A5016443996- Atherosclerosis and Cardiovascular Diseases
- Cancer Diagnosis and Treatment
- Ubiquitin and proteasome pathways
- Traditional Chinese Medicine Studies
- Peptidase Inhibition and Analysis
- Cancer, Lipids, and Metabolism
- Ferroptosis and cancer prognosis
- Traditional Chinese Medicine Analysis
- Prostate Cancer Treatment and Research
- Phagocytosis and Immune Regulation
- Congenital Anomalies and Fetal Surgery
- Extracellular vesicles in disease
- PARP inhibition in cancer therapy
- Management of metastatic bone disease
- Renal and Vascular Pathologies
- Nephrotoxicity and Medicinal Plants
- Caveolin-1 and cellular processes
- Acute Myocardial Infarction Research
- Chronic Kidney Disease and Diabetes
- Autophagy in Disease and Therapy
- Cell death mechanisms and regulation
- Head and Neck Surgical Oncology
- Hepatocellular Carcinoma Treatment and Prognosis
- Atrial Fibrillation Management and Outcomes
- Microbial Natural Products and Biosynthesis
Guiyang Medical University
2022-2025
Zunyi Medical University
2024
Zhejiang University
2024
Wenzhou Medical University
2017-2023
Dongyang People's Hospital
2017-2023
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2021-2022
Shanghai University of Traditional Chinese Medicine
2021-2022
Beijing Anzhen Hospital
2014-2015
Capital Medical University
2014-2015
Red Cross Hospital
2015
This study aimed to explore the role of lactoferrin (LTF) in atherosclerosis (AS) and its possible mechanisms. Human left coronary artery tissues were collected divided into control (CON), heart disease (CHD) sudden death (SCD) groups. Pathologic changes (including plaque area, necrotic core, collagen fibers, foam cell content) observed. The LTF, P62, 4-hydroxynonenal (4-HNE) expression levels assessed. ApoE–/– AS mouse model was established. pathological related protein analyzed after...
Endogenous retroviruses (ERVs) are ancient retroviral remnants integrated in host genomes, and commonly deleted through unequal homologous recombination, leaving solitary long terminal repeats (solo-LTRs). This study, analysing the genomes of 362 bird species their reptilian mammalian outgroups, reveals an unusually higher level solo-LTRs formation birds, indicating evolutionary forces might have purged ERVs during evolution. Strikingly order Passeriformes, especially parvorder Passerida,...
Lung cancer is the leading cause of deaths in China, and about 60% cases are diagnosed with histological adenocarcinoma. The caspase 8 (CASP8) gene a critical initiator extrinsic apoptosis pathway. To explore relationship between tagSNPs or haplotypes CASP8 efficacy platinum-based chemotherapy advanced lung adenocarcinoma patients we recruited 555 patients. We extracted genomic DNA from patients' peripheral blood samples sequenced CASP8. calculated individual haplotype frequencies using...
Abstract Background: Ubiquitin-specific protease 18 (USP18), is a member of the ubiquitin-specific family. Previous studies have shown that USP18 expression upregulated in patients with heart failure and considered as novel target for treatment failure. However, role atherosclerosis remains unclear. In this study, we aimed to investigate pattern its relationship between extent atherosclerotic cholesterol transporter protein ABCG1. Methods: GSE6054 dataset was obtained from Gene Expression...
Abstract Background Ubiquitin-specific protease 18 (USP18), also known as UBP43, is a member of the ubiquitin-specific family involved in suppressing viral activity and promoting tumor migration. Previous studies have shown that USP18 expression upregulated patients with heart failure considered novel target for treatment failure. However, role atherosclerosis remains unclear. In this study, we sought to explore on ATP-binding cassette transporter protein G1 (ABCG1)-dependent cholesterol...
Objective: The study aims to investigate the effect of DEL-1 expression in atherosclerotic plaque formation and its mechanism.Methods: Human left coronary arteries were collected detect expression. ApoE-/- mice used establish atherosclerosis model. artery mouse aorta stained with HE, Oil Red O, Movat staining. levels, chemokines CXC chemokine receptor 4 (CXCR4) ligand stromal cell-derived factor-1alpha (SDF-1α), pathway protein glycogen synthase kinase-3β (GSK-3β), CCAAT enhanced binding β...