Shintaro Makino

ORCID: 0000-0003-0258-361X
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About
Contact & Profiles
Research Areas
  • Maternal and fetal healthcare
  • Pregnancy and preeclampsia studies
  • Maternal and Perinatal Health Interventions
  • Uterine Myomas and Treatments
  • Ectopic Pregnancy Diagnosis and Management
  • Pregnancy-related medical research
  • Preterm Birth and Chorioamnionitis
  • Reproductive System and Pregnancy
  • Cardiovascular Issues in Pregnancy
  • Neonatal Respiratory Health Research
  • Congenital Diaphragmatic Hernia Studies
  • Birth, Development, and Health
  • Pregnancy and Medication Impact
  • Blood Coagulation and Thrombosis Mechanisms
  • Systemic Lupus Erythematosus Research
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Pelvic floor disorders treatments
  • Gestational Diabetes Research and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • RNA modifications and cancer
  • Gestational Trophoblastic Disease Studies
  • Endometriosis Research and Treatment
  • Hernia repair and management
  • Cancer-related gene regulation
  • Minimally Invasive Surgical Techniques

Juntendo University Urayasu Hospital
2020-2025

Juntendo University
2015-2024

Kobe University Hospital
2023

Health Affairs
2022

Niigata University
2020

Juntendo University Hospital
2017-2019

Arrowhead Regional Medical Center
2019

University of Alberta
2006-2019

Makerere University
2019

Royal Alexandra Hospital
2019

The 2017 clinical guidelines for obstetrical practice by the Japan Society of Obstetrics and Gynecology Association Obstetricians Gynecologists were revised published as 2020 edition (in Japanese). aim these is to present appropriate standard obstetric diagnosis management procedures that have reached consensus among Japanese obstetricians. include 113 questions an appendix, followed answers (CQ&A; originally 112 in edition), a discussion, list references, some tables figures presenting...

10.1111/jog.15438 article EN Journal of Obstetrics and Gynaecology Research 2022-10-17

Group B streptococcus (GBS) is a major global cause of neonatal, infant, and maternal infections. In Japan, national guidelines based on Centers for Disease Control Prevention recommendations mandate culture-based screening intrapartum antibiotic prophylaxis (IAP) GBS-positive pregnant women. Despite initial reductions in GBS infections, the incidence has plateaued, there are notable limitations current prevention methods. Approximately 15% women not screened GBS, intermittent colonization...

10.1017/s0950268824001560 article EN cc-by-nc-nd Epidemiology and Infection 2025-01-01

Perinatal care in Japan has progressed rapidly recent decades, remarkably reducing maternal, perinatal and neonatal mortality rates. This is attributable not only to the sustained efforts dedication of past obstetricians midwives, but also collective results achieved by Society Obstetrics Gynecology healthcare administration, including research on advanced medical care, education, improvements establishing centers. Although maternal rate was steady decline until 2007 (3.1/100 000 births), it...

10.1111/jog.13184 article EN Journal of Obstetrics and Gynaecology Research 2017-01-01

Preeclampsia (PE) is a hypertensive disorder specific to pregnancy that can cause severe maternal-neonatal complications. The International Society for the Study of Hypertension in Pregnancy revised PE criteria 2018; diagnosis be established absence proteinuria when organ or uteroplacental dysfunction occurs. initial findings (IFsPE) at first vary considerably across patients. However, impacts different IFsPE on patient prognoses have not been reported. Thus, we investigate predictors...

10.1186/s12884-021-04152-2 article EN cc-by BMC Pregnancy and Childbirth 2021-10-06

Our study aimed to evaluate the effectiveness of ultrasound-indicated cerclage in singleton pregnancies with cervical shortening (<25 mm), excluding those a history preterm birth (PTB) and infection/inflammation.

10.1111/jog.16173 article EN Journal of Obstetrics and Gynaecology Research 2025-01-01

Abstract Aim The purpose of this study is to clarify the frequencies fresh frozen plasma (FFP) ± fibrinogen concentrate administration (fibrinogen [FC] therapy) and antithrombin (AT) (AT for women with obstetrical disseminated intravascular coagulation (DIC). Methods Two retrospective multicenter case–control studies as Study‐1 (January–December 2018) Study‐2 (July 2022–June 2023) were conducted. was historical control Study‐2. All participants experienced a blood loss ≥1000 mL during...

