A5086172863- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Electrospun Nanofibers in Biomedical Applications
- Dental materials and restorations
- biodegradable polymer synthesis and properties
- Additive Manufacturing and 3D Printing Technologies
- Calcium Carbonate Crystallization and Inhibition
- Orthodontics and Dentofacial Orthopedics
- 3D Printing in Biomedical Research
- Parvovirus B19 Infection Studies
- Infective Endocarditis Diagnosis and Management
- Cytomegalovirus and herpesvirus research
- Polymer Surface Interaction Studies
- Orthopaedic implants and arthroplasty
- Materials Engineering and Processing
- Myasthenia Gravis and Thymoma
- Orthopedic Infections and Treatments
- Injection Molding Process and Properties
- Retinal Diseases and Treatments
- Magnesium Oxide Properties and Applications
- Pericarditis and Cardiac Tamponade
- Herpesvirus Infections and Treatments
Hospital do Desterro
2023
University of Aveiro
2018-2023
Abstract Yttria‐stabilized zirconia (YSZ) scaffolds with a planned macroporosity fraction of about 70% were fabricated by Robocasting from inks high solid loadings. The effects solids loading and the concentrations processing additives on flow behavior starting suspensions viscoelastic properties resulting investigated aiming at optimizing printing process. shear thinning containing 45‒48 vol% dispersant varying within 0.2‒0.8 wt% could be well described four‐parameter Cross model....
Bi-phasic calcium phosphates (BCPs) are considered prominent candidate materials for the fabrication of bone graft substitutes. Currently, supplemental cation-doping is suggested as a powerful path to boost biofunctionality, however, there still lack knowledge on structural role such substituents in BCPs, which turn, could influence intensity and extent biological effects. In this work, pure Mg- Sr-doped BCP scaffolds were fabricated by robocasting from hydrothermally synthesized powders,...
This study investigates the osteogenic differentiation of umbilical-cord-derived human mesenchymal stromal cells (hUC-MSCs) on biphasic calcium phosphate (BCP) scaffolds derived from cuttlefish bone doped with metal ions and coated polymers. First, in vitro cytocompatibility undoped ion-doped (Sr2+, Mg2+ and/or Zn2+) BCP was evaluated for 72 h using Live/Dead staining viability assays. From these tests, most promising composition found to be scaffold strontium (Sr2+), magnesium (Mg2+) zinc...
Abstract Bioactive glass powders synthesized by solgel are usually porous and exhibit high specific surface areas, conferring them poor ability for scaffolds fabrication using colloidal processing approaches. The difficulties associated with of have hindered so far the 3‐D robocasting. This research paper investigates importance calcination temperature ( CT ) balls to powder ratio BPR used upon wet milling on maximum achievable solid loading in aqueous media. effects , flow behavior...
The present study deals with the development of multifunctional biphasic calcium phosphate (BCP) scaffolds coated biopolymers-poly(ε-caprolactone) (PCL) or poly(ester urea) (PEU)-loaded an antibiotic drug, Rifampicin (RFP). amounts RFP incorporated into PCL and PEU-coated were 0.55 ± 0.04 0.45 0.02 wt%, respectively. in vitro drug release profiles buffered saline over 6 days characterized by a burst within first 8h, followed sustained release. Korsmeyer-Peppas model showed that was...
Abstract This work is a proof of concept for making load bearing implants with osseointegration and bone bonding ability. Yttria‐stabilized zirconia (YSZ) scaffolds percentage macro porosity about 70% were fabricated by robocasting. Although maximum solids volume fraction 50 vol.% could be achieved, the 3D‐printing process revealed to more reliable when using inks 48 solids. The sintered porous structures exhibited an average compressive strength ~236 MPa. After some preliminary coating...
The combination of calcium phosphates with bioactive glasses (BG) has received an increased interest in the field bone tissue engineering. In present work, biphasic (BCP) obtained by hydrothermal transformation cuttlefish (CB) were coated a Sr-, Mg- and Zn-doped sol-gel derived BG. scaffolds characterized X-ray diffraction, Fourier transform infrared spectroscopy scanning electron microscopy. initial CB structure was maintained after (HT) scaffold functionalization did not jeopardize...
Abstract In this paper, we present a new series of alkali‐free bioactive glasses (BG) based on FastOs ® composition (38.49 SiO 2 – 36.07 CaO 19.24 MgO 5.61 P O 5 0.59 CaF , expressed in mol %), which was modified by partially replacing silicon dioxide network‐former with boron trioxide network‐former, utilizing calcium oxide as charge compensator. The main objective study to obtain family suitable for the fabrication glass fibers. BGs were prepared melt quenching technique and their...
The combination of calcium phosphates (CaP) with bioactive glasses (BG) has received an increased interest in the field bone tissue engineering. In present work, biphasic (BCP) obtained by hydrothermal transformation (HT) cuttlefish (CB) were coated a Sr-, Mg- and Zn-doped sol-gel derived BG. scaffolds characterized X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) scanning electron microscopy (SEM). initial CB structure was maintained after HT scaffold...
Background: Cytomegalovirus is the most common cause of congenital infections worldwide. Screening all newborns in first 2 weeks life only way to detect cases infection, allowing monitoring children with asymptomatic infection at birth and early intervention. Aim: In this multicenter study, we aimed evaluate feasibility using a saliva pool strategy for mass screening 7 Portuguese hospitals, estimate current prevalence these hospitals. Methods: A total 7033 were screened between June 2020...
Bone is a dynamic tissue with the capacity of repair and regeneration in specific conditions. Nevertheless, due to increased incidence bone disorders, need grafts has been growing over past decades development an ideal graft optimal properties remains clinical challenge. This review addresses (morphology, composition their capacity) puts main focus on potential strategies for developing materials. It describes requirements designing suitable scaffold material, types materials (polymers,...