A5103064244- Peripheral Neuropathies and Disorders
- Hereditary Neurological Disorders
- Poisoning and overdose treatments
- Cardiac Arrest and Resuscitation
- Monoclonal and Polyclonal Antibodies Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Appendicitis Diagnosis and Management
- Heparin-Induced Thrombocytopenia and Thrombosis
- Multiple Myeloma Research and Treatments
- Radiation Dose and Imaging
- Ultrasound in Clinical Applications
- Sepsis Diagnosis and Treatment
- Dysphagia Assessment and Management
- Multiple Sclerosis Research Studies
- Esophageal and GI Pathology
- Botulinum Toxin and Related Neurological Disorders
- Amyotrophic Lateral Sclerosis Research
- Ocular Surface and Contact Lens
- Data-Driven Disease Surveillance
- Myasthenia Gravis and Thymoma
- Foreign Body Medical Cases
- Glioma Diagnosis and Treatment
- Cell Adhesion Molecules Research
- Thermal Regulation in Medicine
- Biosimilars and Bioanalytical Methods
Ajou University
2008-2025
Seoul National University
2012-2024
Seoul National University Hospital
2020-2024
New Generation University College
2023
Boramae Medical Center
2019-2021
Ajou University Hospital
2017
To investigate the safety, feasibility and preliminary efficacy of low-frequency repetitive transcranial magnetic stimulation (rTMS) over cerebellum in ataxic patients with acute posterior circulation stroke.Randomized, double-blind, sham-controlled pilot study.Thirty-two stroke were randomized to real (n = 22) sham 10) rTMS groups.Patients received 5 15-min sessions 1 Hz cerebellar consecutive days. Compliance adverse events for checked. The 10-m walk test (10MWT) Berg Balance Scale (BBS)...
Background Optic neuritis (ON) prognosis is influenced by various factors including attack severity, underlying aetiologies, treatments and consequences of previous episodes. This study, conducted on a large cohort first ON episodes, aimed to identify unique prognostic for each subtype, while excluding any potential influence from pre-existing sequelae. Methods Patients experiencing their with complete aquaporin-4 (AQP4) myelin oligodendrocyte glycoprotein (MOG) antibody testing, clinical...
The amplitude, timing, and determinants of improvement with available treatments are uncertain in chronic inflammatory demyelinating polyneuropathy (CIDP). Our primary objective was to quantify categorized outcomes routine care.
Emerging evidence supports artificial intelligence-enhanced electrocardiogram (AI-ECG) for detecting acute myocardial infarction (AMI), but real-world validation is needed. The aim of this study was to evaluate the performance AI-ECG in AMI emergency department (ED). Rule-Out Myocardial Infarction using Artificial intelligence Electrocardiogram analysis (ROMIAE) a prospective cohort conducted Republic Korea from March 2022 October 2023, involving 18 university-level teaching hospitals. Adult...
Unlike other immune-mediated neuropathies, anti-myelin-associated glycoprotein (MAG) neuropathy is often refractory to immunotherapy. It necessary compare the relative efficacies of various immunotherapies and develop objective biomarkers in order optimize its clinical management.
Neuromyelitis optica spectrum disorder (NMOSD) causes relapsing inflammatory attacks in the central nervous system, leading to disability. As rituximab, a B-lymphocyte-depleting monoclonal antibody, is an effective preventing NMOSD relapses, we hypothesised that earlier initiation of rituximab can also reduce long-term disability patients with NMOSD.This multicentre retrospective study involving 19 South Korean referral centres included aquaporin-4 antibodies receiving treatment. Factors...
To compare the diagnostic performance of computed tomography (CT) and Alvarado score to determine whether patient age sex influence use CT for diagnosing acute appendicitis.We retrospectively reviewed scans medical records 372 patients who presented with right lower quadrant pain underwent rule out appendicitis.The population was classified by its on CT. Receiver operating characteristic analysis used calculate both modalities.The overall area under receiver curves 0.965 (highly accurate)...
To investigate predictive factors for percutaneous endoscopic gastrostomy (PEG) removal, thereby minimizing unnecessary PEG insertion in post-stroke dysphagia.Retrospective cohort study.A total of 49 patients who undertook tube dysphagia.Patients were divided into a removal group (n = 8) and sustaining 41) depending on the presence tube. Patients' demographic data, nutritional status, Charlson's Comorbidity Index (CCI), video-fluoroscopic swallowing study findings at time compared between 2...
