- Gestational Trophoblastic Disease Studies
- RNA modifications and cancer
- Cancer Mechanisms and Therapy
- Chromatin Remodeling and Cancer
- Genomics, phytochemicals, and oxidative stress
- Social Media and Politics
- Circular RNAs in diseases
- Congenital Heart Disease Studies
- MicroRNA in disease regulation
- Epigenetics and DNA Methylation
- Heat shock proteins research
- Cell death mechanisms and regulation
- Biochemical effects in animals
- Mechanisms of cancer metastasis
- Cardiac Arrhythmias and Treatments
- Metastasis and carcinoma case studies
- Cancer-related molecular mechanisms research
- Prenatal Screening and Diagnostics
- Neuroendocrine Tumor Research Advances
- Cancer-related Molecular Pathways
- Liver Disease Diagnosis and Treatment
- Cardiac pacing and defibrillation studies
- Lung Cancer Research Studies
Hainan Medical University
2017-2024
Women's Hospital, School of Medicine, Zhejiang University
2019-2022
Deutsches Herzzentrum der Charité
2002
Guangdong Medical College
2000
Circular RNAs (circRNAs) represent a newly identified class of non‑coding RNA molecules, which interfere with gene transcription by adsorbing microRNAs (miRNAs). CircRNAs serve important roles in disease development and have the potential to as novel biomarkers for clinical diagnosis. However, role circRNAs occurrence gastric cancer (GC) remains unclear. In present study, expression profiles were compared between GC adjacent normal tissues using circRNA microarray, following quantitative...
Ras-related C3 botulinum toxin substrate 1 (RAC1) is a member of the Rho family small GTPases. Recent studies have reported that RAC1 serves an important role in colon cancer cell proliferation. The present study aimed to investigate effects knockdown on proliferation, cycle progression and apoptosis cells. Lentivirus‑mediated short hairpin RNA (shRNA) was used expression lines, apoptosis, were evaluated by MTT assays flow cytometry. differences mRNAs identified between RAC1-knockdown cells...
Choriocarcinoma is one of the most aggressive gestational trophoblastic neoplasias (GTN). Methotrexate (MTX) resistance main cause treatment failure in choriocarcinoma. However, mechanism MTX choriocarcinoma poorly known. This study aims to explore function Lectin galactoside-binding soluble 3 binding protein (LGALS3BP) MTX-resistance cells. Gradual dose escalation was used establish MTX-resistant cells (JAR-MTX and JEG3-MTX cell lines). RNA-sequencing differentially expressed genes....
Bei Frühgeborenen (FG) mit kongenitalem kompletten atrioventrikulären Block (AVB III°) ist die Implantation eines permanenten Herzschrittmachers (HSM) aufgrund der Größenverhältnisse erst ab einem Körpergewicht von ca. 2000 g möglich. Wir berichten über Erfahrungen einer Schrittmacher-Therapie bei deutlich kleineren FG 832 g.