A5012204720- Schizophrenia research and treatment
- Functional Brain Connectivity Studies
- Bipolar Disorder and Treatment
- Cannabis and Cannabinoid Research
- Tryptophan and brain disorders
- Mental Health Research Topics
- Neurobiology of Language and Bilingualism
- Memory and Neural Mechanisms
- Mental Health and Psychiatry
- Attention Deficit Hyperactivity Disorder
- Mental Health Treatment and Access
- Stress Responses and Cortisol
- Neuroscience and Music Perception
- Social Sciences and Policies
- Health, Environment, Cognitive Aging
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Vitamin D Research Studies
- Herpesvirus Infections and Treatments
- Child and Adolescent Psychosocial and Emotional Development
- Dementia and Cognitive Impairment Research
- Diet and metabolism studies
- Toxoplasma gondii Research Studies
- Educational Innovations and Technology
- Child Abuse and Trauma
- Neuroscience and Neuropharmacology Research
National Institute of Mental Health
2012-2024
Charles University
2013-2023
National Institute of Public Health
2022
National University of General Sarmiento
2022
ORCID
2021
Marqués de Valdecilla University Hospital
2017
Karlovac University of Applied Sciences
2015
University Psychiatric Hospital
2011
Vall d'Hebron Hospital Universitari
2011
Objective Toxoplasmosis is a lifelong parasitic disease that appears to be associated schizophrenia. However, no distinguishing attributes in T oxoplasma‐ infected schizophrenia patients have been described as yet. Method We searched for differences symptom profile, cognitive performance and treatment response between 194 oxoplasma ‐free 57 (22.7%) ‐infected treated P rague sychiatric C entre 2000 2010. Results Infected non‐infected differed severity of symptoms ( = 0.032) measured with the...
Abstract This opinion article analyzes the implementation of 2022 Study Plan in México, identifying barriers that hinder its consolidation. Some mentioned are: unfinished principals, lack resources and adequate infrastructure, resistance to change on part managers teachers, difficulties training professional development technological access information, ambiguities evaluation process. At same time, some strategies alternative solutions are proposed, better management proper use resources,...
The character of cognitive deficit in schizophrenia is not clear due the heterogeneity research results. In heterogeneous conditions, cluster solution allows classification individuals based on profiles. Our aim was to examine profiles first-episode spectrum disorder (FES) subjects analysis, and correlate these with clinical variables resting state brain connectivity, as measured magnetic resonance imaging. A total 67 FES were assessed a neuropsychological test battery variables. results...
Cognitive deficit is considered to be a characteristic feature of schizophrenia disorder. A similar cognitive dysfunction was demonstrated in animal models schizophrenia. However, the poor comparability methods used assess cognition animals and humans could responsible for low predictive validity current models. In order spatial abilities compare our results with data obtained models, we designed virtual analog Morris water maze (MWM), Four Goals Navigation (vFGN) task.Twenty-nine patients...
The association between cannabis use and positive symptoms in schizophrenia spectrum disorders is well documented, especially via meta-analyses. Yet, findings are inconsistent regarding negative symptoms, while other dimensions such as disorganization, depression, excitement, have not been investigated. In addition, meta-analyses aggregated data discarding important confounding variables which a source of bias.PubMed, ScienceDirect PsycINFO were used to search for publications from inception...
Objectives: Deficit in visuospatial functions can influence both simple and complex daily life activities. Despite the fact that deficit was reported schizophrenia, research on as an independent entity is limited. Our study aims to elucidate impact of comparison with verbal global functioning quality first psychotic episode schizophrenia spectrum disorder (FES). The significance clinical symptoms antipsychotic medication also studied. Methods: Thirty-six FES patients a matched group healthy...
In this study, we aimed to determine whether childhood trauma moderated the relationship between inflammation and cognitive functioning in persons with first-episode schizophrenia spectrum disorders (SSDs). We included data from 92 individuals who participated nationwide Early-Stage Schizophrenia Outcome study. These completed Childhood Trauma Questionnaire, provided a fasting blood sample for high-sensitivity C-reactive protein analysis, underwent extensive neuropsychological testing. The...
