A5077629563- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Alcohol Consumption and Health Effects
- Diet, Metabolism, and Disease
- Hepatocellular Carcinoma Treatment and Prognosis
- Organ Transplantation Techniques and Outcomes
- Hepatitis C virus research
- Cardiovascular Disease and Adiposity
- Hepatitis B Virus Studies
- Liver Diseases and Immunity
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Cardiovascular Function and Risk Factors
- Cancer, Lipids, and Metabolism
- Colorectal Cancer Surgical Treatments
- Pancreatitis Pathology and Treatment
- Renal Transplantation Outcomes and Treatments
- Diabetes Treatment and Management
- Cardiac Health and Mental Health
- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Lipoproteins and Cardiovascular Health
- Lipid metabolism and disorders
- Innovations in Medical Education
- Diet and metabolism studies
National University Hospital
2020-2025
Kurume University
2024-2025
National University of Singapore
2020-2024
National University Health System
2020-2024
University of Malaya
2024
Ministry of Health
2023-2024
King's College London
2023
Singapore College of Traditional Chinese Medicine
2021-2023
University of California, San Diego
2023
National University Heart Centre Singapore
2022
Milk-derived extracellular vesicles (mEVs) have been proposed as a potential nanomedicine for intestinal disorders; however, their impact on barrier integrity in gut inflammation and associated metabolic diseases has not explored yet. Here, mEVs derived from bovine human breast milk exert similar protective effects epithelial tight junction functionality vitro, survive harsh gastrointestinal conditions ex vivo, reach the colon vivo. Oral administration of restores at multiple levels,...
Background and Aim: The etiology of liver diseases has changed in recent years, but its impact on the comparative burden cancer between males females is unclear. We estimated sex differences across 204 countries territories from 2010 to 2019. Approach Result: analyzed temporal trends using methodology framework 2019 Global Burden Disease study. annual frequencies age‐standardized rates (ASRs) incidence, death, disability‐adjusted life‐years (DALYs) by sex, country, region, disease. Globally...
Emerging data suggest that the incidence of early-onset cancers, defined as cancers diagnosed in people younger than 50 years, is increasing, but updated are limited.To characterize patterns US from 2010 to 2019 and provide granular on with fastest-growing rates.This population-based cohort study analyzed 17 National Cancer Institute Surveillance, Epidemiology, End Results registries January 1, 2010, December 31, 2019. Age-standardized rates per 100 000 were extracted for age adjusted...
The worldwide burden of cancer is increasing in younger populations. However, the epidemiology primary liver remains understudied young adults compared to other forms.
INTRODUCTION: Obesity is associated with cancer, including gastrointestinal (GI). Data from low (LICs) and lower-middle-income countries (MICs) are limited. METHODS: We utilized data the Global Burden of Disease Study 2019 to determine mortality GI cancer risk high body mass index (BMI) in these countries. RESULTS: Mortality rates cancers BMI increased LICs lower MICs, while burdens decreased or remained stable middle-income DISCUSSION: The cancer-related burden necessitating a concerted...
Abstract Food‐derived extracellular vesicles (FEVs) are nanoscale membrane obtained from dietary materials such as breast milk, plants and probiotics. Distinct other EVs, FEVs can survive the harsh degrading conditions in gastrointestinal tract reach intestines. This unique feature allows to be promising prebiotics health oral nanomedicine for gut disorders, inflammatory bowel disease. Interestingly, therapeutic effects of have recently also been observed non‐gastrointestinal diseases....
Summary Backgrounds and Aims Alcohol use leads to disabilities deaths worldwide. It not only harms the liver but also causes alcohol disorder (AUD) heart disease. Additionally, consumption contributes health disparities among different socio‐economic groups. Methods We estimated global regional trends in burden of AUD, disease, cardiovascular disease from using methodology Global Burden Disease study. Results In 2019, highest disability‐adjusted life years rate per 100,000 population was due...