Mahaboob Shaik

ORCID: 0000-0003-4059-1709
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Mesenchymal stem cell research
  • Biomarkers in Disease Mechanisms
  • Facial Trauma and Fracture Management
  • Angiogenesis and VEGF in Cancer
  • Liver physiology and pathology
  • Organ Transplantation Techniques and Outcomes
  • Retinal Diseases and Treatments
  • Retinal Imaging and Analysis
  • Liver Disease Diagnosis and Treatment
  • Periodontal Regeneration and Treatments
  • Uterine Myomas and Treatments
  • Spinal Fractures and Fixation Techniques
  • Pelvic and Acetabular Injuries
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cardiovascular Health and Risk Factors
  • Telomeres, Telomerase, and Senescence
  • Dental Implant Techniques and Outcomes
  • Oral and Maxillofacial Pathology
  • Retinal and Optic Conditions
  • Genetic Associations and Epidemiology
  • Laser Applications in Dentistry and Medicine
  • Spinal Cord Injury Research
  • Psoriasis: Treatment and Pathogenesis
  • Diabetes Management and Education
  • Cardiovascular and Diving-Related Complications

Narayana Dental College and Hospital
2015-2025

Vijayanagara Institute of Medical Sciences
2022-2023

Jawaharlal Nehru Technological University, Hyderabad
2020

St. Joseph Dental College
2011-2017

Narayan Medical College and Hospital
2013-2015

Deccan College of Medical Sciences
2008-2010

Andhra Pradesh Forest Department
2010

Liver transplantation is the only existing modality for treating decompensated liver cirrhosis. Several factors, such as nonavailability of donors, combined with operative risks, complications associated rejection, usage immunosuppressive agents, and cost intensiveness, make this strategy available to a few people. With tremendous upsurge in mortality rate patients disorders worldwide, there need search an alternative therapeutic tool that can combat above limitations serve supportive...

10.3727/096368910x498241 article EN Cell Transplantation 2010-01-01

Liver transplantation is the only existing modality for treating decompensated liver cirrhosis. Several factors, such as nonavailability of donors, combined with operative risks, complications associated rejection, usage immunosuppressive agents, and cost intensiveness, make this strategy available to a few people. With tremendous upsurge in mortality rate patients disorders worldwide, there need search an alternative therapeutic tool that can combat above limitations serve supportive...

10.3727/096368909x484707a article EN Cell Transplantation 2010-04-01

Type 2 diabetes (T2D) etiology is highly complex due to its multiple roots of origin. Polygenic risk scores (PRS) based on genome-wide association studies (GWAS) can partially explain T2D risk. Asian Indian people have up six times higher developing than European people, and underlying causes this disparity are unknown. We performed targeted sequencing ten GWAS/candidate regions using endogamous Punjabi Sikh families replication unrelated from three other ethnic groups (EEGs). detect rare...

10.1038/s43856-025-00750-9 article EN cc-by-nc-nd Communications Medicine 2025-02-22

Background: AUB is a common but complicated clinical presentation and occurs in 15-20% of women between menarche to menopause significantly affects the women's health. Women with thyroid dysfunction often have menstrual irregularities, infertility increased morbidity during pregnancy. The objective present study find correlation disorders perimenopausal attending gynecology OPD. Methods: In study, fifty five patients were included evaluated for cause including abnormality. Thyroid function...

10.18203/2320-6012.ijrms20151171 article EN International Journal of Research in Medical Sciences 2015-01-01

Medical image analysis is recognised to be the most important research area for diagnosis and screening of a wide range medical problems. The commonly discussed diabetic retinopathy has become vital factor serious eye diseases leading blindness. Diabetes mellitus, remarkable metabolic disorder, rapidly increasing health threats worldwide. major cause Diabetic Retinopathy (DR) increase in blood insulin levels. DR lesion thresholds inferred have protective effects no benefits patients. From...

10.1504/ijcat.2020.112684 article EN International Journal of Computer Applications in Technology 2020-01-01

Previous studies showed associated periodontal disease with various systemic ailments. This research work was aimed at studying the presence and role of microflora on preeclampsia during pregnancy.A cross-sectional study designed pregnant women without chronic periodontitis, attending Narayana Medical College Hospital, Nellore, Andhra Pradesh, India, for prenatal checkups. After obtaining consents, 445 were recruited in study. On basis health, subjects grouped into Group 1 (women...

