RaySearch Americas Inc. (NY) has introduced a commercial Monte Carlo dose algorithm (RS-MC) for routine clinical use in proton spot scanning. In this report, we provide validation of against phantom measurements and simulations the GATE software package. We also compared performance RayStation analytical (RS-PBA) RS-MC algorithm. A beam model (G-MC) scanning gantry at our center was implemented The validated water used benchmarking RS-MC. Validation performed by measuring depth doses...

In this report, we present the commissioning and validation results for a commercial proton pencil beam scanning RayStation treatment planning system.The data requirements are (1) integrated depth dose curves, (2) spot profiles, (3) absolute dose/monitor unit calibration, (4) virtual source position. An 8-cm parallel plate chamber was used to measure curves by composed of single in water phantom. The profiles were measured at 5 different planes using 2-dimensional scintillation detector....

Purpose: To investigate the dosimetric accuracy of sliding window gated IMRT compared with static treatment, using varying dose rates.Materials and methods: This study measured changes in output diode array response changing rate, verified precision motion table, distribution film diodes at two depths rate.During 4DCT (4 Dimensional Computed Tomography), patient's respiratory signals target were recorded imported to XY4D simulation table SUN NUCLEAR Corporation simulate respiration tumour...

Patient-specific intensity-modulated radiotherapy (IMRT) verifications require an accurate two-dimensional dosimeter that is not labor-intensive. We assessed the precision and reproducibility of film calibrations over time, measured elemental composition film, intermittency effect, dosimetric accuracy calibrated Kodak EDR2 for single-beam in a solid water phantom full-plan Rexolite® phantom. Repeated measurements sensitometric curve single experiment yielded overall uncertainties dose 2.1%...

Stereotactic radiosurgery (SRS) and fractionated stereotactic radiotherapy (FSRT) programs to treat brain tumors were implemented when we first acquired the Brainlab Novalis system in 2003. Two years later, started an extra-cranial radio-ablation or more appropriately a body radiation therapy (SBRT) program using image-guided at The Methodist Hospital Houston, Texas. We hereby summarize our initial experience with this delivering SBRT total of 80 patients during year clinical implementation,...

We report the results of a precise test charge symmetry in scattering polarized neutrons from protons at laboratory bombarding energy 183 MeV. The observable sensitive to is difference between analyzing powers associated with neutron spin [${\mathit{A}}_{\mathit{n}}$(\ensuremath{\theta})] and proton [${\mathit{A}}_{\mathit{p}}$(\ensuremath{\theta})]. Systematic errors experimental ambiguities measurement this are extensively discussed. Our result for...

Theoretical calculations have shown that proton therapy can reduce the incidence of radiation-induced secondary malignant neoplasms (SMN) compared with photon for patients prostate cancer. However, uncertainties associated SMN risk had not been assessed. The objective this study was to quantify in projected risks cancer following contemporary and radiotherapies We performed a rigorous propagation errors several sensitivity tests estimate uncertainty ratio relative (RRR) due largest...

With the emergence of more complex and novel proton delivery techniques, there is a need for quality assurance tools with high spatiotemporal resolution to conveniently measure spatial temporal properties beam. In this context, scintillation-based dosimeters, if synchronized radiation beam corrected ionization quenching, are appealing.To develop high-speed scintillation imaging system characterization verification therapy beams on pulse-by-pulse basis.A 30 cm × 5 block BC-408 plastic...

The population of excited states Li and Be nuclei emitted in the $^{14}$N+Ag reaction E/A=35 MeV has been measured. results confirm a recently measured disagreement between temperature determined from slopes energy distributions that obtained state populations. Recent models which were developed to explain discrepancy are discussed.

Laser wakefield acceleration (LWFA) technology has evolved to where it should be evaluated for its potential as a future competitor existing that produces electron and x‐ray beams. The purpose of the present work is investigate dosimetric properties an beam achievable using LWFA technology, document necessary improvements make radiotherapy application viable. This paper first qualitatively reviews fundamental principles describes design 30 cm accelerator chamber containing gas target....

Recently, a commercial treatment planning system (TPS) has implemented aperture collimators for PBS dose calculations which can serve to reduce lateral penumbra. This study characterized the variation in magnitude of penumbra collimated and un-collimated fields versus parameters air gap, depth, range shifter thickness. Comparisons were performed homogenous geometry between measured data made by TPS. Beam-specific target volumes generated optimized various thicknesses gaps. Lateral (80%-20%...

With the advancement of data‐intensive technologies, such as image‐guided radiation therapy (IGRT) and intensity‐modulated (IMRT), amount complexity data to be transferred between clinical subsystems have increased beyond reach manual checking. As a result, unintended treatment deviations (e.g., dose errors) may occur if system is not closely monitored by comprehensive transfer quality management program (QM). This report summarizes findings recommendations from task group (TG) on assurance...

In this study, we compared the amount of lung tissue irradiated when respiratory gating was imposed during expiration with inspiration. Our hypothesis that spared increased as inspiration increased. Computed tomography (CT) image data sets were acquired for 10 patients diagnosed primary bronchogenic carcinoma. Data free breathing, breath‐holds at 0% tidal volume and 100% volume, and, possible, deep corresponding to approximately 60% vital capacity. Two treatment plans developed on basis each...

We performed 858 two‐dimensional (2D) patient‐specific intensity modulated radiotherapy verifications over a period of . Multifield, composite treatment plans were measured in phantom using calibrated Kodak EDR2 film and compared with the calculated dose extracted from two planning systems. This research summarizes our findings normalized agreement test (NAT) index percent pixels failing gamma as metrics to represent between computed distributions. An in‐house comparison software package was...

High energy electrons and positrons observed in medium nucleus-nucleus collisions are shown to be primarily due the external conversion of high gamma rays. The reaction $^{14}\mathrm{N}$+Cu was studied at E/A=40 MeV, a magnetic spectrograph used with specially constructed multiwire proportional counter plus Cerenkov detectors. A stopping target yield 1.8\ifmmode\pm\else\textpm\fi{}0.6\ifmmode\times\else\texttimes\fi{}${10}^{\mathrm{\ensuremath{-}}6}$ photons ${E}_{\ensuremath{\gamma}}$>25...

Current protocols for the measurement of proton dose focus on measurements under reference conditions; methods measuring patient‐specific conditions have not been standardized. In particular, it is unclear whether in fields can be determined more reliably with or without presence range compensator. The aim this study was to quantitatively assess reliability two per monitor unit values small‐field treatment portals: one compensator and A Monte Carlo model Proton Therapy Center‐Houston...

Neutron production is of concern for proton therapy, especially passive scattering beam delivery methods. The levels neutron dose equivalent vary significantly with system design and treatment parameters. purpose this study was to examine per therapeutic (H/D) around the Mevion S250 therapy system, a novel systems. benchmark comparisons between measurement simulation were found be within factor 2 most cases. H/D values evaluated as function various results showed that, at standard reference...