A5041447283- Lipoproteins and Cardiovascular Health
- Asymmetric Synthesis and Catalysis
- Atrial Fibrillation Management and Outcomes
- Folate and B Vitamins Research
- Acute Myocardial Infarction Research
- Health and Lifestyle Studies
- HIV/AIDS drug development and treatment
- Organic Chemistry Cycloaddition Reactions
- Drug Transport and Resistance Mechanisms
- Molecular spectroscopy and chirality
- Antiplatelet Therapy and Cardiovascular Diseases
- Liver Diseases and Immunity
- Cardiac Arrhythmias and Treatments
- Cardiac Health and Mental Health
- Surgical site infection prevention
- Receptor Mechanisms and Signaling
- Chemical Reactions and Mechanisms
- Cardiovascular Health and Risk Factors
- Axial and Atropisomeric Chirality Synthesis
- Genetic Associations and Epidemiology
- COVID-19 and Mental Health
- Adipokines, Inflammation, and Metabolic Diseases
- Trypanosoma species research and implications
- Phosphorus compounds and reactions
- Organic and Inorganic Chemical Reactions
Universidad Juárez Autónoma de Tabasco
2012-2025
Instituto Nacional de Cardiología
2010-2016
Hospital Regional de Alta Especialidad del Bajío
2012-2015
Center for Rheumatology
2015
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2014
Instituto Nacional de Cardiologia
2012
Center for Research and Advanced Studies of the National Polytechnic Institute
2011
Universidad de Extremadura
1995-2008
Introduction: The burden of disease measures the total impact diseases on a population, considering incidence, prevalence, disability, and premature mortality. This study analyzes ischemic heart (IHD) in Tabasco, Mexico, from 2013 to 2021. Ischemic has significant incidence 21,203,479.22 cases worldwide, nationally (inside Mexico) with 221,747.28 cases, more than 9,137,791 deaths due this pathology globally. Objective: To analyze during 2013-2021. Methods: An observational, descriptive,...
Introduction: The burden of disease measures the total impact diseases on a population, considering incidence, prevalence, disability, and premature mortality. This study analyzes ischemic heart (IHD) in Tabasco, Mexico, from 2013 to 2021. Ischemic has significant incidence 21,203,479 cases worldwide, nationally (inside Mexico) 221,747 cases, with more than 9,137,791 deaths due this pathology globally. Objective: To analyze during 2013–2021 period. Methods: An observational, descriptive,...
The amount of epicardial adipose tissue (EAT) around the heart has been identified as an independent predictor coronary artery disease (CAD), potentially through local release inflammatory cytokines. Ethnic differences have observed, but no studies investigated this relationship in Mexican population. objective present study was to evaluate whether a exist between EAT thickness assessed via echocardiography with CAD and adiponectin levels We studied 153 consecutive patients who underwent...
Background: Lipoprotein (Lp(a)) and homocysteine (Hcy) are independent risk factors for coronary artery disease (CAD). Hcy promotes the release of free apo(a) from Lp(a). The high fibrin affinity inhibits plasminogen binding plasmin generation. Hyperhomocysteinemia can result a less active variant methylene tetrahydrofolate reductase (variant C677T). Because C677T genotype is estimated to be present in 32.2% Mexican population, we took advantage this prevalence determine possible...
Background . Thrombin has been implicated as a key molecule in atherosclerotic progression. Clinical evidence shows that thrombin generation is enhanced atherosclerosis, but its role risk factor for coronary burden not proven artery disease (CAD) stable patients. Objectives To evaluate the association between TAT levels and homocysteine presence of diagnosed by angiography patients with CAD. Methods Results We included 95 admitted to Haemodynamics Department, including 63 significant CAD 32...
Influenza vaccination (IV) and Pneumococcus (PV) are recommended for patients with cardiometabolic diseases. This study aimed to evaluate the immunization rate of ambulatory during COVID-19 pandemic in Americas.Electronic surveys were collected from 13 Spanish speaking countries between 15 June July 2020.4216 analyzed. Mean age 60 (±15) years 49% females. Global IV was 46.5% PV 24.6%. Vaccinated older (IV = 63 vs. 58 years; 68 59, p < 0.01) but without gender difference. Vaccination rates...
To investigate possible predictors and prevalence of surgical site infections (SSIs) in a group Mexican patients who underwent open abdominal surgery.This retrospective study included all (N = 755) elective or emergency surgeries from October 2011 to March 2012.Sociodemographic clinical characteristics were collected through preoperative postoperative examinations by the infection surveillance team. The relationship among variables (age, gender, body mass index, comorbidities, smoking habit,...
