A5013961837- Genomic variations and chromosomal abnormalities
- Acute Lymphoblastic Leukemia research
- Congenital heart defects research
- Ovarian function and disorders
- Prenatal Screening and Diagnostics
- Acute Myeloid Leukemia Research
- Genetics and Neurodevelopmental Disorders
- Reproductive Biology and Fertility
- Chromosomal and Genetic Variations
- Congenital Anomalies and Fetal Surgery
- Chronic Myeloid Leukemia Treatments
- Garlic and Onion Studies
- COVID-19 Clinical Research Studies
- Congenital Heart Disease Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Endometriosis Research and Treatment
- Ovarian cancer diagnosis and treatment
- Blood disorders and treatments
- Cardiovascular Health and Risk Factors
- Glutathione Transferases and Polymorphisms
- Genomics and Rare Diseases
- Cancer-related molecular mechanisms research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Hormonal and reproductive studies
- Sexual Differentiation and Disorders
Sri Ramachandra Institute of Higher Education and Research
2016-2025
Cancer Institute (WIA)
2020-2023
Central Council for Research in Yoga & Naturopathy
2022
McGill University
1969
King's College London
1933
Periodontitis is a chronic inflammatory disease which caused by destruction of the tissues that surrounds and supports tooth. Deregulation microRNAs has been reported to cause several diseases such as autoimmune disease, periodontitis, cancer. In present study, we have investigated expression pattern let-7a, miR-125b, miR-100, miR-21, RNA-binding protein LIN-28A among healthy individuals periodontitis patients. Total RNA was isolated from gingival tissue samples collected 100 The LIN-28...
Introduction: Diabetic Retinopathy (DR) is a microvascular complication of diabetes that damages the retina and primary cause irreversible vision loss among young adults working age worldwide. It important to understand risk factors, such as dyslipidemia, they have been linked pathogenesis progression this disease. Aim: To assess association lipid profiles with severity DR. Materials Methods: This cross-sectional study included 150 participants both genders type 2 diabetes, aged 35-80 years,...
Type 2 diabetes (T2D) etiology is highly complex due to its multiple roots of origin. Polygenic risk scores (PRS) based on genome-wide association studies (GWAS) can partially explain T2D risk. Asian Indian people have up six times higher developing than European people, and underlying causes this disparity are unknown. We performed targeted sequencing ten GWAS/candidate regions using endogamous Punjabi Sikh families replication unrelated from three other ethnic groups (EEGs). detect rare...
The <em>Journal of the Royal Microscopical Society</em> is oldest journal dedicated to science microscopy, publishing latest advances in microscopy techniques and novel areas application.
BackgroundPolycystic ovarian syndrome (PCOS) is a common hormonal disorder that women belonging to premenopausal age group encounter. Due its increasing incidence and burden of disease, re-searching the etiopathogenesis this essential need hour. Recently, role stress in pathogenesis has come into picture. Hence study was done find any significant difference hormone levels between PCOS healthy controls.MethodsA case-control conducted SRIHER from 2019 2021 which 250 participants were enrolled....
Amenorrhea is a normal clinical feature in prepubertal, pregnant, and postmenopausal females. It also accounts for 20% of patients with infertility. The physiology menstruation reproduction has strong correlation the expression X chromosome. Thus, role genetics terms diagnosis, risk assessment, genetic counseling significant. contribution to amenorrhea studied both at cellular molecular level aiming abnormalities chromosomes mutations genes. present study aimed performing chromosomal...
From a karyotype analysis of Poa annua (2n = 28) two large chromosomes, I and II, one small chromosome, XIV, as well three chromosome groups containing two, four five chromosomes have been identified. comparison the with that published exilis 14) supina 14), doubt is cast on theory an allotetraploid latter diploid species. The could be identified certainty existed in homologous pairs, indicating species originated from or other hitherto unidentified It suggested further work might reveal...
Journal Article Number and Behaviour of Chromosomes in Aloe litoralis Get access T. K. KOSHY, M.A., PH.D.(LOND.) Professor BotanyTrivandrum, Travancore Search for other works by this author on: Oxford Academic PubMed Google Scholar Annals Botany, Volume 1, Issue January 1937, Pages 43–58, https://doi.org/10.1093/oxfordjournals.aob.a083459 Published: 01 1937
Despite the advances in vitro fertilization (IVF), implantation success rate for infertile women remains approximately only 15%. In this study, we sought to determine whether failure after repeated IVF treatments is influenced by presence of common variants estrogen α, progesterone and follicle stimulating hormone receptor genes. The study population included three groups women: group 1 were 50 who had transfer ≥3 high-quality embryos during procedure without ever having a clinical...
Abstract Transient myeloproliferative disorder (TMD) is a self-limiting characteristically seen in neonates with Down syndrome or without somatic mosaicism. Trisomy-21 limited to the hematopoietic lineage alone has been described; awareness of which very important for appropriate evaluation and counseling phenotypically normal children. We report newborn TMD who presented at birth intracranial bleed secondary thrombocytopenia. Peripheral smear showed 10% blasts flow cytometry further...
Indians are known to have the highest rates of coronary artery disease (CAD), with conventional risk factors failing explain increased risk. Possible candidate genes study both environmental and genetic associated CAD is glutathione S-transferase (GST) family, as it involved in detoxification. This case–control assessed association between GSTM1 GSTT1 polymorphisms Indian patients CAD. Fifty 50 healthy volunteers were genotyped for two by polymerase chain reaction. The genotype frequencies...
MicroRNAs (miR) have been reported to be involved in hematopoiesis and the pathogenesis of several hematological malignant neoplasms. Single-nucleotide polymorphisms (SNPs) human miR genes may alter expression those influence predisposition childhood leukemia.To evaluate association rs2910164 G>C, rs57095329 A>G miRNA-146a ethnic South Asian children with acute lymphoblastic leukemia (ALL).Genotyping analysis using TaqMan Small RNA Assay was performed on 71 patients pathologically confirmed...
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) caused Coronavirus disease 2019 (COVID‑19) in early December, 2019. The begins as a with varied outcomes, from complete recovery to long‑standing complications, such distress, heart ailments and stroke. present study was undertaken identify the derangements liver function inflammatory status which may be used diagnose severity thus assess prognosis of patients COVID‑19 infection. conducted at tertiary care teaching hospital....
To assess the burden of type 2 diabetes (T2D) and its genetic profile in endogamous populations India given paucity data, we aimed to determine prevalence T2D estimate heritability using family-based cohorts from three distinct Endogamous Ethnic Groups (EEGs) representing Northern (Rajasthan [Agarwals: AG]) Southern (Tamil Nadu [Chettiars: CH] Andhra Pradesh [Reddys: RE]) states India. For comparison, data collected previously another North Indian Punjabi Sikh (SI) EEG was used. In addition,...