin, well titrated on glargine, were analyzed using a continuous monitoring system. Food from 680 meals was recorded quantified during monitoring.The median excursion (DeltaBG) higher at breakfast than lunch...
Background and Objectives: We describe a case of necrotic angiodermatitis. Materials Methods: used an intact fish skin graft to treat patient living with diabetes, which was complicated by end-stage renal failure arterial hypertension. The entire therapeutic procedure carried out in ambulatory care without requiring the hospitalization patient. Results: experienced marked reduction pain complete epithelization lesion after 10 weeks treatment. Conclusion: Our experience presents new approach
Diabetic foot ulcers are chronic, difficult to heal, and potentially life-threatening. Few medical devices have been studied in diabetic penetrating bone or tendon.
Diabetic foot ulcers (DFUs) are a real public health problem which carry high risk of amputation. The treatment DFUs is based on general management such as the infection, arterial disease, and offloading, but recent studies have shown that quality local covering can impact healing rate.
Objective Aggressive antidiabetic therapy and rapid glycemic control are associated with diabetic neuropathy. Here we investigated if this is also the case for Charcot neuroarthropathy. Research design methods HbA1c levels other relevant data were extracted from medical databases of 44 cases acute Results significantly declined 8.25% (67mmol/mol) [7.1%–9.4%](54-79mmol/mol), at -6 months (M-6), to 7.40%(54mmol/mol) [6.70%–8.03%] (50–64 mmol/mol) during six preceding diagnosis neuroarthropathy...
The pathophysiology of Charcot neuroarthropathy (CN) remains unclear. There are a number hypotheses but these not exclusive. In its clinical presentation, this complication intersects with the semiology diabetic-induced neuropathy, such as peripheral hypervascularization and appearance arteriovenous shunt. EPICHAR study is yet an unpublished cohort people living diabetes complicated by CN (in active or chronic phase). Based on findings study, aimed to investigate whether reduction in rate...
Diabetic macular edema (DME) is the main cause of visual loss associated with diabetes but any association between DME and cardiovascular events unclear.This study aims to describe possible in a multicenter cross-sectional patients type 2 diabetes.Two thousand eight hundred seven were recruited from nephrology clinical institutional centers participating DIAB NEPHROGENE focusing on diabetic complications. (presence/absence) retinopathy (DR) classification based ophthalmological report and/or...
Off-loading is essential for diabetic foot management, but remains understudied. The evaluation of using a new removable oRTHOsis in DIABetic (ORTHODIAB) trial aims to evaluate the efficacy device "Orthèse Diabète" healing foot.ORTHODIAB French multi-centre randomized, open label trial, with blinded end points by an adjudication committee according Prospective Randomized Open Blinded End-point. Main endpoints are adjudicated based on analysis photographs. Orthèse Diabète off-loading orthosis...
The rate of recurrence for diabetic foot ulcer (DFU) is 50% at 2 years Armstrong DG, 2017. International recommendations call regular monitoring to prevent DFU recurrence. We aim investigate the relation between post-healing follow-up and rates. study will begin in November 2021 end April 2022; final results are scheduled December 2022. purpose evaluate benefit multidisciplinary healed patients two annual consultations its impact on wound
The correction and control of chronic hyperglycemia are the management goals patients living with diabetes. Chronic is main factor inducing diabetes-related complications. However, in certain situations, rapid intense can paradoxically favor onset microvascular complications.In this case report, we describe a 25-year-old woman type 1 diabetes since age 9 years. Her was unstable but without During an unplanned pregnancy, her intensely managed hyperglycemia. over following 2 years, she...