Introduction: The burden of disease measures the total impact diseases on a population, considering incidence, prevalence, disability, and premature mortality. This study analyzes ischemic heart (IHD) in Tabasco, Mexico, from 2013 to 2021. Ischemic has significant incidence 21,203,479.22 cases worldwide, nationally (inside Mexico) with 221,747.28 cases, more than 9,137,791 deaths due this pathology globally. Objective: To analyze during 2013-2021. Methods: An observational, descriptive,...

Introducción: El Acceso Vascular es necesario en hemodiálisis para el paciente con ERC avanzada, la infección causa más común de morbilidad y segunda mortalidad. Objetivo general Determinar tipo acceso vascular que incrementa riesgo ITS pacientes HD del H.G. Z No. 46. Material métodos: Lugar estudio: H.G.Z 46; Diseño Observacional, analítico, cohorte, retrospectivo, retrolectivo. Temporalidad: 01 enero 2017 al 31 diciembre 2022. Muestra: 83 presentaron ITS. Tipo muestreo: No probabilístico...

Introduction: The burden of disease measures the total impact diseases on a population, considering incidence, prevalence, disability, and premature mortality. This study analyzes ischemic heart (IHD) in Tabasco, Mexico, from 2013 to 2021. Ischemic has significant incidence 21,203,479 cases worldwide, nationally (inside Mexico) 221,747 cases, with more than 9,137,791 deaths due this pathology globally. Objective: To analyze during 2013–2021 period. Methods: An observational, descriptive,...

The COVID-19 pandemic is currently a worldwide threat and concern, not only because of itself but its sequelae. aim this study was to evaluate whether relation between COVID-19, Long COVID, the prevalence mental health disorders exist. A total 203 people from Tabasco were included in study, answering survey integrated by three dominions: General epidemiological data, DASS-21 test (to determine presence signs or symptoms suggestive depression, anxiety, and/or stress) an exploratory...

Background Due to the wide spread of SARS-CoV2 around world, risk death in individuals with metabolic comorbidities has dangerously increased. Mexico a high number infected and deaths by COVID-19 as well an important burden diseases; nevertheless, reports about features Mexican are scarce. The aim this study was evaluate demographic features, clinical characteristics pharmacological treatment who died south Mexico. Methods We performed observational including information 185 deceased...

Transient receptor potential ankyrin 1 (TRPA1) is a non-selective cation channel expressed by subset of nociceptive neurons that acts as multimodal receptor. Its activity contributes to modulate transmission in acute inflammatory pain. However, the role this chronic pain has been less studied. The purpose study was investigate local peripheral and spinal participation TRPA1 channels formalin-induced long-lasting hypersensitivity.Formalin (1%)-induced hypersensitivity determined application...

This study aimed to evaluate the effect of early time-restricted eating (eTRE) on metabolic markers and body composition in individuals with overweight or obesity. Seventeen subjects completed a randomized, crossover, controlled clinical trial. Twelve women five men participated, mean age 25.8 ± 10.0 years BMI 32.0 6.3 kg/m2. The eTRE intervention included 16 h fasting (3:00 pm 7:00 am) 8 ad libitum (7:00 am 03:00 pm) (16:8). trial four weeks interventions followed by four-week washout...

Intracellular pH is a fundamental parameter to cell function that requires tight homeostasis. In the absence of any regulation, excessive acidification cytosol would have tendency produce cellular damage. Mammalian Na + /H exchangers (NHEs) are electroneutral -dependent proteins exchange extracellular for intracellular H . To date, there 9 identified NHE isoforms where NHE1 most ubiquitous member, known as housekeeping exchanger. seems protective role in ischemia-reperfusion injury and other...

Abstract Latent autoimmune diabetes in adults (LADA) has clinical and metabolic features of type 1 2 diabetes. LADA does not have specific for its diagnosis apart from autoantibody detection; however, these tests are affordable settings . In this cross-sectional study, we analyzed criteria, control, pharmacological treatment, diabetic complications two groups patients with -LADA T2D- order to identify characteristic entities. Finally, evaluated if the estimated glucose disposal rate (eGDR)...

It is accepted that there a genetic factor influences the risk of suicidal behavior. The catechol-O-methyltransferase (COMT) gene, especially Val108/158Met polymorphism, has been associated with suicide; however, no conclusive outcome attained. Therefore, aim present study was to assess role COMT in behavior throughout an updated meta-analysis.We performed online search using PubMed and Web Science (up March 2017). Our systematic review included case-control studies individuals who attempted...

Vaccinations have helped to control the COVID-19 pandemic; however, few studies focus on adverse effects and allergic reactions of these vaccines fewer a scope in Latin American population. The objective this study was assess associations between vaccinations, sex, age, reactions, effects. This an analytical cross-sectional conducted 1 July October 2022. sample consisted 443 surveyed participants, with total 1272 vaccine doses. Seven (Pfizer BioNTech, Oxford-AstraZeneca, CanSino, Moderna,...

Mental health disorders are relatively common in the general population and were already an important issue for healthcare sector before COVID-19. COVID-19, being a worldwide crucial event evidently great stressor has increased both prevalence incidence of these. Therefore, it is evident that COVID-19 mental closely related. Moreover, several coping strategies exist to endure said such as depression anxiety, which used by confront stressors, workers not exception. This was analytical...

The aim of this case-control study was to explore the association by gender between HTR2C gene variants and suicidal behavior in a Mexican population.A total 183 suicide attempters 208 healthy volunteers were included study. We genotyped five polymorphisms (rs547536, rs2192372, rs4272555, rs6318, rs2428707), then measured genotype, allele, haplotype.In female group, we found an two (rs4272555 rs2428707) attempts. C allele single-nucleotide polymorphism (SNP) rs4272555 associated with...

ABSTRACT Preclinical Research Metformin‐dependent mechanisms have been implicated in the antinociceptive effect of some non‐steroidal anti‐inflammatory drugs (NSAIDs). In this study, local peripheral or systemic administration metformin on antinociception induced by indomethacin, ketorolac and metamizole was assessed rat carrageenan‐induced thermal hyperalgesia model. Rats were injected with carrageenan (1%, 50 µl) into right hindpaw which reduced paw withdrawal latency, a measure...

Background: Circulating cell-free mitochondrial DNA (cf-mtDNA) fragments in blood plasma have been reported patients with schizophrenia (SZ). Although the relationship of cf-mtDNA to cognitive status SZ has not yet explored, it is known that impairment compromises functional and social capacity these diminishes their quality life. In this sense, assessment severity a Mexican population its association levels may provide possibility using as biomarker determine disease possible ensuing...

Objetivo: conocer el efecto de una intervención educativa sobre los parámetros bioquímicos pacientes diabéticos usuarios un servicio médico institucional. Métodos: estudio cuasiexperimental, se estudió muestra 25 sujetos con diagnóstico diabetes mellitus tipo 2 (dm2), servicios médicos la Universidad Juárez Autónoma Tabasco. Se realizó evaluación antes y obtuvieron datos demográficos, clínicos bioquímicos. impartieron pláticas grupales mensuales entrega individual material informativo dm2 su...