A5070026877- Gastrointestinal disorders and treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Essential Oils and Antimicrobial Activity
- Genomics, phytochemicals, and oxidative stress
- Helicobacter pylori-related gastroenterology studies
- Esophageal and GI Pathology
- Phytochemicals and Antioxidant Activities
- Antibiotic Resistance in Bacteria
- Gallbladder and Bile Duct Disorders
- Aquaculture disease management and microbiota
- Vibrio bacteria research studies
- Insect Pest Control Strategies
- Tracheal and airway disorders
- Gastric Cancer Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Bacteriophages and microbial interactions
- Phytochemistry and Biological Activities
- Gastrointestinal Tumor Research and Treatment
- Moringa oleifera research and applications
- Pancreatitis Pathology and Treatment
- Psidium guajava Extracts and Applications
- Science and Education Research
- Bacterial biofilms and quorum sensing
- Education and Digital Technologies
- Health and Medical Education
University of Minho
2009-2023
University of Trás-os-Montes and Alto Douro
2011-2023
New York State Psychiatric Institute
2023
New York Psychoanalytic Society and Institute
2023
AC Camargo Hospital
2022
Instituto do Câncer do Estado de São Paulo
2022
University of Coimbra
2021
Universidade do Porto
2016-2019
Hospital Clínico Universitario de Caracas
2014-2018
Instituto Politécnico de Santarém
2018
The purpose of the present study was to evaluate in vitro antibacterial effects different classes important and common dietary phytochemicals (5 simple phenolics - tyrosol, gallic acid, caffeic ferulic chlorogenic acid; chalcone phloridzin; flavan-3-ol (-) epicatechin; seco-iridoid oleuropein glucoside; 3 glucosinolate hydrolysis products allylisothiocyanate, benzylisothiocyanate 2-phenylethylisothiocyanate) against Escherichia coli, Pseudomonas aeruginosa, Listeria monocytogenes...
Purified isothiocyanates from cruciferous plants (Brassicacea, Syn. Cruciferae) were evaluated against 15 isolates of methicillin-resistant S. aureus isolated diabetic foot-ulcer patients aiming the study potential usage allyl-isothiocyanate, benzyl-isothiocyanate and 2-phenylethyl-isothiocyanate this important bacteria. Disc diffusion minimum inhibitory concentration methods used to access antimicrobial activity. The index (Ia) rate (Ra) antibacterial activity for each compound calculated....
The potential risk of occurrence new diseases associated with the trade live animals is well known.However, little importance still given to problematic dissemination resistance genes that pass along animal trade.In this study we aimed isolate Aeromonas spp.strains from water and skin ornamental fish test their antibiotics.The samples were collected a national importer, intent obtaining collection strains.The identification strains was made by gyrB rpoD gene sequencing.A total 288 grouped in...
Pterospartum tridentatum and Mentha pulegium are largely used in Portuguese folk medicine to treat several human disorders inflammatory processes but without any consistent evidence for those beneficial pointed properties. Thus, the aim of current work is evaluate its benefits phytochemicals related A distinct polyphenol profile between P. M. was found. Taxifolin, myricetin, ginestin, ginestein, ginestein derivatives, biochanin A-glucoside, were identified , whilst luteolin-7-rutinoside,...
The "One Health" concept recognizes that human health and animal are interdependent bound to the of ecosystem in which they (co)exist. This interconnection favors transmission bacteria other infectious agents as well flow genetic elements containing antibiotic resistance genes. problem is worsened when pathogenic have ability establish biofilms. Therefore, it important understand characteristics behaviour microorganisms both planktonic biofilms states from most diverse environmental niches...
is one of the most notorious pathogens for its ability to adapt, colonize, and proliferate in different habitats through a multitude acquired virulence factors. Its presence affects food-processing industry causes food poisoning, being also major economic burden food, agriculture, health sectors. Bacteriophages are emerging as an appealing strategy mitigate bacterial pathogens, including specific
The emergence of new diseases and the resurgence several infections that were controlled in past, associated with recent increase bacterial resistance have created necessity for more studies towards to development antimicrobials treatment strategies. aim present study was evaluate vitro synergy between different classes important glucosinolates hydrolysis products-isothiocyanates antibiotics (gentamycin vancomycin), against pathogenic bacteria: Escherichia coli, Enterococcus faecalis,...
The aim of this study was to evaluate the bioactivity flavonoids extracted from sweet-cherry stems which are often used by a traditional system medicine treat gastro-intestinal and urinary tract infections but lacking any consistent scientific evidence; moreover information about class phenolics, their content potential such material is very scarce. Thus, in context, we have set research evaluated profile phenolics through conventional (70ºC 20 min) ultrasound assisted extraction (40 kHz,...
Evidence has shown that hospital surfaces are one of the major vehicles nosocomial infections caused by drug-resistant pathogens. Smart surface coatings presenting multiple antimicrobial activity mechanisms have emerged as an advanced approach to safely prevent this type infection. In work, industrial waterborne polyurethane varnish formulations containing for first time cationic polymeric biocides (SPBs) combined with photosensitizer curcumin were developed afford contact-active and...
The present study deals with the development of multifunctional biphasic calcium phosphate (BCP) scaffolds coated biopolymers-poly(ε-caprolactone) (PCL) or poly(ester urea) (PEU)-loaded an antibiotic drug, Rifampicin (RFP). amounts RFP incorporated into PCL and PEU-coated were 0.55 ± 0.04 0.45 0.02 wt%, respectively. in vitro drug release profiles buffered saline over 6 days characterized by a burst within first 8h, followed sustained release. Korsmeyer-Peppas model showed that was...
The aim of this study was to evaluate the effects various glucosinolate-derived hydrolysis products (HP) as antibacterial compounds against Enterobacteriaceae and Enterococcaceae isolated from intestinal segments healthy pigs collected directly slaughter-houses in North Portugal. Using a previously described disk-diffusion bioassay, all HP were tested at six different doses (0.015, 0.15, 0.75, 1.5, 3.0, 15.0 μmoles) dimethyl-sulfoxide (DMSO), with exception sulforaphane (SFN), which not...
AeromonAs are Gram-negative, facultative-anaerobic, non-sporeforming, glucose-fermenting, oxidase-and catalase-positive rods (Martin-Carnahan and Joseph 2005).Apart from fish, which widely reported hosts for Aeromonads, insects, crustaceans, reptiles, birds mammals were also found to harbour Aeromonas species, both in healthy disease state (Pearson others 2000, Turutoglu 2005, Evangelista-Barreto 2006, Ceylan 2009).An increase resistance levels of the genus, particularly β-lactam...
Head-restrained behavioral experiments in mice allow neuroscientists to observe neural circuit activity with high-resolution electrophysiological and optical imaging tools while delivering precise sensory stimuli a behaving animal. Recently, human rodent studies using virtual reality (VR) environments have shown VR be an important tool for uncovering the mechanisms underlying spatial learning hippocampus cortex, due extremely control over parameters such as contextual cues. Setting up...
With this study we intend to evaluate the effects of 8 different glucosinolate hydrolysis products including isothiocyanates as antibacterial compounds against Aeromonadaceae, isolated from intestinal segments pigs collected directly slaughter-houses in North Portugal. Four Aeromonas species, A. allosaccharophila, hydrophila, media and veronii were identified. Using disc-diffusion bioassay all tested at 6 doses (0.015, 0.15, 0.75, 1.5 3.0 µmoles) dimethyl-sulfoxide (DMSO). Antibiotic...