Guangqian Lan

ORCID: 0000-0002-8154-6229
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About
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Research Areas
  • Wound Healing and Treatments
  • Silk-based biomaterials and applications
  • Electrospun Nanofibers in Biomedical Applications
  • Hemostasis and retained surgical items
  • Surgical Sutures and Adhesives
  • Antimicrobial agents and applications
  • Silkworms and Sericulture Research
  • Nanoparticles: synthesis and applications
  • Graphene and Nanomaterials Applications
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Advanced Cellulose Research Studies
  • Periodontal Regeneration and Treatments
  • Cerebral Venous Sinus Thrombosis
  • Advanced biosensing and bioanalysis techniques
  • Antimicrobial Peptides and Activities
  • Pickering emulsions and particle stabilization
  • Polymer composites and self-healing
  • Nanoplatforms for cancer theranostics
  • Extracellular vesicles in disease
  • Dyeing and Modifying Textile Fibers
  • Dermatologic Treatments and Research
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research
  • Enzyme-mediated dye degradation
  • Blood Coagulation and Thrombosis Mechanisms
  • Blood transfusion and management

Southwest University
2011-2024

State Key Laboratory of Silkworm Genomic Biology
2019-2023

Abstract Achieving rapid and safe control of perforating irregular hemorrhage, defined as bleeding wounds with external internal wound shape, located deep within complex covert hemorrhage sites, is vital to decrease the risk mortality during prehospital treatments surgical procedures. However, current hemostatic materials do not effectively their ability access source coagulate blood limited. Here, a biphasic Janus self‐propelled particle (MSS@CaCO 3 ) prepared via uniaxial growth...

10.1002/adfm.202004153 article EN Advanced Functional Materials 2020-08-19

Major challenges in traditional wound closure methods (e.g. using sutures and skin staplers) remain inadequately unaddressed; these invasive treatments induce extra puncture wounds, anesthetic side effects, severe scarring. Herein, an oxidized starch/gelatin-based shape memory hydrogel (OSG) was fabricated as a self-contracting dressing to facilitate noninvasive closure. The properties were attributed by introducing crosslink net-points the polymer structure through Schiff base reaction...

10.1016/j.matdes.2020.108916 article EN cc-by-nc-nd Materials & Design 2020-07-06

Preventing wound infection and retaining an appropriate level of moisture around wounds represent the most critical issues in treatment. Towards these ends, special focus has been placed on Bombyx mori cocoons because protective function silkworm cocoon resembles manner which skin protects human body. We have designed a facile technique to develop novel cocoon-based film (SCWF) dressing utilizing CaCl2-ethanol-H2O solution. To improve anti-bacterial performance SCWF, we incorporated ability...

10.1038/s41598-017-02270-6 article EN cc-by Scientific Reports 2017-05-12

Thrombosis can cause life-threatening disorders. Unfortunately, current therapeutic methods for thrombosis using injecting thrombolytic medicines systemically resulted in unexpected bleeding complications. Moreover, the absence of practical imaging tools thrombi raised dangers undertreatment and overtreatment. This study develops a theranostic drug carrier, Pkr(IR-Ca/Pda-uPA)-cRGD, that enables real-time monitoring targeted process deep vein (DVT). which is prepared from...

10.34133/research.0388 article EN cc-by Research 2024-01-01

Wound infection caused by multiantibiotic-resistant bacteria has become a serious problem, and more effective antibacterial agents are required. Herein, we report the preparation of wound dressings using biocompatible chitosan (CS) as reducing stabilizing agent in synthesis 2-mercapto-1-methylimidazole (MMT)-capped gold nanocomposites (CS-Au@MMT), with efficient effects. The synergistic effects AuNPs, MMT, CS led to disruption bacterial membranes. After blending gelatin, crosslinking tannin...

10.1088/1361-6528/aad7a7 article EN Nanotechnology 2018-08-02

Given that many people suffer from extensive skin damage, wound repair has drawn tremendous attention in research. Among the various assistant dressing materials promote healing, a porcine acellular dermal matrix (PADM), as substitute, can efficiently accelerate healing by promoting cell migration and proliferation. However, simple, low-cost preparation process remains challenge facing PADM development, particularly because of inferior elasticity. To overcome these drawbacks,...

10.1021/acsami.1c00420 article EN ACS Applied Materials & Interfaces 2021-04-05
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