Leen Van den Steen

ORCID: 0000-0002-8158-7629
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About
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Research Areas
  • Dysphagia Assessment and Management
  • Voice and Speech Disorders
  • Head and Neck Cancer Studies
  • Oral health in cancer treatment
  • Obstructive Sleep Apnea Research
  • Tracheal and airway disorders
  • Nutrition and Health in Aging
  • Phonetics and Phonology Research
  • Esophageal and GI Pathology
  • Speech Recognition and Synthesis
  • Child Nutrition and Feeding Issues
  • Hearing Loss and Rehabilitation
  • Stuttering Research and Treatment
  • Exercise and Physiological Responses
  • Interpreting and Communication in Healthcare
  • Salivary Gland Disorders and Functions

Antwerp University Hospital
2015-2025

University of Antwerp
2019-2025

Abstract Background Acute and late toxicity after intensity‐modulated radiotherapy (IMRT) for head neck cancer (HNC) impacts on patient quality of life; yet, very data remain scarce. This study assessed dysphagia, xerostomia, fibrosis 3‐8 years IMRT. Methods A retrospective analysis using generalized estimated equations was performed 60 patients with HNC treated fractionated IMRT between 2000 2015 who had a follow‐up ≥8 years. Toxicity scored LENT‐SOMA scales. Results trend towards nonlinear...

10.1002/hed.25880 article EN Head & Neck 2019-07-22

ABSTRACT Background Radiotherapy (RT) in head and neck cancer (HNC) can cause multiple side effects such as nausea, pain, taste loss, fatigue, oral mucositis, xerostomia, acute radiation‐associated dysphagia (RAD). These factors threaten patients' intake (OI) during this RT. Reduced OI weight dehydration, malnutrition, various comorbidities. On top, reduced significantly affects quality of life may contribute to RAD through the disuse swallowing muscles. With aim maximizing retention a...

10.1002/hed.28089 article EN cc-by-nc-nd Head & Neck 2025-01-24

<b><i>Objective:</i></b> The aim of this study was to define patient characteristics a dysphonic population in terms voice disorder, gender, age, and subjective objective vocal parameters explore the relevant most frequent groups disorders. <b><i>Patients Methods:</i></b> Patient records from 4,447 subjects referred for assessment and/or therapy were analyzed. <b><i>Results:</i></b> Significantly more cases dysphonia...

10.1159/000369339 article EN Folia Phoniatrica et Logopaedica 2015-01-01

Abstract Background Dysphagia is a common and serious complication after (chemo)radiotherapy (CRT) for head-and-neck cancer (HNC) patients. Prophylactic swallowing exercises (PSE) can have significantly positive effect on post-treatment function. However, low adherence rates are key issue in undermining this effect. This current randomized trial will investigate the of adherence-improving measures patients’ function, quality life (QOL). Methods ongoing explore difference swallowing-related...

10.1186/s13063-020-4171-0 article EN cc-by Trials 2020-03-02

Reduced tongue strength is an important factor contributing to early and late dysphagia in head neck cancer patients previously treated with chemoradiotherapy. The evidence growing that strengthening exercises can improve swallowing function both healthy dysphagic subjects. However, little known about the impact of specific features exercise protocol for on actual outcome (strength or function). Previous research originating fields sports medicine physical rehabilitation shows degree load...

10.1186/s13063-015-0889-5 article EN cc-by Trials 2015-09-04

Abstract Background Radiation‐associated dysphagia (RAD) is highly prevalent in head and neck cancer (HNC) patients, with insufficient tongue strength (TS) as a characteristic of this disabling complication. The effects tongue‐strengthening exercises (TSE) on TS, swallowing, quality life (QoL) have not been studied population. Methods A prospective phase 2 study using an 8 weeks during TSE protocol was carried out 15 patients chronic RAD. Outcome parameters were maximal isometric pressure...

10.1002/hed.26179 article EN Head & Neck 2020-04-30

Prophylactic swallowing exercises (PSE) during radiotherapy can significantly reduce dysphagia after in head and neck cancer (HNC). However, its positive effects are hampered by low adherence rates the burdensome therapy period. Hence, main goal of this multicenter randomized controlled trial (RCT) was to investigate effect 3 different service-delivery modes on actual patients' adherence.A total 148 oropharyngeal patients treated with primary (chemo)radiotherapy were randomly assigned a 4...