The purpose of this article was to evaluate the usefulness ultralow-dose chest CT as an initial imaging study for evaluation sharp fish bone esophageal foreign body (FB).A total 57 subjects who underwent were included in retrospective study. All had a history ingestion and symptoms FB. data reconstructed twice, once with filtered back projection (FBP) iterative reconstruction, three observers reviewed images independently. ROC analysis used diagnostic performance CT. Intraclass correlation...
Abstract Scrambler therapy is a noninvasive electroanalgesia technique designed to remodulate the pain system. Despite growing evidence of its efficacy in patients with neuropathic pain, little known about clinical factors associated treatment outcome. We conducted prospective, open-label, single-arm trial assess and safety scrambler chronic various etiologies. A post-hoc analysis was performed investigate whether cluster Neuropathic Pain Symptom Inventory (NPSI) profiles could identify...
Abstract Background Despite standard‐of‐care treatment, therapeutic outcomes in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) are often incomplete. We aimed to evaluate the impact of clinical and factors on long‐term disability CIDP, from cohorts Korea UK. Methods conducted a retrospective multicenter cohort study 144 patients with CIDP. Baseline characteristics treatment data were collected, was assessed using Overall Neuropathy Limitation Scale (ONLS) for UK cohort,...
We aimed to compare the diagnostic performance and inter-observer consistency between low dose chest CT (LDCT) standard (SDCT) in patients with blunt trauma. A total of 69 who met criteria indicative trauma (77% male; age range, 16–85) were enrolled. All underwent LDCT without intravenous (IV) contrast SDCT IV using parameters as following: LDCT, 40 mAs automatic tube current modulation (ATCM) 100 kVp (BMI <25, n = 51) or 120 (BMI>25, 18); SDCT, 180 ATCM kVp. Transverse, coronal, sagittal...
Physician assessment of hydration status is one the most important factors in management dehydration pediatric emergency department (ED). Overestimating may lead to overtreatment with intravenous fluids or unnecessary hospitalization, whereas underestimation delayed therapy and aggravation symptoms. Various methods estimate have been proposed, including use physical findings, body weight, laboratory results. These are subjective, invasive, inappropriate for application ED. A few studies...
Cerebral hemodynamic and metabolic changes may occur during the rewarming phase of targeted temperature management in post cardiac arrest patients. Yet, studies on different rates patient outcomes are limited. This study aimed to investigate patients who were rewarmed with after 24 hours hypothermia association these neurologic outcomes.This retrospectively investigated treated 0.15°C/hr 0.25°C/hr. The rate poor (cerebral performance category score, 3 5) was investigated.A total 71 analyzed...
Summary Objective: In an effort to identify and characterize the environmental factors that affect number of patients with acute diarrheal (AD) syndrome, we developed tested two regional surveillance models including holiday weather information in addition visitor records, at emergency medical facilities Seoul metropolitan area Korea. Methods: With 1,328,686 department records from National Emergency Department Information system (NEDIS) information, seasonal ARIMA were constructed: (1) The...
Autoimmune nodopathy (AN) is a rare condition marked by autoantibodies that target specific proteins located within the node of Ranvier or paranodes. This disorder distinctly different from chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), with AN patients displaying unique clinical symptoms include acute subacute onset, primarily distal muscle weakness, sensory ataxia, tremors, and significant increase in cerebrospinal fluid protein levels. Certain antibodies are linked to...
Autoimmune nodopathy (AN) is a rare condition marked by autoantibodies that target specific proteins located within the node of Ranvier or paranodes. This disorder distinctly different from chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), with AN patients displaying unique clinical symptoms include acute subacute onset, primarily distal muscle weakness, sensory ataxia, tremors, and significant increase in cerebrospinal fluid protein levels. Certain antibodies are linked to...
Despite treatment, a considerable proportion of patients with Guillain-Barré syndrome (GBS) experience poor recovery, highlighting therapeutic need. There is lack evidence that treatment timing affects recovery. This study aims to investigate the effects intravenous immunoglobulin (IVIg) on disability and speed recovery in GBS.
Autoimmune nodopathy (AN) is a rare immune-mediated neuropathy characterized by autoantibodies against nodal or paranodal proteins. Patients with AN generally respond poorly to immunoglobulin therapy, and as newly defined condition, there are currently no established treatment guidelines. Although rituximab shows potential therapeutic option, its high cost, limited availability, the need for infusion monitoring hinder use first-line in many countries. In this report, we identified antibodies...