- Thyroid and Parathyroid Surgery
- Adrenal and Paraganglionic Tumors
- Parathyroid Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Voice and Speech Disorders
- Growth Hormone and Insulin-like Growth Factors
- Pituitary Gland Disorders and Treatments
- Dental Research and COVID-19
- Genetic Syndromes and Imprinting
- Medical Imaging and Pathology Studies
- BRCA gene mutations in cancer
- Tracheal and airway disorders
- Vitamin D Research Studies
- Airway Management and Intubation Techniques
- Dental Radiography and Imaging
- Dysphagia Assessment and Management
- Radiomics and Machine Learning in Medical Imaging
- Hormonal Regulation and Hypertension
- Cancer, Hypoxia, and Metabolism
- S100 Proteins and Annexins
- Artificial Intelligence in Healthcare and Education
- Neuroendocrine Tumor Research Advances
- Meningioma and schwannoma management
- Cancer Genomics and Diagnostics
- Neuroblastoma Research and Treatments
National Medical and Surgical Center named after N.I. Pirogov
2017-2024
Ministry of Health of the Russian Federation
2018-2020
Background: Molecular genetic events are among the numerous factors affecting clinical course of papillary thyroid carcinoma (PTC). Recent studies have demonstrated that aberrant expression miRNA, as well different thyroid-related genes, correlate with aggressive PTC and unfavorable treatment outcome, which opens up new avenues for using them in personalization strategy patients PTC. In present work, our goal was to assess applicability molecular markers preoperative diagnosis variants...
Molecular genetic events are among the numerous factors affecting clinical course of papillary thyroid carcinoma (PTC). Recent studies have demonstrated that aberrant expression miRNA, as well different thyroid-related genes, correlate with aggressive PTC and unfavorable treatment outcomes, which opens up new avenues for using them in personalization strategy patients PTC. In present work, our goal was to assess applicability molecular markers preoperative diagnosis variants cancer. The...
To analyze risk factors and prognosis of voice disorders after surgical treatment thyroid parathyroid diseases.There were 1272 patients who operated in the endocrine surgery department for period from January 1, 2016 to April 30, 2017. We studied incidence VF paresis, paralysis, persistent dysphonia as clinical outcomes. Potential have be analyzed sex age patients, BMI, diagnosis, technique, volume, experience surgeon assistant, use intraoperative neuromonitoring, etc. RESULTS: Significant...
Ectopic secretion of ACTH from non-pituitary tumors, referred to as ectopic syndrome (EAS), accounts for about 10–20% Cushing’s (CS). hormone-secreting pheochromocytomas (Pheo) are rare. The first publication association between pheochromocytoma and by Roux is dated 1955. Pheochromocytoma represents a rare cause hypercortisolism, accounting less than 5 % while 1 accompanied syndrome.We reporting 4 cases ACTH-secreting presenting syndrome. Data patients were analysed. There women 50 63 years...
Purpose. To study a possibility of performance and diagnostic accuracy ultrasonography (US) larynx in identification motility disorders VF (vocal folds) comparison with the laryngoscope which is traditionally applied for this purpose.Materials methods. According to objectives study, two patient groups were formed. In first group patients (n = 466) we studied acceptability ultrasonografy discriminate various laryngeal structures. second 432) evaluated point detection vocal muscles...
A well-known feature of primary hyperparathyroidism (PHPT) is possible ectopic localization parathyroid adenoma that can significantly complicate diagnostic process. Ectopia in the aortic window extremely rare and accounts only 1% adenomas mediastinum 0.24% among all adenomas. Combination multinodular toxic goiter with a variant ectopia makes this observation very valuable from scientific practical point view.Известной особенностью первичного гиперпаратиреоза является возможность...
Thyroid cancer is the 9th most common in world. The five-year survival rate for this disease over 98%. However, some patients there are cases of rapidly progressive treatment-resistant that cannot be differed from poor-invasive by routine methods. Liquid biopsy could one methods to solve problem. This procedure consists analysis tumor derivatives (in particular, circulating DNA) body fluids. hotspot mutations and patterns epigenetic regulation, which usual neoplasms with a certain genotype,...
To determine optimal surgical approach in patients with adrenal tumors.Overall experience of treatment tumors comprises over 300 procedures including 152 minimally invasive surgeries.We have presented the advantages and relative disadvantages various technologies which are useful to be considered most surgery these patients.There no serious contradictions use existing methods tumors. Minimally along conventional (open) interventions significantly enlarged rational choice for neoplasms...
To optimize diagnosis and surgical treatment of patients with primary hyperparathyroidism.Retrospective comparative analysis included 444 who were treated at the specialized department endocrine surgery Pirogov National Medical Surgical Center in 2012-2017. Archival materials electronic databases clinic applied.It was developed algorithm which may be used most for minimally invasive parathyroidectomy. Minimally reduces risk complications is associated reliable efficacy good cosmetic...
В статье представлен обзор современных тенденций в мининвазивной хирургии щитовидной и околощитовидных железах. Обзор включает анализ инновационных видеоэндоскопических операций при новообразованиях желез.