- MicroRNA in disease regulation
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Autoimmune Bullous Skin Diseases
- Online Learning and Analytics
- Public Health and Nutrition
- Genomics, phytochemicals, and oxidative stress
- Diet and metabolism studies
- Bone Tissue Engineering Materials
- Natural Products and Applications
- Colorectal Cancer Screening and Detection
- Biomarkers in Disease Mechanisms
- Protease and Inhibitor Mechanisms
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Dietary Effects on Health
- Competitive and Knowledge Intelligence
- Mechanical Circulatory Support Devices
- Technology Adoption and User Behaviour
- Dermatological and Skeletal Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Mesenchymal stem cell research
- ICT in Developing Communities
- Genetics, Aging, and Longevity in Model Organisms
- Management and Optimization Techniques
- Animal Diversity and Health Studies
University Hospital Heidelberg
2020-2024
University Medical Centre Mannheim
2020-2024
Heidelberg University
2020-2024
University of North Carolina at Chapel Hill
2023
University of Dhaka
2023
Goryeb Children's Hospital
2022
University of Belgrade
2017
MicroRNAs (miRNAs) are involved in the regulation of various cellular processes including pathological conditions. MiRNA networks have been extensively researched age-related degenerative diseases, such as cancer, Alzheimer's disease (AD), and heart failure. Thus, miRNA has studied from different approaches, vivo, vitro, silico networks. Networks linking diverse biomedical entities unveil information not readily observable by other means. This work focuses on biological related to Breast...
Micro RNAs (miRNAs) have a key role in gene expression regulation cancer. The aim of the current study is to evaluate prognostic value miR-34b/c promoter hypermethylation, expression, and polymorphism HPV-negative oral squamous cell carcinomas (OSCC). MiR-34b/c hypermethylation pre-miR-34b/c rs4938723 were evaluated tumor tissues 148 patients, miR-34b 123 OSCC. For risk assessment, control group was comprised 175 healthy individuals. determined by methylation-specific PCR. Gene genotyping...
Acute myeloid leukemia (LAML) is one of the most prevalent hematological malignancies. In recent years, while targeted approaches have shown promise in fight against cancer, treatability and prognosis patients remain inadequate due to shortage drugs. Noncoding RNAs, especially circular RNA (circRNA) microRNA (miRNA), been play a unique role tumor development. This study aims identify disease-associated circRNA-miRNA-mRNA network by bioinformatic analysis investigate mechanisms development...
Fibroblasts are considered to play a major role in the development of fibrotic reaction after radiotherapy and premature radiation-induced differentiation has been proposed as cellular basis. The purpose was relate gene expression profiles phenotypic changes human skin fibroblasts relevant for radiogenic fibrosis. Exponentially growing or confluent fibroblast strains were irradiated vitro with 1-3 fractions 4 Gy X-rays. differentiated phenotype detected by cytomorphological scoring...
Previous studies have demonstrated that DNAJA1 could be a good indicator of beef toughness in Longissimus thoracis muscle from Charolais young bulls.This study aimed to check if relationship between expression and tenderness is valid two muscles, which differ Angus steers with or without electric stimulation at different times post-mortem ageing.Electric did not significantly affect the time slaughter.But, RNA degradation soon after slaughter was major factor, affected assessment expression,...
Sami, Ahmad Salah MD; Sylvester, Francisco A. Attard, Thomas Mir, Sabina MD Author Information
Camurati-Engelmann disease (CED) is a rare disorder caused by activating mutations in the TGF-β1 gene and characterized hyperostosis of long bones bone dysplasia. We describe case an adolescent with CED moderate-severe Crohn Disease (CD). Infliximab improved gastrointestinal symptoms but was associated worsening CED-associated pain. Clinical remission successfully achieved dual biologic therapy that included vedolizumab ustekinumab. Possible reasons for this patient's clinical response are...
With the introduction of new and improved technologies, conception rapid growth educational technology or Edtech has quickly gained success all over world. Bangladesh is no different to this trend, as a very lucrative sector emerged within last few years. This recent influx in platform expansion usage raises need for further investigation what factors influence platforms Bangladesh. To address research gap, study was conducted among 222 people who were aware their functionality The...