- Oral Health Pathology and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Oral and Maxillofacial Pathology
- Head and Neck Cancer Studies
- Cleft Lip and Palate Research
- Reconstructive Facial Surgery Techniques
- Cancer Diagnosis and Treatment
- Dental Implant Techniques and Outcomes
- Facial Nerve Paralysis Treatment and Research
- Periodontal Regeneration and Treatments
- Immune Cell Function and Interaction
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Tracheal and airway disorders
- Dental materials and restorations
- Genetic factors in colorectal cancer
- Tumors and Oncological Cases
- Oral microbiology and periodontitis research
- Proteoglycans and glycosaminoglycans research
- Orthodontics and Dentofacial Orthopedics
- Facial Trauma and Fracture Management
- Salivary Gland Disorders and Functions
- Laser Applications in Dentistry and Medicine
- Immunotherapy and Immune Responses
- Cancer Immunotherapy and Biomarkers
Xiangya Hospital Central South University
2010-2021
Central South University
2012-2021
Hainan General Hospital
2016
National Medical Research Center of Dentistry and Maxillofacial Surgery
1994-2008
Sichuan University
2007
Changsha Medical University
1999
A random sample of 119 young, healthy Han Chinese adults (56 men and 63 women) between the age 18 25 years (mean, 22.7 y) in PR China was obtained for this study. By guidance standard methods, based on Farkas's anthropometric measurements craniofacial region, 12 nasal soft tissue landmarks linear 3 angular were chosen. The taken directly, whereas by photogrammetric method. Eight proportion indices calculated according to measurements. application independent-samples t-test showed sex...
The aim is to measure and investigate the anatomic structures of orbital soft tissue relationships between adjacent regions in 102 normal young Han Chinese adults using a computer-assisted photography system provide reference data for periocular cosmetic reconstructive surgery.A random sample (53 males 49 females) aged from 18 25 years Changsha, Hunan Province, was obtained. Standard digital images were taken then processed Image-Pro Plus 6.0 software. linear angular measurements, including...
The anterolateral thigh flap has been the workhouse for coverage of soft-tissue defects in head and neck decades. However, reconstruction multiple complex with multipaddled chimeric flaps is still a challenge reconstructive surgeries. Here, clinical series 12 cases reported which were used several separately anatomic locations neck. Of cases, 7 patients presented trismus diagnosed as advanced buccal cancer oral submucous fibrosis, 2 tongue found accompanied mucosa lesions or cancer, 3...
Abstract Oral submucous fibrosis (OSF) is a high-risk precancerous condition of the oral cavity. Areca nut chewing its key etiologic factor, but full pathogenesis still obscure. In this study, microarray analysis was used to characterize mRNA changes 14,500 genes in four OSF and normal buccal mucosa samples identify novel biomarkers OSF. Five candidate with most differential were chosen for validation. The correlation between clinicopathologic variables 66 patients expression each gene...
To introduce and evaluate the clinical effects of digital surgical guide plate technology in combined osteotomy reconstruction pre-bent position (CORPPP) technique during mandibular segmental resections.Seven cases resection with simultaneous vascularized free fibula flap by oral maxillofacial surgery were selected (Xiangya Hospital, Changsha, China; June 2015 through December 2015). Cone-beam computed tomographic (CBCT) spiral CT scans mandibles fibular donor sites, respectively, collected....
For buccal squamous cell carcinoma (SCC) patients accompanied with severe oral submucous fibrosis (OSF), it is a challenge to simultaneously reconstruct bilateral defects created from cancer resection and contralateral OSF release improve postoperative mouth opening. Herein, we present case of reconstruction in 46-year-old patient who had left SCC OSF. Extensive ablation involved the full-thickness cheek as well part mandible right tissue were performed. A tripaddled anterolateral thigh...
The current research concerns the clinicopathological significance of MHC class I chain-related protein A (MICA) expression in oral squamous cell carcinomas (OSCCs). and location MICA 14 normal mucous 45 cancerous para-cancerous tissues were assessed by immunohistochemistry levels mRNA 29 determined real-time polymerase chain reaction. Data analyzed with SPSS16.0 software package. was found to be located cytoplasm plasma membrane. Expression higher than (P < 0.05). However, no statistical...
This study was conducted to investigate the effect of chewing fresh or dried betel nut on inci-dence and canceration oral mucosa disease in Haikou City Hainan Province.Through a survey questionnaire, clinical examination, regular follow-up, we collected data from 1 722 cases divided them into two groups, among which 704 afflicted people chew nut, whereas other 018 nut. The were statistically analyzed using different variables included age, number, time onset disease, cancerous condition...
Chronic lip discoid lupus erythematosus (DLE) is a potentially malignant disorder that can develop into squamous cell carcinoma (LSCC). Podoplanin specific marker for lymphatic endothelial cells and plays role in cancer progression. The objective of this study was to determine the immunoexpression podoplanin samples patients with DLE its correlation risk progression LSCC. In retrospective study, expression determined using immunohistochemistry from 52 DLE, including 44 untransformed 8...