Atrial Fibrillation (AF) is associated with an increased risk of stroke and systemic embolism. Several studies have suggested that female AF patients could a greater for stroke. There scarce information about clinical characteristics use antithrombotic therapies in Latin American nonvalvular AF.To describe the gender differences characteristics, thromboembolic risk, therapy recruited Mexico, upper middle-income country, into prospective national CARMEN-AF Registry.A total 1423 consecutive...
Background: Coronary artery disease (CAD) is a chronic, inflammatory, and complex associated with vascular risk factors. Nowadays, the coronary calcium (CAC) specific marker of presence extent atherosclerosis. Additionally, CAC predictor future events in asymptomatic individuals diagnosed subclinical atherosclerosis (CAC > 0). In this study, our aim to evaluate participation two polymorphisms PCSK9 gene as genetic markers for developing cardiometabolic factors individuals. Methods: We...
Homocysteine is implicated as an early atherosclerotic promoter, which enhances the smooth muscle cell proliferation and produces free radicals that induce cellular damage. These factors must have a role in progression of atherosclerosis subsequently leads to vascular mineralization.Aim: Identify correlation between plasma concentration total homocysteine amount minerals accumulate aorta patients with atherosclerosis.Methods: We performed cross-sectional study 13 three-vessel coronary artery...
ABSTRACT Preclinical Research Metformin‐dependent mechanisms have been implicated in the antinociceptive effect of some non‐steroidal anti‐inflammatory drugs (NSAIDs). In this study, local peripheral or systemic administration metformin on antinociception induced by indomethacin, ketorolac and metamizole was assessed rat carrageenan‐induced thermal hyperalgesia model. Rats were injected with carrageenan (1%, 50 µl) into right hindpaw which reduced paw withdrawal latency, a measure...
<strong>Background:</strong> Documenting the patterns of oral anticoagulation therapy (OAT) is essential to prevent thromboembolic complications nonvalvular atrial fibrillation (NVAF). <strong>Objective:</strong> To report OAT according age and risk in patients included CARMEN-AF, a nationwide registry NVAF Mexico, an upper middle-income country. <strong>Material methods:</strong> There were 1,423 consecutive =18 years old with at least one factor enrolled CARMEN-AF Registry their regular...
Abstract Background Congenital cardiac diseases are the most frequent congenital malformations. In adult patients, mineralisation of aorta due to cardiovascular disease is very common, but vascular in paediatric cardiopathies a topic less studied. This study shows that children with complex cardiopathy show high degree ascending aorta. can be part failure pathophysiology cardiopathies. Objective The aim this was determine presence and samples descending Design We conducted cross-sectional...
Abstract The Diels-Alder cycloadditions of 1,3-butadiene and isoprene with D-galacto- D-manno-(E)-nitroalkenes are described. These reactions showed an unlike stereoselectivity, as a consequence the configuration adjacent chiral centre to dienophilic double bond. For adducts, favored regioisomers were those in which nitro methyl groups on cyclohexene rings 1,4-relationship. Assignment absolute configurations at new centres adducts based NMR data polarimetric correlations known compounds.
<h3>Background</h3> Is not uncommon to observe that an important number of patients with rheumatoid arthritis (RA) have withdraw or change treatment because lack loss efficacy. Several mechanisms resistance, including the drug-uptake and drug-efflux transporters belonging superfamily multidrug-resistance (MDR) has been described might explain this status. Among these transporters, ABCB1 (P- gp) ABCG2 (BCRP) may role for among its substrates some disease-modifying drugs such as prednisone...
<h3>Background</h3> ABCB1 (P-gp) and ABCG2 (BCRP1) are part of the adenine triphosphate (ATP)-binding cassette (ABC) transporter proteins. These proteins mediate efflux drugs from inside cells can confer a multidrug resistance phenotype. Drugs included among its substrates indicated in RA patients. Accordingly, an association between disease activity function might be hypothesized. <h3>Objectives</h3> The study was undertaken to compare drug both transporters patients with active inactive...
Introduction:Heart failure in patients with non-valvular atrial fibrillation (NVAF) is two to three times more common than individuals without NVAF.Objective: To identify cardiometabolic risk factors (CMRF) and antithrombotic treatment NVAF heart reduced ejection fraction (HFrEF), determine if there were differences according gender.Methods: CMRF, pro-thrombotic risk, bleeding therapy globally analyzed gender.Results: Out of 1,423 NVAF, 336 had HFrEF.On average, females older males.There was...
Heart failure in patients with non-valvular atrial fibrillation (NVAF) is two to three times more common than individuals without NVAF.To identify cardiometabolic risk factors (CMRF) and antithrombotic treatment NVAF heart reduced ejection fraction (HFrEF), determine if there were differences according gender.CMRF, pro-thrombotic risk, bleeding therapy globally analyzed gender.Out of 1,423 NVAF, 336 had HFrEF. On average, females older males. There was no difference between genders regard...