- Lymphoma Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- Chronic Lymphocytic Leukemia Research
- Advanced Breast Cancer Therapies
- Acute Lymphoblastic Leukemia research
- Breast Cancer Treatment Studies
- Chronic Myeloid Leukemia Treatments
- Nausea and vomiting management
- CNS Lymphoma Diagnosis and Treatment
- Neutropenia and Cancer Infections
- Viral-associated cancers and disorders
- Lung Cancer Treatments and Mutations
- Acute Myeloid Leukemia Research
- COVID-19 Clinical Research Studies
- Anesthesia and Pain Management
- Peptidase Inhibition and Analysis
- Head and Neck Cancer Studies
- Neuroblastoma Research and Treatments
- Cancer Treatment and Pharmacology
- Monoclonal and Polyclonal Antibodies Research
- Testicular diseases and treatments
- Cancer Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Childhood Cancer Survivors' Quality of Life
- Head and Neck Surgical Oncology
Cancer Institute (WIA)
2015-2024
National and Kapodistrian University of Athens
2017
Universitätsklinikum Tübingen
2017
University of Calgary
2017
National Institute of Immunohaematology
2017
Rajiv Gandhi Cancer Institute and Research Centre
2017
PURPOSE There are sparse data on the outcome of patients with locally advanced breast cancer (LABC). This report is prognostic factors and long-term from Cancer Institute, Chennai. METHODS an analysis untreated LABC (stages IIIA-C) who were treated January 2006 to December 2013. RESULTS Of 4,577 treated, 2,137 (47%) included for analysis. The median follow-up was 75 months (range, 1-170 months), 2.3% (n = 49) lost at 5 years. initial treatment neoadjuvant concurrent chemoradiation (NACR)...
Abstract Background Fosaprepitant is a neurokinin‐1 receptor antagonist, approved for the prevention of chemotherapy‐induced nausea and vomiting. The data on use fosaprepitant in children are limited therefore we conducted phase III randomized controlled trial. Procedure Children aged 1‐12 years scheduled to receive moderately or highly emetogenic chemotherapy were randomly assigned arm‐A (fosaprepitant) arm‐B (placebo). recruited received intravenous ondansetron plus dexamethasone followed...
Abstract Background Breakthrough chemotherapy–induced vomiting (CIV) is defined as CIV occurring after adequate antiemetic prophylaxis. Olanzapine and metoclopramide are two drugs recommended for the treatment of breakthrough in children, without evidence. We conducted an open‐label, single‐center, phase 3 randomized controlled trial comparing safety efficacy olanzapine treating CIV. Procedure Children aged 5‐18 years who developed receiving highly emetogenic chemotherapy or moderately were...
Pediatric Hodgkin lymphoma (HL) is a highly curable malignancy. Outcomes for pediatric HL may vary between developed and developing countries multiple reasons. This study was conducted to ascertain the outcomes of children with at our center identify risk factors recurrent disease.We analyzed 172 consecutive, previously untreated patients presenting from 2001 2010. Patients were treated either adriamycin, bleomycin, vinblastine, dacarbazine or cyclophosphamide, vincristine, prednisone,...
Crowded outpatient clinics and common wards in many hospitals low middle-income countries predispose children, caregivers, health care workers to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We report on the clinical features outcomes of 15 children cancer at our center who tested positive for SARS-CoV-2. Five out patients were symptomatic, one patient required intensive support. All study have recovered from SARS-CoV-2 without any sequelae resumed their treatment.
Multi-drug resistant (MDR) bacteria are associated with increased morbidity and mortality in children acute leukaemia. The present study was conducted to assess the prevalence of MDR stool cultures patients leukaemia at presentation hospital. results were then correlated blood when developed septicaemia.The involved analysis case records newly diagnosed less than 18 years age treated our centre from January 2015 December 2015. Stool sent within 72 hr hospital admission clinically indicated....
Introduction: Oral metronomic chemotherapy (OMC) is a less intensive and cost-effective palliative treatment modality in children with relapsed/refractory cancers low-middle income countries. We aimed to study the safety efficacy of OMC oral etoposide cyclophosphamide pediatric malignancies treated at our center.Patients Methods: This was retrospective from case records patients center 2011 2018. Patients <18 years old who received least one cycle were included study. Cyclophosphamide given...
There are no reported cases in the literature of primary renal synovial sarcoma pediatric patients. The management has been extrapolated from soft tissue sarcomas at other sites. We present a 4-year-old female who was suspected to have Wilms' tumor. patient underwent guided biopsy as she did not respond neoadjuvant chemotherapy for consistent with sarcoma. child treated change her regimen and surgery. diagnosis confirmed by demonstrating <i>t</i> (X, 18) translocation using polymerase chain reaction.
Cervical cancer is the third most common in India. There limited data on treatment of relapsed cervical from India; therefore, we report outcomes patients with recurrent who were treated palliative chemotherapy (CT).This was a retrospective study received CT January 2012 to December 2016. The demographic details, clinical profile and survival collected. Patients carboplatin or paclitaxel carboplatin. Local radiation given for symptomatic patients. assessed responses clinically and/or...
Neoadjuvant concurrent chemoradiation (CTRT) is not widely practiced in breast cancers. The current study presents our experience with the use of neoadjuvant CTRT patients locally advanced cancers (LABC) treated at center.The included all consecutive female inoperable stage III LABC Cancer Institute (W.I.A), Chennai, India, from December 2015 to September 2016. Data were collected retrospectively patients' case records. impact on pathological complete response (pCR) and survival was...
Pediatric nasopharyngeal carcinomas (NPCs) are rare tumors. There is paucity of data on outcomes in pediatric NPC from developing countries.The present study was conducted to ascertain the children with at our center.A retrospective analysis case records patients treated hospital performed.We analyzed 37 consecutive <18 years age between 2000 and 2015. Patients were concurrent chemoradiotherapy (CTRT) cisplatin 5-fluorouracil (5-FU) or CTRT cisplatin, followed by adjuvant chemotherapy...
Hepatoblastoma is a rare pediatric tumor arising from the liver. The present study was conducted to ascertain clinical profile and survival outcomes of patients with hepatoblastoma treated at our centre. We collected case records between January 2000 December 2016 analysed baseline characteristics, treatment details outcomes. Survival using Kaplan Meier method. Twenty-seven received centre during period. Median age 12 months 76% were males. commonest presenting symptom abdominal mass median...