A5086091845- Fungal Infections and Studies
- Plant Pathogens and Fungal Diseases
- Antifungal resistance and susceptibility
- COVID-19 Clinical Research Studies
- Mycorrhizal Fungi and Plant Interactions
- COVID-19 and Mental Health
- Nail Diseases and Treatments
- SARS-CoV-2 and COVID-19 Research
- Actinomycetales infections and treatment
Northern Arizona University
2020-2023
Marshfield Clinic
2020
Coccidioides immitis and C. posadasii are soil dwelling dimorphic fungi found in North South America. Inhalation of aerosolized asexual conidia can result asymptomatic, acute, or chronic respiratory infection. In the U.S. there approximately 350,000 new infections per year. The genus is only known fungal pathogen to make specialized parasitic spherules, which contain endospores that released into host upon spherule rupture. molecular determinants involved this key step infection remain...
Blastomycosis is endemic in Wisconsin with Blastomyces dermatitidis and B. gilchristii responsible for infections. Urine antigen testing a non-invasive diagnostic method blastomycosis up to 93% test sensitivity. However, the test's sensitivity has not been evaluated relationship infections.We aimed assess physician use of urine assay its infections retrospective study. Culture confirmed clinical cases from 2008-2016 were identified within Marshfield Clinic Health System (MCHS) UW Hospital...
Abstract Severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, is the causative agent of disease 2019, COVID-19, and current COVID-19 pandemic. Even as more vaccine candidates are released, treatment options critically needed. Here, we investigated use Minnelide, a water soluble pro-drug with anti-inflammatory properties, for COVID-19. To do this, k18-hACE2 mice were infected SARS-CoV-2 or given PBS control intranasally. The next day either treated daily low dose (0.0025mg/day) high...