A5065147774- Helicobacter pylori-related gastroenterology studies
- Eosinophilic Esophagitis
- Gastroesophageal reflux and treatments
- Celiac Disease Research and Management
- Gastrointestinal disorders and treatments
- Microscopic Colitis
- Folate and B Vitamins Research
- Erythropoietin and Anemia Treatment
- Iron Metabolism and Disorders
- Microbial Community Ecology and Physiology
- Gastric Cancer Management and Outcomes
- Potassium and Related Disorders
- Galectins and Cancer Biology
- Mycobacterium research and diagnosis
- Genomics and Phylogenetic Studies
Sapienza University of Rome
2022-2024
Corpus-restricted atrophic gastritis is a chronic inflammatory disorder leading to possible development of type 1 neuroendocrine tumors (T1gNET), intraepithelial neoplasia (IEN), and gastric cancer (GC). We aimed assess occurrence predictors neoplastic lesions in patients with corpus-restricted at long-term follow-up.A prospective single-center cohort adhering endoscopic-histological surveillance was considered. Follow-up gastroscopies were scheduled according the management epithelial...
INTRODUCTION: To describe the clinical features and risk of developing gastric tumors in patients with autoimmune gastritis (AIG). METHODS: This was a retrospective, longitudinal, multicenter study conducted at 8 Italian tertiary referral centers. We retrieved data from all histologically proven AIG. Differences between Helicobacter pylori -exposed vs H. -naive anti-parietal cell antibody (PCA)-positive PCA-negative were investigated. The rate adenocarcinoma type 1 neuroendocrine neoplasm...
Gender differences and microbiota are gaining increasing attention. This study aimed to assess gender in gastric bacterial between subjects with healthy stomachs those autoimmune atrophic gastritis. was a post hoc analysis of 52 undergoing gastroscopy for dyspepsia (57.7% stomach, 42.3% gastritis). Gastric biopsies were obtained histopathology genomic DNA extraction. assessed by sequencing the hypervariable regions 16SrRNA gene. The profile at phylum level reported as being relative...
Corpus Atrophic Gastritis (CAG) is characterised by iron malabsorption leading to deficiency anaemia (IDA), which rarely responds oral therapy. Ferric carboxymaltose (FCM), shown be a safe and effective intravenous therapy in other diseases, has not been investigated yet CAG. Thus, we aimed assess the safety efficacy of FCM CAG-related IDA. A retrospective study on 91 patients identified CAG as only cause IDA treated with FCM. Twenty-three were excluded for incomplete follow-up. Sixty-eight...
Abstract Background and study aims In autoimmune atrophic gastritis (AAG), associated with intestinal (IM) and/or pseudopyloric metaplasia (PPM), endoscopic surveillance is recommended for gastric cancer risk mainly linked to IM. Endoscopic Grading of Gastric Intestinal Metaplasia (EGGIM) reliably identifies IM, but has not been assessed in AAG. We aimed assess the performance EGGIM (index test) versus histology (reference corpus IM Patients methods This was a cross-sectional 210 AAG...
Background: Recent advances in microbiome sequencing techniques have provided new insights into the role of on human health with potential diagnostic implications. However, these developments are often hampered by presence a large amount DNA interfering analysis bacterial content. Nowadays, extensive scientific literature focuses eukaryotic depletion methods, which successfully remove host studies, even if precise assessment impact is missing. Methods: Here, we investigated saponin-based...
Iron-deficiency anemia in the elderly may be due to numerous gastrointestinal conditions. Anemia is frequent celiac disease (CD); however, use of routine duodenal biopsies, independently age or serology, debated. To determine diagnostic yield biopsies adult and patients with no bleeding anemia, a cross-sectional study analyzing 7968 gastroscopies (2017−2020) was performed; 744 were for 275 excluded (GI without biopsies). Of 469 included patients, clinical, endoscopic, histological features...
Aims Corpus Atrophic Gastritis (CAG) is characterized by inflammation and oxyntic gland loss. CAG defined as autoimmune when sparing antrum Helicobacter pylori (Hp)-related (multifocal) involved. Possible antral healing has been supposed. Since crucial for gastritis diagnosis implies a lowering of OLGA-OLGIM risk scores gastric cancer, we aimed to analyse histology at long-term follow-up (FU) in patients with concomitant involvement.
Aims In Corpus atrophic gastritis(CAG) the occurrence of gastric-neoplastic-lesions(GNL),as type I neuroendocrine tumors(T1gNET),intraepithelial-neoplasia(IEN),and gastric-cancer(GC) is still debated.We aimed to assess and predictors GNL at long-term follow-up(FU).
Aims Autoimmune atrophic gastritis (AAG) is a chronic inflammatory condition of the corpus sparing antrum supposed to be at risk for gastric type I neuroendocrine tumors (T1gNET), but relatively low adenocarcinoma (ADK) compared higher OLGA/OLGIM-stages. Prospective studies quantifying neoplastic in AAG are lacking. The current study aimed prospectively assess ADK, dysplasia and T1gNET incidence patients long-term follow-up.
We would like to thank Greenaway et al. [...].