A5039998258- Lung Cancer Diagnosis and Treatment
- Palliative Care and End-of-Life Issues
- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- Tracheal and airway disorders
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Metastasis and carcinoma case studies
- Pleural and Pulmonary Diseases
- Airway Management and Intubation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic Disease and Treatment Approaches
- Medical Imaging and Pathology Studies
- Bariatric Surgery and Outcomes
- Family and Patient Care in Intensive Care Units
- Patient-Provider Communication in Healthcare
- Childhood Cancer Survivors' Quality of Life
- Cancer survivorship and care
- Trauma Management and Diagnosis
- Esophageal and GI Pathology
- Head and Neck Cancer Studies
- Patient Dignity and Privacy
- Frailty in Older Adults
- Gastrointestinal Tumor Research and Treatment
- Cardiac and Coronary Surgery Techniques
University of Southern California
2023-2025
Keck Hospital of USC
2024
Yale University
2013-2024
New York Proton Center
2024
Massachusetts General Hospital
2016-2023
Harvard University
2018-2023
Yale New Haven Hospital
2022-2023
University of Virginia
2021
Presbyterian Hospital
2021
Cornell University
2021
Tissue engineered vascular grafts (TEVGs) have the potential to overcome issues faced by existing small diameter prosthetic providing a biodegradable scaffold where patient's own cells can engraft and form functional neotissue. However, applying classical approaches create arterial TEVGs using slow degrading materials with supraphysiological mechanical properties, typically results in limited host cell infiltration, poor remodeling, stenosis, calcification. The purpose of this study is...
Palliative surgical procedures are frequently performed to reduce symptoms in patients with advanced cancer, but quality is difficult measure.To determine whether natural language processing (NLP) of the electronic health record (EHR) can be used (1) identify a population cancer receiving palliative gastrostomy and (2) assess documentation end-of-life process measures EHR.Retrospective cohort study 302 adult who received tube at single tertiary medical center.Sensitivity specificity NLP...
Tissue-engineered blood vessels (TEVs) are typically produced using the pulsatile, uniaxial circumferential stretch to mechanically condition and strengthen arterial grafts. Despite improvements in mechanical integrity of TEVs after conditioning, these tissues fail achieve critical properties native arteries such as matrix content, collagen fiber orientation, strength. As a result, uniaxially loaded can result failure, thrombus, or stenosis on implantation. In planar tissue equivalents...
The surgical repair of heart and vascular disease often requires implanting synthetic grafts. While grafts have been successfully used for medium-to-large sized arteries, applications small diameter arteries (<6 mm) is limited due to high rates occlusion by thrombosis. Our objective was develop a tissue engineered graft (TEVG) arteries. TEVGs composed polylactic acid nanofibers with inner luminal between 0.5 0.6 mm were surgically implanted as infra-renal aortic interposition conduits in 25...
Background: Alone, administrative data poorly identifies patients with palliative care needs. Objective: To identify uncommon, yet devastating, illnesses using a combination of and natural language processing (NLP). Design/Setting: Retrospective cohort study the electronic medical records healthcare network totaling over 2500 hospital beds. We sought to patient populations two unique disease processes associated poor prognosis: pneumoperitoneum leptomeningeal metastases from breast cancer....
Background: Palliative care consultation during serious life-limiting illness can reduce symptom burden and improve quality of care. However, quantifying the impact palliative is hindered by limitations manual chart review administrative coding. Objectives: Using novel natural language process (NLP) techniques, we examined associations between consultations performance on nationally endorsed metrics for high-quality end-of-life (EOL) in patients with leptomeningeal disease (LMD) secondary to...
Our approach for fabricating tissue-engineered vascular grafts (TEVG), applied in the surgical management of congenital heart disease, is accomplished by seeding isolated bone marrow-derived mononuclear cells (BM-MNCs) onto biodegradable scaffolds. The current method used isolation BM-MNCs density centrifugation Ficoll. This a time-consuming, labor-intensive, and operator-dependent method. We previously demonstrated that simpler, faster, operator-independent isolating using filter elution...
Background: Non-intubated thoracoscopic surgery with spontaneous breathing is rarely utilized, but may have several advantages over standard intubation, especially in those significant cardiopulmonary comorbidities. In this study we evaluate the safety, feasibility, and 3-year survival of without endotracheal intubation for oncologic non-oncologic indications. Methods: All consecutive patients [2018–2022] selected lung resection or other pleural space intervention under local anesthesia...