- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Alcohol Consumption and Health Effects
- Environmental Quality and Pollution
- Liver Disease Diagnosis and Treatment
- Calcium Carbonate Crystallization and Inhibition
- Water Resources and Sustainability
- Land Use and Ecosystem Services
- Remote Sensing and Land Use
- Crystallography and molecular interactions
- Phytochemicals and Antioxidant Activities
- Topic Modeling
- Crystal structures of chemical compounds
- Organoselenium and organotellurium chemistry
- Selenium in Biological Systems
- Photonic and Optical Devices
- Diet, Metabolism, and Disease
- Enzyme function and inhibition
- Environmental Impact and Sustainability
- Multimodal Machine Learning Applications
- Sulfur Compounds in Biology
- Microbial Applications in Construction Materials
- Sustainability and Ecological Systems Analysis
- Bone Tissue Engineering Materials
- Acne and Rosacea Treatments and Effects
Central South University
2024-2025
Huazhong University of Science and Technology
2005-2024
University of California, Los Angeles
2023-2024
University of Science and Technology Beijing
2022-2024
China Agricultural University
2021-2024
Tongji Hospital
2023-2024
Nanjing University of Posts and Telecommunications
2024
Chongqing University of Technology
2024
Hainan University
2024
Heilongjiang Bayi Agricultural University
2024
Nonalcoholic fatty liver disease (NAFLD) has become one of the public health problems globally. The occurrence NAFLD is usually accompanied by a series chronic metabolic diseases, with prevalence rate 25.24% among adults worldwide. Therefore, seriously affects quality life in patients and causes large economic burden. It been reported that puerarin function lowering serum lipids, but due to complexity NAFLD, specific mechanism action not clarified. aim this study was evaluate preventive or...
Tilapia produces a large number of by-products during processing, which contain potentially flavorful peptides. The application PyRx software enabled batch molecular docking andscreening 16 potential salty peptides from 189 identified in the enzymaticdigestion tilapia by-products. According to sensory analysis, all werepredominantly with threshold 0.256 - 0.379 mmol/L some sournessand astringency, among HLDDALR had highest intensity, followedby VIEPLDIGDDKVR, FPGIPDHL, and DFKSPDDPSRH. I...
Biomineralization induced by microorganisms has become a hot spot in the field of carbonate sedimentology; however, mechanisms involved still need to be explored. In this study, bacterium Bacillus subtilis J2 (GenBank MG575432) was used induce precipitation calcium minerals at Mg/Ca molar ratios 0, 3, 6, 9, and 12. bacteria released ammonia increase pH, but only made pH 8.25. Carbonic anhydrase also produced catalyze hydration carbon dioxide, process bicarbonate ions that not increased...
Astragalus, a medical and edible plant in China, shows several bioactive properties. However, the role of astragalus attenuating alcoholic liver disease (ALD) is less clear. The objective this project to investigate improving effect saponins (AS) polysaccharides (AP), which are two primary constituents on hepatic injury induced by alcohol, potential mechanisms action. Different doses AS (50 100 mg/kg bw) AP (300 600 were orally given alcohol-treated mice for four weeks. results demonstrated...
Ferulic acid could promote uric excretion in the kidneys and intestine to ameliorate high-fructose/fat diet-induced hyperuricemia alleviate its associated renal impairment intestinal microbiota disorder.
As a thiol-dependent enzyme, thioredoxin reductase (TrxR) is promising antibacterial drug target. Ebselen, an organo-selenium with well-characterized toxicology and pharmacology, was recently reported to have potent activity against Staphylococcus aureus. In this paper, we demonstrated that ebselen has strong bactericidal multidrug-resistant (MDR) S. aureus based on taking TrxR as major target disruption of the redox microenvironment. Further, topical therapeutic efficacy for staphylococcal...
The systemic inflammatory response index (SIRI), a novel inflammation maker, has proven to be associated with prognostic outcomes in various diseases. However, few studies have been conducted assessing how SIRI may influence of patients on peritoneal dialysis (PD). Herein, we assessed the predictive value mortality all-cause mortality, including cardiovascular disease (CVD) PD patients.
Removal of calcium and magnesium ions through biomineralization induced by bacteria has been proven to be an effective environmentally friendly method improve water quality, but the process mechanism are far from fully understood. In this study, a newly isolated probiotic Bacillus licheniformis SRB2 (GenBank: KM884945.1) was used induce bio-precipitation at various Mg/Ca molar ratios (0, 6, 8, 10, 12) in medium with 30 g L−1 sodium chloride. Due increasing pH HCO3− CO32− concentrations...
The halophilic bacterium Halomonas smyrnensis from a modern salt lake used in experiments to induce biomineralization has resulted the precipitation of monohydrocalcite and other carbonate minerals. In this study, WMS-3 (GenBank:MH425323) strain was identified based on 16S rDNA homology comparison, then cultured mediums with 3% NaCl concentration at different Mg/Ca molar ratios 0, 2, 5, 7, 9. growth curve bacteria, pH values, NH4+ concentration, HCO3− CO32− carbonic anhydrase (CA) activity,...
Abstract Ebselen (EbSe), an organo-selenium compound with well-characterized toxicology and pharmacology, exhibited potent antibacterial activity against glutathione (GSH)-positive bacteria when combined silver ions (Ag+). In this paper, the strong bactericidal of EbSe–Ag+ multidrug-resistant (MDR) Acinetobacter baumannii has been confirmed, its efficacy was mainly based on inhibition thioredoxin reductase (TrxR) depletion total GSH amount. Moreover, therapeutic effect urinary tract...
Although biomineralization of minerals induced by microorganisms has been widely reported, the mechanisms and characteristics biominerals precipitated needs to be studied further. In this study, Staphylococcus warneri YXY2, a moderate halophile, was used induce precipitation carbonate at various Mg/Ca molar ratios. To investigate mechanism, growth curve, pH changes, ammonia test, concentration bicarbonate ions, activity carbonic anhydrase (CA) alkaline phosphatase (ALP) were determined....