A5101991217- Heparin-Induced Thrombocytopenia and Thrombosis
- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Intramuscular injections and effects
- Venous Thromboembolism Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Platelet Disorders and Treatments
- Blood transfusion and management
- Congenital Heart Disease Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Acute Ischemic Stroke Management
- Cardiovascular Health and Disease Prevention
- Cardiac Arrest and Resuscitation
- Cardiac pacing and defibrillation studies
- Cardiac and Coronary Surgery Techniques
- Thermal Regulation in Medicine
- Cardiovascular Function and Risk Factors
- Aortic aneurysm repair treatments
- Case Reports on Hematomas
- Trauma and Emergency Care Studies
- Acute Myocardial Infarction Research
- Respiratory Support and Mechanisms
- Complement system in diseases
Saitama Medical University
2024
Kurosawa Hospital
2024
National Cerebral and Cardiovascular Center
2014-2023
Tokyo Medical and Dental University Hospital
2016-2021
Scripps Research Institute
2020-2021
Tokyo Medical and Dental University
2017
Nagoya University
2011
Recent studies suggest that a thromboembolic disorder resembling heparin-induced thrombocytopenia (HIT), so-called spontaneous HIT syndrome, can occur in patients without any history of heparin exposure. It is likely due to anti-platelet factor 4 (PF4)/polyanion antibodies induced by other polyanions, such as bacterial surfaces and nucleic acids. We describe an atypical case syndrome. A 70-year-old man suddenly presented with acute cerebral sinus thrombosis (CST). Soon after the initiation...
The present study aimed to examine the association between tranexamic acid use and adverse effects (seizures, thromboembolism, renal dysfunction) in a pediatric trauma population using national inpatient database Japan. We also assessed in-hospital mortality.A nationwide, retrospective cohort propensity score analyses.Japanese Diagnosis Procedure Combination database.Pediatric patients less than or equal 12 years old admitted hospital with diagnosis of July 2010 March 2014 (n =...
This paper describes improvement of torque control system permanent magnet synchronous motor (PMSM) based on model predictive (MPC). MPC controller selects directly one the voltage vector PWM inverter by estimating and evaluating future states (torque, current) PMSM instead generating reference as conventional one. The sequence selected vectors makes output appropriate transient state in addition toone steady state. As a result, this obtains fast current response. time resolution voltage,...
To diagnose heparin-induced thrombocytopenia (HIT), detection of platelet-activating antibodies (HIT antibodies) is crucial. However, serum platelet activation profiles vary across patients and depend on test conditions. We evaluated the association between clinical outcomes assessed by a microparticle assay (PMA), which detects washed platelets induced HIT antibodies, in 401 consecutive clinically suspected having HIT. made modifications to assay, such as donor selection for that increased...
Radiation therapy is performed as an adjuvant when indicated following surgical resection of malignant tumors. However, radiation exposure induces acute or chronic dermatitis, depending on the dose, interval, tissue volume, irradiated area body. Radiation-induced skin ulcers and osteomyelitis underlying bone are intractable late-stage complications therapy, often require reconstructive surgery to cover exposed tissue. Hyperbaric oxygen has been suggested a treatment for delayed injury with...
Abstract While plasma exchange (PE) can eliminate proteins, including all immunoglobulin (Ig) and coagulation factors, selective (SePE) retain fibrinogen (Fbg). Here, we investigated the removal dynamics of Ig Fbg in 53 patients with immunological disorders by PE, SePE, a combination two. When mean processed volume (PPV) was 0.9 (PV), percent reductions PE were both approximately 62%–65%. PPV 1.1 PV, SePE 53.1% for IgG, 30.1% IgA, 3.6% IgM, 19.0% Fbg, respectively. In three plasmapheresis...
Guideline 大量出血症例に対する血液製剤の適正な使用のガイドライン宮田 茂樹 1) 板倉 敦夫 2) 上田 裕一 3) 碓氷 章彦 4) 大北 裕 5) 大西 佳彦 6) 香取 信之 7) 久志本成樹 8) 佐々木啓明 9) 志水 秀行 10) 西村 邦宏 11) 西脇 公俊 12) 松下 正 13) 小川 覚 14) 紀野 修一 15) 久保 隆彦 16) 齋藤 伸行 17) 田中 裕史 18) 田村 高廣 19) 中井 陸運 藤井 聡 20)
Hyperbaric oxygen (HBO) exposure for 10-15 min has been shown to reduce peripheral blood flow due vasoconstriction. However, the relationship between decreased and therapeutic effects of HBO treatment on circulatory disorders remain unknown. Longer exposures have reported vasodilatory increase flow. This study investigated effect transcutaneous pressure (TcPO2).Twenty healthy volunteers aged 20-65 years (nine males) participated in this study. All participants breathed 60 at 253.3 kPa....
Epicardial pacemaker wire insertion is standard following cardiothoracic surgery. However, undersensing of pacing wires may cause the R-on-T phenomenon, which induces ventricular fibrillation. We report a case male patient with severe mitral regurgitation scheduled for valve replacement who experienced two fibrillation episodes related to phenomenon caused by epicardial wire. Both events happened despite an appropriately low sensing threshold. Notably, stimulated T wave followed QRS...
Abstract Pemphigus vulgaris is a serious autoimmune skin disorder associated with desmoglein 1 and 3. Selective plasma exchange (SePE) for pemphigus remains unknown. We investigated the removal characteristics of autoantibodies, immunoglobulins, fibrinogen in three cases. When mean processed volume SePE was 1.2 volumes, percent reduction 50.7% 1, 48.9% 3, 50.3% IgG, 29.8% IgA, 1.9% IgM, 17.6% fibrinogen. In one case, after four sessions within eight days 87.0% 85.1% 76.6% 53.5% 7.9% 41.6%...