Acute and transient psychotic disorder (ATPD) is characterized by acute onset of symptoms early recovery. Contrastingly, schizophrenia (SZ) a chronic mental impaired functioning including deficit in cognition. In SZ, the cognitive among core symptoms, but ATPDs, existing evidence brings mixed results. Our primary aim was to compare three domains (executive functioning/abstraction, speed processing working memory) patients diagnosed with ATPD SZ over 12-month period. Moreover, we explored how...
Background: The chronic course of schizophrenia typically results in severe social, vocational and functional impairment, interferes with patients’ autonomy, reduces quality life increases disability. Aims: aim our study was: (1) to assess social impairment outpatients from the Czech Republic Slovakia; (2) examine a relationship between functioning antipsychotic treatment demographic variables. Methods: Schizophrenia stable phase illness, treated current medication for minimum one month,...
Introduction Cognitive impairment is among the core features of schizophrenia. In a healthy population, cognitive deficit often linked with cannabis abuse, and although same would be expected in patients schizophrenia, research has presented contradictory results.Methods Participants were first-episode schizophrenia (FES) spectrum disorder who had been lifetime users (N = 30), FES non-users 53) as well controls (HC) also divided into 20) 49). All participants underwent an extensive...
There is a current debate about the ecological validity of executive function (EF) tests. Consistent with verisimilitude approach, this research proposes Ballet Executive Scale (BES), self-rating questionnaire that assimilates idiosyncratic behaviors classical dance community. The BES was administrated to 149 adolescents, students Cuban School. Results present Cronbach’s alpha coefficient .80 and split-half Spearman–Brown r SB = .81. An exploratory factor analysis describes bifactorial...
Background: Neuroactive steroids (NAS) affect neurotransmitter systems and cognition; thus, they play role in etiopathogenesis of psychiatric disorders. Aims: To examine cognition effects NAS on cognitive functioning first-episode psychosis patients their healthy siblings. Secondary aims were to verify whether deficit is an endophenotype higher levels represent a high-risk factor for psychosis. . Methods: Studied were: (1) with first episode psychosis; (2) siblings the patients; (3) matching...
Cognitive flexibility (CF) is the ability to adapt cognitive strategies according changing environment. The deficit in CF has often been linked various neurological and psychiatric disorders including schizophrenia. However, operationalization assessment of have not unified current research suggests that available instruments measure different aspects CF. main objective present study was compare three frequently used neuropsychological measures CF-Wisconsin Card Sorting Test (WCST), Trail...
Imposing and controlling strain in materials such as semiconductors or ferroelectrics is a promising way to obtain new enhance existing properties. Although the field of engineering has seen rapid expansion over last two decades, straining semiconductor membranes large areas remains challenge. A generic tuning hence band structure electric magnetic properties any crystalline material can be obtained by compression composite involving poorly compressible elastomers. Mechanically similar...
Individuals recovering from COVID-19 may experience persistent impairment in verbal memory performance, potentially due to illness-related hippocampal injury. Although dysfunction is central schizophrenia, the interactions between this vulnerability and remain unclear, with no imaging studies addressing issue to-date. To explore gap generate hypotheses for future research, we adopted a multiple case study approach. Two pairs of individuals an ICD-10 diagnosis schizophrenia were selected,...
Objective: This study evaluates the equivalence of alternate forms to three frequently used neuropsychological test methods in their Czech versions, i.e. Rey Auditory Verbal Learning Test (RAVLT), Complex Figure (CFT) and letter categorical verbal fluency (VF). Method: In a within-subject design, fifty-nine healthy volunteers were assessed using original proposed forms, first at baseline then after months. The performance tests subjected T-test U-test for paired samples based on normality...
Toxoplasma is considered as one of the most promising candidates infectious agent that might trigger psychotic disorder in predisposed subjects or modulate course disease. A clinical pattern has not been established yet infected schizophrenia patients. Psychopathological, cognitive and treatment response features seropositive seronegative individuals suffering from spectrum studied China, Czech Republic, Ethiopia, Germany, Turkey, United States other countries to determine whether infection...
Schizophrenia is manifested in positive, negative and cognitive symptoms. Especially, the symptoms offer useful methodological approach for comparative studies using spatial navigation tasks both, schizophrenia patients animal models of deficit schizophrenia. In order to demonstrate cognition test validity pharmacological model, we designed two virtual inspired by previous research: Morris water maze Carousel maze. The newly-designed require tested subject navigate toward several hidden goal...