10.4103/jispcd.jispcd_341_19 article EN Journal of International Society of Preventive and Community Dentistry 2020-01-01

To assess the burden of type 2 diabetes (T2D) and its genetic profile in endogamous populations India given paucity data, we aimed to determine prevalence T2D estimate heritability using family-based cohorts from three distinct Endogamous Ethnic Groups (EEGs) representing Northern (Rajasthan [Agarwals: AG]) Southern (Tamil Nadu [Chettiars: CH] Andhra Pradesh [Reddys: RE]) states India. For comparison, data collected previously another North Indian Punjabi Sikh (SI) EEG was used. In addition,...

10.3389/fendo.2022.847692 article EN cc-by Frontiers in Endocrinology 2022-04-14

Background: The present study is undertaken to know the risk factors and consequences of asymptomatic bacteriuria in pregnant women attending Narayana Medical College Hospital, Nellore.Methods: 500 were recruited for after their consent participation. 85 with culture positive ASB paired healthy without compare feto maternal outcome. Results: Antenatal complications like anemia (35%), PROM (14%), preterm labour (18%), IUGR preeclampsia (5%) pyelonephritis (3.5%) higher group when compared...

10.18203/2320-1770.ijrcog20150700 article EN other-oa International Journal of Reproduction Contraception Obstetrics and Gynecology 2015-01-01

beta-Cell destruction and/or insufficient insulin production are the hallmarks of diabetes mellitus (type 1 diabetes). A hepatic progenitor from developing liver is sought to be one surrogate sources as pancreas and share a common precursor signals cardiac mesoderm. Production possible by transfecting pancreatic transcription factors that play important roles in development beta-cell. But, there always fear using genetically manipulated cells for therapeutics. Hence, present study was...

10.1089/dia.2009.0083 article EN Diabetes Technology & Therapeutics 2010-04-14

Chronic kidney disease (CKD) is a growing problem worldwide. Clinical and epidemiologic studies have shown that structural functional changes occur in major arteries are contributing factor to the high mortality uremic patients. Recent stepwise increase of carotid-femoral pulse wave velocity (cfPWV) from CKD Stage 1 5. We evaluated cfPWV augmentation index (AIx), as indirect markers arterial stiffness patients with nondiabetic compared values normal population; we also relationship between...

10.4103/1319-2442.198136 article EN cc-by-nc-sa Saudi Journal of Kidney Diseases and Transplantation 2017-01-01

Background. Conventional mechanical debridement alone cannot eliminate bacteria and their products from periodontal pockets. Adjunctive therapies improve tissue healing through detoxification bactericidal effects. Photodynamic therapy (PDT) is a non-invasive treatment procedure that involves the use of dye as photosensitizer to attach target cell be activated by photon an appropriate wavelength. This study aimed assess effectiveness PDT in treating periodontitis adjunct scaling root planing....

10.34172/joddd.2020.030 article EN cc-by Journal of Dental Research Dental Clinics Dental Prospects 2020-09-21

Background: Current study designed to identify the causes of abnormal uterine bleeding( AUB) in perimenopausal women and also correlate with their histopathological examination.Methods: A prospective 65 complaint AUB age group ranging from 40 1 year within menopause those are attending department gynaecology Narayana Medical College & Hospital, Nellore. Clinical examinations between parameters were analysed. Histopathological examination report was correlated clinical...

10.18203/2320-1770.ijrcog20151277 article EN International Journal of Reproduction Contraception Obstetrics and Gynecology 2015-01-01

The aim of this study was to evaluate the bone regeneration potential concentrated marrow aspirate (BMA)-coated hydroxyapatite (HA) for reconstruction mandibular defects caused by removal benign pathologies.This prospective clinical included ten patients with histopathologically proven pathologies mandible measuring <5 cm anteroposteriorly, who were treated enucleation or marginal resection, followed autologous BMA-coated synthetic biphasic HA (HA and beta-tricalcium phosphate) graft...

