A5000302242- Nanoparticles: synthesis and applications
- Advanced Nanomaterials in Catalysis
- Carbon and Quantum Dots Applications
- Analytical chemistry methods development
- Gold and Silver Nanoparticles Synthesis and Applications
- Electrochemical sensors and biosensors
- Heavy metals in environment
- Geochemistry and Elemental Analysis
- Moringa oleifera research and applications
- Medicinal Plants and Neuroprotection
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Radioactive element chemistry and processing
- Pneumonia and Respiratory Infections
- Amphibian and Reptile Biology
- Species Distribution and Climate Change
- Mycobacterium research and diagnosis
- Cancer Mechanisms and Therapy
- Occupational and environmental lung diseases
- Insect Pest Control Strategies
- Extracellular vesicles in disease
- Nanocluster Synthesis and Applications
- Mercury impact and mitigation studies
- Electrostatic Discharge in Electronics
- Microbial Inactivation Methods
- Acute Myocardial Infarction Research
Chinese Academy of Sciences
2021-2025
Institute of High Energy Physics
2021-2025
University of Hong Kong
2021-2025
Sun Yat-sen University
2024-2025
University of Chinese Academy of Sciences
2021-2025
Nanjing Forestry University
2023
Shanghai University of Sport
2022
Songjiang District Central Hospital
2019
Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible lung disease with high mortality limited treatment options. While single-dose bleomycin-induced models are commonly used to investigate the pathogenesis of IPF, they fail adequately replicate complex pathological features in human patients, thereby hindering comprehensive investigations. Previous studies utilizing repetitive bleomycin injections have demonstrated closer resemblance IPF pathology; however, time-...
Life is inherently heterogeneous, and visualizing this heterogeneity in the spatial distribution of biometals offers valuable insights into various biological processes. While biometal mapping provides superior resolution compared to other bioanalytical techniques, it alone cannot fully explain functional roles health disease. In study, we introduced a novel method using specially designed sample grids facilitate beam-, X-ray-, ion-beam-based imaging on same tissue section. This innovative...
The development of nanotechnology has transformed many cutting-edge studies related to single-molecule analysis into nanoparticle (NP) detection with a single-NP sensitivity and ultrahigh resolution. While laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) been successful in quantifying tracking NPs, its quantitative calibration remains major challenge due the lack suitable standards uncertain matrix effects. Herein, we frame new approach prepare via precise synthesis...
Abstract Spatial patterns of body size are associated with environmental factors like temperature, seasonality, precipitation, resources, and altitude, among the most relevant. Latitudinal have been extensively studied. Studies on altitudinal gradients size, however, relatively few. Besides, it is still unclear whether there variation in relationship between species, or correlations within different altitudes. China provides a good opportunity to assess because entire terrain changes from...
As one of the most widely used nanomaterials, CeO2 nanoparticles (NPs) might be released into aquatic environment. In this paper, interaction NPs and Ce3+ ions (0~10 mg/L) with duckweed (Lemna minor L.) was investigated. significantly inhibited root elongation at concentrations higher than 0.1 mg/L, while inhibition threshold 0.02 mg/L. At high doses, both reduced photosynthetic pigment contents led to cell death induced stomatal deformation, but toxicity greater that same concentration....
Nanoparticles (NPs) suspension is thermodynamically unstable, agglomeration and sedimentation may occur after introducing NPs into a physiological solution, which in turn affects their recognition uptake by cells. In this work, rod-like gold (AuNRs) with uniform morphology size were synthesized to study the impact of bovine serum albumin (BSA) pre-coating on cellular AuNRs. A comparison using horizontal vertical cell culture configurations was performed reveal effect AuNRs at single-cell...
Investigating the ternary relationship among nanoparticles (NPs), their immediate molecular environment, and test organisms rather than direct interaction between pristine NPs has been thrust into mainstream of nanotoxicological research. Diverging from previous work that predominantly centered on surrounding molecules affecting toxicity by modulating nanoproperties, this study unveiled a novel dimension: altering bacterial susceptibility to NPs, consequently impacting outcomes nanobio...
Lung squamous cell carcinoma (LUSC) accounts for approximately 25% to 30% of lung cancers, but largely no targeted therapy is available against it, calling identification new oncogenes in LUSC growth therapeutic targets.In this study, REL was identified through a screening that are highly amplified human LUSC.Its expression associated with poor prognosis patients.Furthermore, knockdown c-Rel lines lead significant decrease proliferation and migration.Mechanistically, suppressed NFκB pathway...
Quantitatively studying the biodistribution and transformation of nanomaterials is great importance for nanotoxicological evaluation. Recently, laser ablation inductively coupled plasma mass spectrometry has been employed to distinguish nanoparticles (NPs) with their dissolved ions in biological samples. The principle proposal based on a hypothesis that intact NPs sampled by will generate discrete sharp pulses signals ICP-MS measurement, being totally different from continuous, relatively...
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This meta-analysis of cohort studies was performed to investigate the effect cross-country skiing on atrial fibrillation risk. Databases PubMed, EMBASE, Web Science, and China National Knowledge Internet were searched from inception dates April 25, 2021. Two reviewers independently extracted data assessed quality studies. A using random-effects model estimate overall relative risks (RR) incidence 95% confidence intervals (CIs) for individuals with skiers general population. After screening...
CeO2 nanoparticles (NPs) are applied in many fields and will inevitably be released into the aquatic environment. In this paper, we investigated toxicity of NPs their ionic counterpart Ce3+ ions to duckweed (Lemna minor L.) explored potential mechanisms. Both them at high doses could significantly inhibit growth duckweed, induce oxidative damage lead cell death. SEM images showed changes stomatal morphology fronds. TEM observations demonstrated adsorption internalization materials treated...
A compact fast Marx generator has been designed, built and tested. The is made of 10 inductively isolated capacitor stages. All the capacitors switches are placed in a stainless steel about 400 mm diameter 500 high. cylinder filled with SF <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sub> N xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> gas so as to enhance insulation ability. output voltage achieve 300 kV repetition 10Hz. risetime...