10.1007/s00455-022-10513-6 article EN cc-by Dysphagia 2022-09-19

Abstract Prophylactic swallowing exercises (PSE) during head-and-neck cancer (HNC) (chemo)radiotherapy (CRT) have a positive effect on function and muscle strength. Adherence rates to PSE are, however, moderate low, undermining these effects. PRESTO already showed that the service-delivery mode (SDM), way are offered, can influence adherence. The aim of this study was investigate SDM strength post-CRT. In addition, overall adherence (OA), independent SDM, also investigated. A total 148 HNC...

10.1007/s00455-023-10609-7 article EN cc-by Dysphagia 2023-08-08

Abstract Background Radiation‐associated‐dysphagia is a serious side effect of radiotherapy (RT) for head and neck cancer (HNC). Methods Seventy‐six patients had weekly prospective follow‐up from baseline until one week post‐RT. Combined mixed model analysis ( n = 43) determined the evolution self‐perceived swallowing function, isometric tongue strength (MIP), (TS) during (Pswal), quality life (QoL) in these RT. Results Swallowing deteriorated third on, resulting an increase tube dependency...

10.1002/hed.25684 article EN Head & Neck 2019-02-14

<b><i>Introduction:</i></b> Positive effects from tongue-strengthening exercises (TSE) are widely described, but dose-dependent studies concerning exercise frequency have not yet been reported. This study aimed to determine the training and detraining of TSE with frequencies respectively 3 5 times per week on maximum isometric anterior posterior tongue pressures (MIP<sub>A</sub> MIP<sub>P</sub>) strength during an effortful saliva swallow...

10.1159/000505153 article EN Folia Phoniatrica et Logopaedica 2020-02-05

Abstract Background The articulatory accuracy of patients with dysarthria is one the most affected speech dimensions a high impact on intelligibility. Behavioural treatments articulation can either involve direct or indirect approaches. latter have been thoroughly investigated and are generally appreciated for their almost immediate effects number studies (short‐term) therapy limited. Aims To investigate short‐term, boost (BArT) intelligibility in chronic progressive effect severity outcome....

10.1111/1460-6984.12595 article EN cc-by-nc-nd International Journal of Language & Communication Disorders 2021-01-23

Abstract Background Chronic radiation-associated dysphagia (C-RAD) is considered to be one of the most severe functional impairments in head and neck cancer survivors treated with radiation (RT) or chemoradiation (CRT). Given major impact these late toxicities on patients’ health quality life, there a strong need for evidence-based management. Although studies report benefit strengthening exercises, transference changes muscle strength swallowing function often remains limited. Therefore,...

10.1186/s13063-022-06832-6 article EN cc-by Trials 2022-10-22

Abstract Background Several conditions and diseases can result in speech problems that have a negative impact on everyday functioning, referred to as communicative participation. Subjective with acquired are often assessed the handicap index (SHI). To assess generic participation problems, Utrecht Scale for Evaluation of Rehabilitation–Participation (USER‐P) questionnaire is frequently used. The English Communicative Participation Item Bank—short form (CPIB short form) 10‐item valid,...

10.1111/1460-6984.12775 article EN cc-by-nc-nd International Journal of Language & Communication Disorders 2022-09-05

ABSTRACT Background Imprecise articulation has a negative impact on speech intelligibility. Therefore, treatment of is clinically relevant in patients with dysarthria. In order to be effective and according the principles motor learning, therapy needs intensive, well organized, adequate feedback requires frequent practice. Aims The aims this pilot study are (1) evaluate feasibility virtual (VAT) guide dysarthria through boost (BArT) program; (2) acoustic models’ performance used for...

10.1111/1460-6984.12647 article EN International Journal of Language & Communication Disorders 2021-07-06

Abstract Background Acute and late toxicities in patients treated with (chemo)radiotherapy for head neck cancer (HNC) is common can negatively impact quality of life performance. Performance status instruments measure the functional ability to perform daily activities are important tools oncologic population. Aims Since Dutch performance scales HNC population lacking, we conducted this study translate Status Scale Head Neck Cancer Patients (PSS‐HN) into (D‐PSS‐HN) validate version. Methods...

10.1111/1460-6984.12894 article EN cc-by-nc-nd International Journal of Language & Communication Disorders 2023-05-15

Dysprosody is a hallmark of dysarthria, which can affect the intelligibility and naturalness speech. This includes sentence accent, helps to draw listeners’ attention important information in message. Although some studies have investigated this feature, we currently lack properly validated automated procedures that distinguish between subtle performance differences observed across speakers with dysarthria. study aims for cross-population validation set acoustic features previously been...

10.3390/brainsci11101344 article EN cc-by Brain Sciences 2021-10-13
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