- Antifungal resistance and susceptibility
- Creativity in Education and Neuroscience
- Infectious Diseases and Mycology
- Design Education and Practice
- Diabetes Management and Research
- Disaster Response and Management
- Engineering Education and Technology
- Pregnancy and Medication Impact
- Educational Innovations and Challenges
- Chronic Kidney Disease and Diabetes
- Preterm Birth and Chorioamnionitis
- Respiratory viral infections research
- Urban and spatial planning
- Frailty in Older Adults
- Pneumonia and Respiratory Infections
- Clostridium difficile and Clostridium perfringens research
- Hepatitis C virus research
- Mycobacterium research and diagnosis
- Hepatitis B Virus Studies
- Assisted Reproductive Technology and Twin Pregnancy
- Health Systems, Economic Evaluations, Quality of Life
- Fungal Infections and Studies
- Chronic Disease Management Strategies
- Diabetes Treatment and Management
- Liver Disease Diagnosis and Treatment
Kyoto University
2023-2024
The University of Tokyo
2020-2023
Health Economics and Outcomes Research (United Kingdom)
2020
Saitama University
2002-2003
ABSTRACT Objective The global prevalence of nontuberculous mycobacterial pulmonary disease (NTM‐PD) has been steadily increasing. A few small retrospective studies have reported a poor prognosis associated with chronic aspergillosis (CPA) as complication NTM‐PD. Furthermore, the prognostic impact CPA may inadequately assessed due to differences in background factors. This study aimed identify risk factors for NTM‐PD and compare in‐hospital mortality between patients without aspergillosis....
Abstract Background The administration of broad-spectrum antimicrobials has prevailed in the clinical management community-onset pneumonia (COP). Growing evidence suggests that use unnecessary for patients with COP leads to adverse events and poor outcomes. This study aims understand impact antipseudomonal β-lactam on outcomes resource utilization hospitalized a low risk drug-resistant pathogens (DRPs). Methods historical cohort analyzed hospital claims database Japan from January December...
Objective To describe the prevalence of multimorbidity and its associations with clinical outcomes across age groups. Design Retrospective cohort study using nationwide medical claims data. Setting Carried out in Japan between April 2014 March 2019. Participants N=246 671 Japanese individuals aged 20–74 enrolled health insurance were included into baseline data set for fiscal year (FY) 2014. Of those, N=181 959 spanning FY2014–FY2018. Exposures Multimorbidity was defined as having ≥2 15...
Although patients with HBV have a risk of reactivation after immunosuppressive therapy (IST), the status their management is unclear in Japan. This study aims to describe proportion who received preventive during ISTs chronic infection HBsAg or resolved infection.
To evaluate whether sodium-glucose cotransporter 2 inhibitor (SGLT2i) therapy is associated with a reduction of renal events compared other glucose-lowering drugs (oGLDs) among Japanese people type diabetes (T2D) and grade 3 (G3) chronic kidney disease (CKD) in real-world clinical practice setting.
Abstract We evaluated the teratogenic risk associated with exposure to cefditoren pivoxil during first trimester of pregnancy using integrated databases Toranomon Hospital and National Center for Child Health Development. Among 13 599 registered individuals, analysis included 285 subjects who had taken pregnancy. The rates stillbirth, miscarriage, elective terminations were 0.4%, 5.6%, 2.1%, respectively. 262 live births, preterm birth, low birth weight, major congenital malformations 4.6%,...
Despite the ongoing efforts to refine treatment durations and methods for patients with chronic pulmonary aspergillosis, clinical use of antifungal agents remains unclear. This study aimed describe practices, trajectories, prognoses newly diagnosed aspergillosis. Data from a longitudinal database hospitals in Japan was used. The target population included who started following their initial diagnosis aspergilloma, or necrotizing aspergillosis between October 2015 September 2017. We described...
Background: In Japan, the numbers of confirmed COVID-19 cases and deaths (13·45 0·726 per 100,000 residents, respectively) are far less than those other developed countries in Europe US. However, would not capture entire disease burden COVID-19. Our objective was to estimate overall excess mortality Japan during pandemic, or March April 2020, using data from local government. Method: Vital statistic 13 populous cities (Total population: 22·4 Millions) one comparator city where no Covid-19...
This research has examined the need of "the high creativity object" which should be necessary for future global society. And, this been defined as universally diachronic power it proved scientifically. It is said that value talented people who have can produce an original thing generally high. As in research, was expressed quantitatively. Creativity goes along characteristic, and isn't indicated system from thing. because very objective numerical doesn't change even if ポpossibility depends...
This research has examined the need of "the high creativity object" which should be necessary for future global society. And, this been defined as universally diachronic power it proved scientifically. Four stages are set up about expression by newly. is thought stage to common even in field. It gives outline process stated before report. And point was useful comparison with until now in. found out that result some points. As utility well, report reported.
Need toward the higher creativity is being shouted in recent society. But, "creativity" with still an abstraction and not established concretely vague. So, next thing written this paper. About establishment of definition "the creativity" to try by research, "creative engineering", (1) Verification that need meaning. (2) How does research contribute future engineering field? Some examples are taken up, it proposed about these.