A5101876198- Oral Health Pathology and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Meningioma and schwannoma management
- Cancer-related molecular mechanisms research
- Dental Radiography and Imaging
- Oral and Maxillofacial Pathology
- Semiconductor Lasers and Optical Devices
- Cancer Immunotherapy and Biomarkers
- Extracellular vesicles in disease
- Vascular Malformations Diagnosis and Treatment
- Immune Cell Function and Interaction
- Glioma Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Head and Neck Cancer Studies
- Photonic and Optical Devices
- RNA modifications and cancer
- Advanced Fiber Laser Technologies
- Intracranial Aneurysms: Treatment and Complications
- Nonlinear Optical Materials Studies
- Neurofibromatosis and Schwannoma Cases
- Circular RNAs in diseases
- Temporomandibular Joint Disorders
- Medical Imaging Techniques and Applications
- Semiconductor Quantum Structures and Devices
- Intracerebral and Subarachnoid Hemorrhage Research
Central South University
2008-2024
Sichuan University
2019-2024
West China Hospital of Sichuan University
2019-2024
Xiangya Hospital Central South University
2007-2023
Stomatology Hospital
2005-2020
Weatherford College
2019
Zhejiang University
2005-2016
Second Affiliated Hospital of Harbin Medical University
2014
Harbin Medical University
2014
National Institute of Neurological Disorders and Stroke
2013
Abstract The adipogenic differentiation of adipose tissue‐derived mesenchymal stem cells (ADSCs) is a critical issue in many obesity‐related disorders. Cytidine‐cytidine‐adenosine‐adenosine‐thymidine (CCAAT) enhancer binding protein α (CEBP‐α) and peroxisome proliferator‐activated receptor‐γ are two important lipogenic transcription factors markers differentiation. Noncoding RNAs participate long noncoding RNA (lncRNA) H19 related to multiple cellular differentiation, including...
Abstract Oral submucous fibrosis (OSF) is a high-risk precancerous condition of the oral cavity. Areca nut chewing its key etiologic factor, but full pathogenesis still obscure. In this study, microarray analysis was used to characterize mRNA changes 14,500 genes in four OSF and normal buccal mucosa samples identify novel biomarkers OSF. Five candidate with most differential were chosen for validation. The correlation between clinicopathologic variables 66 patients expression each gene...
Lymphocyte infiltrates have been observed in the microenvironment of oral cancer; however, little is known about whether immune response lymphocyte infiltrate affects tumor biology. For a deeper understanding role infiltrating-lymphocytes squamous cell carcinoma (OSCC), we characterized repertoires and defined their features. Immunohistochemistry revealed considerable T B lymphoid follicles with germinal center-like structures within microenvironment. Flow cytometry demonstrated that...
Glioblastoma (GBM) is the most malignant tumor in human brain. High invasiveness of this main reason causing treatment failure and recurrence. Previous study has found that LACTB a novel suppressor breast cancer. Moreover, function other tumors mechanisms involving were also reported. However, role relevant GBM invasion remains to be revealed. Our aim investigate migration invasion. We was downregulated gliomas compared normal brain tissues. Overexpression suppressed LN229 U87 cell lines....
We summarize the linear and nonlinear optical properties of a variety CdTe CdS quantum dots in glass. The measured absorption sample is compared with calculations involving valence-band mixing due to confinement. temperature dependence lowest quantum-confined transition its linewidth for samples various crystallite sizes are simple model. It found that shift energetically as function same temperature-dependent band-gap reduction bulk materials. Excitation pulses ranging from femtoseconds...
The characteristics of fibrosis include the abnormal accumulation extracellular matrix proteins and tissue repair caused by injury, infection, inflammation, leading to a significant increase in organ failure mortality. Effective precise treatments are urgently needed halt reverse progression fibrotic diseases. Exosomes tiny vesicles derived from endosomes, spanning 40 160 nanometers diameter, which expelled into environment various cell types. They play crucial role facilitating cell-to-cell...
Oral submucous fibrosis (OSF) is a chronic and inflammatory mucosal disease caused by betel quid chewing, which belongs to oral potentially malignant disorders. Abnormal fibroblast differentiation leading disordered collagen metabolism the core process underlying OSF development. The epithelium, first line of defense against external environment, can convert signals into pathological participate in remodeling fibrotic microenvironment. However, specific mechanisms epithelium drives remain...
The emission linewidth above threshold is measured in a GaAs/AlGaAs microcavity surface-emitting laser with single cavity mode. broadening factor good agreement theoretical calculations that include the most important many-body Coulomb effects of electron-hole plasma.
The establishment of adaptive immune responses to neoplasms involves not only the tumour tissue, but also peripheral blood. We aimed conduct a preliminary exploration understand response T lymphocytes blood mononuclear cells (PBMC-Ts) in oral squamous cell carcinoma (OSCC).A total 103 samples from OSCC patients and 18 healthy donors (HD) were analysed by flow cytometry.Compared those HD, series unique features PBMC-Ts observed including significant increase CD4+ cells, shift naïve...
We have studied femtosecond pulse propagation in CdS quantum-dot-doped waveguides produced by the solgel and ion-exhange methods. The observed two-photon absorption asymmetric spectral modulation of transmitted pulses are explained our theoretical model, which incorporates a near-resonant transition.
summary The aim of this investigation was to study the remodelling cartilage in mandibular condyle following disc displacement (DD) temporomandibular joint (TMJ). Forty adult Japanese white rabbits were used study. right joints 28 40 had their discs surgically displaced. Four killed at 4 days or 1, 2, 4, 6, 8 and12 weeks after surgery. messenger RNA (mRNA) expression levels aggrecan and type II collagen cartilages measured using situ hybridization techniques. Results showed that mRNA reduced...