10.4103/ccd.ccd_745_18 article EN cc-by-nc-sa Contemporary Clinical Dentistry 2018-01-01

Medical image analysis is recognised to be the most important research area for diagnosis and screening of a wide range medical problems. The commonly discussed diabetic retinopathy has become vital factor serious eye diseases leading blindness. Diabetes mellitus, remarkable metabolic disorder, rapidly increasing health threats worldwide. major cause Diabetic Retinopathy (DR) increase in blood insulin levels. DR lesion thresholds inferred have protective effects no benefits patients. From...

10.1504/ijcat.2020.10034803 article EN International Journal of Computer Applications in Technology 2020-01-01

Introduction: Psoriasis is one of the skin disorder, mainly characterized by scaly papules and plaques. The etiology psoriasis multifactorial still not properly understood. In our study, we tried to elucidate relation between trace elemens namely Zinc, Copper Selenium. Materials Methods: This study enrolled 50 patients with 37 males 13 females, 10- 80 years age. were randomly selected from outpatient clinic Dermatology, Venereology Leprosy Department, Narayana medical college hospital. age,...

10.18231/j.ijced.2019.051 article EN cc-by-nc-sa IP Indian Journal of Clinical and Experimental Dermatology 2019-09-17

Background and Aims- The six minute walk test is widely used as an outcome measure in pulmonary rehabilitation programs. objective of this study to report the magnitude change with repetition patients chronic obstructive disease on program. Methods: A prospective 51 moderate very severe COPD was carried out. Clinical examination, spirometry, distance were done. All advised regular follow up visits at three, twelve months. Results: Four (8%) cases completed all one those showed improvement...

10.3126/jaim.v2i2.8774 article EN Journal of Advances in Internal Medicine 2013-09-29

To address the public health issue of type 2 diabetes (T2D) and its genetic profile in India, we aimed to evaluate determinants T2D using family-based cohorts from four distinct Endogamous Ethnic Groups (EEGs) representing two Northern (Punjab [Sikhs: SI] Rajasthan [Agarwals: AG]) Southern (Tamil Nadu [Chettiars: CH] Andhra Pradesh [Reddys: RE]) states examine whether variants found through targeted sequencing previously established 8 South Asian risk loci (including one Sikh population) are...

10.2337/db19-1717-p article EN Diabetes 2019-06-01

Objective: The study is aimed to analyze endothelial progenitor cells (EPCs) in coronary artery disease and also identify predictive marker assess EPCs the same condition. Background: Endothelial (EPC) predict morbidity mortality cardiovascular risk. ideal way cure atherosclerosis subsequent end organ damage restore rejuvenate dysfunctional vasculature by induction of EPCs. Methods Results: characterized CD34 KDR or CD133 markers still progress standardize. Hence, current demonstrates EPC...

10.5530/jcdr.2016.1.4 article EN Journal of Cardiovascular Disease Research 2016-03-17

Wharton’s jelly (WJ) is a gelatinous tissue exists in the umbilical cord contains stromal cells, termed as mesenchymal cells (MSCs). Current study designed to characterize stem cell population both within blood and it’s wharton’s correlation neonatal parameters. Both their CD34+ CD90+ expression was enumerated by flow-cytometry. Neonatal parameters along with mode of delivery were analyzed correlate CD34 CD90 markers. From total 20 deliveries, pattern showed varied samples. Gender markers...

10.5455/jabet.2018.d7 article EN cc-by Journal of Advanced Biotechnology and Experimental Therapeutics 2018-01-01

Introduction: Vascular endothelial cell senescence has been involved in dysfunction and inflammation promotes atherosclerosis; moreover, vascular cells with senescent phenotype have found the human atherosclerotic plaques. The mechanism of through telomere length (TL) shortening explained but, reference to micronutrient status, was not fully clarified. To our knowledge, there is no study on level telomere/telomerase combination levels coronary artery disease (CAD). Methods: Twenty patients...

10.4103/bbrj.bbrj_117_18 article EN cc-by-nc-sa Biomedical and Biotechnology Research Journal (BBRJ) 2018-01-01
Coming Soon ...