A5087674609- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Vectors
- Virology and Viral Diseases
- Viral gastroenteritis research and epidemiology
- interferon and immune responses
- Viral Infections and Outbreaks Research
- Vaccine Coverage and Hesitancy
- Immune Cell Function and Interaction
- Mosquito-borne diseases and control
- Animal Virus Infections Studies
- Poxvirus research and outbreaks
- Herpesvirus Infections and Treatments
- Bacillus and Francisella bacterial research
- Respiratory viral infections research
- Cytokine Signaling Pathways and Interactions
- Virus-based gene therapy research
- Influenza Virus Research Studies
- Immunodeficiency and Autoimmune Disorders
Rosalind Franklin Institute
2022-2023
Pandemics in the last two centuries have been initiated by causal pathogens that include Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (e.g., H1N1 pandemic of 2009). The latter is considered to prior pandemics 1918 1977, known as “Spanish Flu” “Russian Flu”, respectively. Here, we discuss other emerging infections could be potential public health threats. These Henipaviruses, which are members family Paramyxoviridae infect bats mammals. also Parainfluenza Mumps viruses (Rubulavirus)...
Ebola virus (EBOV) is a zoonotic comprising of six known different species, designated within the family Filoviridae and genus Ebolavirus. The first recorded outbreak an EBOV disease (EVD) was in Yambuku, Zaire (ZEBOV) 1976, followed by Sudan (SUDV) later that year. Outbreaks have been increasing throughout 21st century, mortality rates can reach up to 90%. Such extraordinary virulence evidenced few pathogens, similar Marburg (MARV) originated Uganda detected Germany 1967. virulent nature...
Since 2019, notable global viral outbreaks have occurred necessitating further research and healthcare system investigations. Following the coronavirus disease 2019 (COVID-19) pandemic, in 2022, whilst severe acute respiratory syndrome 2 (SARS-CoV-2) strains evolved, monkeypox virus (MPXV) infections became more evident. MPXV is of Orthopoxviridae genus, belonging to family Poxviridae. Zoonotic transmission (animal-to-human transmission) may occur. The genus includes other orthopoxviruses...
Interferons (IFNs) were the original prototype cytokine system discovered in 20th century research. As name interferon implies (derived from Latin interfere-on), these proteins have immunostimulatory, primarily antiviral and antitumour properties are synthesised secreted between cells. Due to technological advances, processes variable factors involved IFN regulation can be comparatively explained by expressed genes expressed. In this review, we provide a brief introduction background on...
Measles virus (_Morbillivirus_ abbreviated as MV, but more recently MeV) is the causal agent of disease, thought to have existed at least 4000 years ago, affecting predominantly infants, also immunocompromised individuals and others remaining a public health issue today globally. In this review, we are discussing historical background about MeV infection modern–day research, then delving into disease what known immunisation against disease. We elucidate viral structure function proteins. The...
Measles virus (Morbillivirus abbreviated as MV, but more recently MeV) is the causal agent of measles disease, thought to have existed at least 4,000 years ago, affecting predominantly infants, also immunocompromised individuals remaining a public health issue today globally. In this review, we discuss historical background about MeV infection modern-day research on current epidemiology, what known immunisation against it. We report viral structure and function proteins. This additionally...
Since 2019, notable global viral outbreaks have occurred necessitating further research and healthcare system investigations. Following the COVID—19 pandemic, an unexpected duality has of SARS–CoV–2 monkeypox virus (MPXV) infections. Monkeypox is Orthopoxviridae genus, belonging to family Poxviridae. Zoonotic transmission (animal human transmission) may occur. The genus includes other Orthopoxviruses (OPXV) present in animal host reservoirs that include cowpox...
Interferons were the original prototype cytokine system discovered in 20th-century research. As name implies, they originally thought to be synthesised and secreted between cells. Thanks technological advances, processes involved protein secretion can explained comparatively more clearly at both genetic biochemical levels. The discovery of interferon (IFN) occurred when research was still its infancy. Franklin Wilkins structure function deoxyribonucleic acid (DNA) same time as Crick Watson;...
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-stranded RNA (ssRNA) severe acute respiratory syndrome 2 (SARS-CoV-2). However, other human coronaviruses (hCoVs) exist, of which Middle East Respiratory Syndrome (MERS) and SARS-CoV (SARS) showed higher mortality rates without causing pandemic. As December 2022, SARS-CoV-2 has resulted in over 6.6 million deaths worldwide through an array to chronic pathologies. Historical pandemics include smallpox influenza...
Ebola virus is a zoonotic comprised of 6 different species designated within the family Filo-viridae and genus Ebolavirus. The first recorded outbreak an (EBOV) was in Yambuku, Zaire (ZEBOV) 1976, followed by Sudan (SUBOV) later that year. Outbreaks have been increasing throughout 21st century, mortality rates can reach up to 90%. Such extraordinary virulence evidenced with few pathogens, similarly Marburg (MARV) originated Uganda detected Germany 1967. virulent nature filovirus disease has...