10.1111/jog.16220 article EN Journal of Obstetrics and Gynaecology Research 2025-01-29

The aim of this study was to provide basic documents applicable studying the usefulness administering fibrinogen concentrate patients with massive post-partum hemorrhage. We investigated usage at training institutions for specialist physicians Japan Society Obstetrics and Gynecology.The subjects were women who required hemostasis hemorrhage during period between April 2008 March 2013. underlying diseases, obstetric disseminated intravascular coagulation scores, blood loss, amount...

10.1111/jog.12708 article EN Journal of Obstetrics and Gynaecology Research 2015-05-27

The aim of the study was to explore sonographic findings fetuses with craniosynostosis and investigate their prognosis. We conducted a 5-year, multicenter retrospective collected data on patients diagnosed in perinatal period. Of 41 cases, 30 cases (73%) were syndromic craniosynostosis, eight (20%) non-syndromic other three (7%) secondary chromosomal deletion syndromes. prenatal ultrasound detection rate 61%. Half detected during period Pfeiffer syndrome; there also six Apert syndrome,...

10.1111/cga.12308 article EN Congenital Anomalies 2018-08-22

Objective: To describe the pre-conception status, pregnancy outcomes, and medication prevalence in systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Crohn's disease (CD), ulcerative colitis (UC).Methods: E-mail-based questionnaire survey for Japan Maternal Fetal Intensive Care Unit Network hospitals inquiring clinical features of SLE, RA, CD UC complicated pregnancies 2 years.Results: The number among 69,810 deliveries was 184, 139, 27 178, respectively. Less than half were...

10.1080/14397595.2019.1661592 article EN Modern Rheumatology 2019-09-04

Since July 2022, obstetrical disseminated intravascular coagulation (DIC) in Japan has been diagnosed based on the new criteria (tentative version), which assesses main underlying disease, fibrinogen level, and fibrin/fibrinogen degradation products or D-dimer level. In June 2024, tentative version underwent minor revision final was released. The previous Japanese assessed clinical symptoms, various laboratory findings. This study aimed to prove effectiveness, reliability, validity of (final...

10.1038/s41598-024-68298-7 article EN cc-by-nc-nd Scientific Reports 2024-07-30

Compression has been regarded as the main haemostatic mechanism of compression sutures; however, we suggest that reduced uterine blood flow may be another important action. We our ‘double vertical sutures’ have dual actions: bleeding surface and flow.

10.1111/j.1479-828x.2012.01422.x article EN Australian and New Zealand Journal of Obstetrics and Gynaecology 2012-03-13

Abstract Uterine artery embolization ( UAE ) is a common treatment for post‐partum hemorrhage and uterine fibroids. However, the effects of on subsequent pregnancies have not been established. Here, we present case spontaneous rupture after previous . A 31‐year‐old woman underwent cervical ectopic pregnancy. Contrast‐enhanced magnetic resonance imaging MRI at days 5 25 post‐ suggested regionally decreased blood supply in mid‐posterior wall fundus. During pregnancy age 35 years, she an...

10.1111/jog.12122 article EN Journal of Obstetrics and Gynaecology Research 2013-08-15

Ether and restraint stress-induced peripheral plasma corticotropin releasing hormone (CRH), arginine vasopressin (AVP), oxytocin (OXY) adrenocorticotropin (ACTH) levels were measured by radioimmunoassays. Plasma CRH, AVP, OXY ACTH rose to approximately twice the level of control rats 2 min after onset a 1-min exposure ether. CRH further 5 ether stress, while AVP returned baseline at min. showed significant elevation did not show change. whereas levels. concentrations in hypothalamic median...

10.18926/amo/30888 article EN PubMed 1989-06-01

Congenital heart block (CHB) is the most serious manifestation of neonatal lupus syndrome (NLS), and maternal antibodies directed against 52-kd SSA/Ro 48-kd SSB/La antigens have been reported to be more strongly associated with CHB than those 60-kd antigen alone (1). The important treatment strategy for preventive, based on therapy a fluorinated steroid plasmapheresis during pregnancy (2). We treated both patients who were seropositive anti-52-kd anti-48-kd or had high titers only...

10.1080/00016340701343024 article EN Acta Obstetricia Et Gynecologica Scandinavica 2007-08-22

Time spatial labeling inversion pulse (Time-SLIP) is a non-contrast magnetic resonance angiography (MRA) technique. No cases in which this technique was used during pregnancy have been reported. We report herein two with adenomyosis of the same size and location that underwent Time-SLIP MRA pregnancy. In case 1, blood flow within poor, uterine toward placenta normal, resulting no fetal growth restriction (FGR). 2, quite rich, placental seemed decreased, severe FGR. As well as Doppler...

10.1111/jog.12088 article EN Journal of Obstetrics and Gynaecology Research 2013-07-15
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