- Inflammatory Biomarkers in Disease Prognosis
- Hip and Femur Fractures
- Nitric Oxide and Endothelin Effects
- Drug Transport and Resistance Mechanisms
- Cancer, Lipids, and Metabolism
- Mental Health via Writing
- Immune cells in cancer
- Schizophrenia research and treatment
- Pelvic and Acetabular Injuries
- COVID-19 Clinical Research Studies
- Pharmacogenetics and Drug Metabolism
- Inflammatory mediators and NSAID effects
- Venous Thromboembolism Diagnosis and Management
- Head and Neck Cancer Studies
- Cerebrovascular and Carotid Artery Diseases
- Platelet Disorders and Treatments
- Cardiovascular Health and Disease Prevention
- Cancer-related molecular mechanisms research
- Acute Myocardial Infarction Research
- Bone and Joint Diseases
- Ferroptosis and cancer prognosis
- Cardiovascular Function and Risk Factors
- Mental Health Research Topics
- Biomarkers in Disease Mechanisms
Sun Yat-sen University Cancer Center
2023-2024
State Key Laboratory of Oncology in South China
2024
Sun Yat-sen University
2023-2024
Nanjing Medical University
2022
Deyang Stomatological Hospital
2020
Chongqing Emergency Medical Center
2020
Chongqing University
2020
Peking Union Medical College Hospital
2019
GTx (United States)
2019
Fu Wai Hospital
2016-2019
Abstract Background The systemic immune-inflammation index (SII), based on peripheral platelet, neutrophil and lymphocyte counts, has been proven to be a promising prognostic indicator in various diseases. Hip fracture is common injury among the older adults, become global public health problem with high mortality disability rates. However, relationship between SII prognosis of hip not yet well-known. aim this study was explore predictive value adults undergoing surgery. Methods This...
The neutrophil–lymphocyte ratio (NLR) is an emerging cardiovascular risk factor. Patients with mixed plaques (MPs) or noncalcified (NCPs) have a higher of poor outcomes. However, there are few published data on the relationship between NLR and presence NCP MP (NCP/MP). We retrospectively collected clinical laboratory 598 patients chest pain. According to whether they had coronary atherosclerotic characteristics most stenotic plaque, we divided them into no calcified plaques, NCP, MP. Those...
Noncalcified plaques (NCPs) and mixed (MPs) are considered as the high-risk coronary plaques. Endothelin-1 (ET-1) is a vasoactive peptide shows high expression in vulnerable plaque. The aim of this study to investigate relationship between bigET-1, precursor ET-1, NCPs/MPs Chinese population.A total 513 patients with chest pain suspected artery disease were collected divided into three groups no plaques, calcified or according characteristics all It demonstrated that associated elevated...
Abstract Objectives This study aimed to investigate the incidence, consequences, and predictors of serious chemotherapy‐induced thrombocytopenia (CIT) in nasopharyngeal carcinoma (NPC). Materials Methods We retrospectively reviewed clinical records patients with NPC between 2013 2015. Multivariate Cox proportional hazards regression model propensity score matching were used estimate effect CIT on overall survival. Univariate multivariate logistic analyses applied identify CIT. Results...
Objective To explore the relationship between different serum albumin and lymphocyte levels in patients with 2019-novel coronavirus (2019-nCoV) pneumonia (COVID-19). Methods A retrospective study was performed to identify characteristics of clinical data 205 COVID-19 who were hospitalized Happy Street Hanchuan People's Hospital, Xiaogan, Hubei Province from January 24 February 12, 2020, including their general information, (ALB) levels, counts (LYM), percentage lymphocytes (LYM%)...
Objective:To explore the relationship between preoperative blood indexes, clinicopathological characteristics and prognosis of patients with laryngeal squamous cell carcinoma(LSCC), to establish a nomogram for predicting survival recurrence time LSCC patients. Methods:The clinical data 530 who received primary surgical treatment were analyzed retrospectively. The randomly divided into training group testing according ratio 7∶3. nomograms overall survival(OS) recurrence-free survival(RFS)...
目的 探讨结直肠癌患者血清可溶性细胞间黏附分子1(sICAM-1)、外周血中性粒细胞-淋巴细胞比值(NLR)变化及其临床意义。 方法 检测2017年7月至2018年9月简阳市人民医院确诊的结直肠癌患者90例(病例组)以及90名健康者(对照组)血清sICAM-1、外周血NLR水平,并分析不同临床病理特征的结直肠癌患者术前血清sICAM-1水平、外周血NLR差异。 结果 病例组的术前血清sICAM-1、外周血NLR水平显著高于对照组,差异有统计学意义(t=18.097、8.683,均P<0.01);发生淋巴结转移、临床分期Ⅲ~Ⅳ期或分化程度低的结直肠癌患者中sICAM-1的表达水平较高(P<0.05);发生淋巴结转移的患者外周血NLR值显著高于未发生转移的患者,差异有统计学意义(P=0.001)。 结论 结直肠癌患者血清sICAM-1水平、外周血NLR升高,并且与肿瘤的发生、发展具有一定的相关性。