Masahiro Okamoto

ORCID: 0000-0002-8315-347X
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About
Contact & Profiles
Research Areas
  • Microbial Metabolic Engineering and Bioproduction
  • Gene Regulatory Network Analysis
  • Bioinformatics and Genomic Networks
  • Gene expression and cancer classification
  • Semiconductor Quantum Structures and Devices
  • Protein Structure and Dynamics
  • Retinal Diseases and Treatments
  • Biofuel production and bioconversion
  • Semiconductor Lasers and Optical Devices
  • Evolutionary Algorithms and Applications
  • Retinal Imaging and Analysis
  • Quantum and electron transport phenomena
  • Photonic and Optical Devices
  • Glaucoma and retinal disorders
  • Enzyme Catalysis and Immobilization
  • Dialysis and Renal Disease Management
  • Neural Networks and Applications
  • Cancer-related Molecular Pathways
  • Advanced Control Systems Optimization
  • Viral Infectious Diseases and Gene Expression in Insects
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Atomic and Molecular Physics
  • Retinal and Optic Conditions
  • Neural dynamics and brain function
  • Microtubule and mitosis dynamics

Aso Iizuka Hospital
2024-2025

National Hospital Organization Kyushu Cancer Center
2019-2025

University of Fukui
2024

Fukushima Medical University
2019-2024

Ritsumeikan University
2019-2023

University of Tsukuba
2023

Kyushu University
2012-2021

Chiba University
2020-2021

Obayashi (Japan)
2021

Juntendo University Urayasu Hospital
2021

By using array comparative genomic hybridization (CGH), the increased copy number of CYP24 (which encodes vitamin D 24-hydroxylase) at 20q13.2 was previously reported, leading to identification as a candidate oncogene in breast cancer. leads abrogate growth control mediated by D.We examined expression well VDR (vitamin receptor) gene 42 esophageal cancer cases semi-quantitative RT-PCR assay. We induced seven cell lines 25-hydroxyvitamin D3 [25(OH)D3] and compared rate, measured 3-(4,...

10.1093/annonc/mdh056 article EN publisher-specific-oa Annals of Oncology 2004-02-01

Polyvinylalcohol (PVA) hydrogel cross-linked by gamma irradiation was assessed as a possible vitreous substitute. From series of experiments, rise intraocular pressure and inflammatory changes in the cavity after operation were observed some cases. Crab-eating macaques used for this experiment. PVA gels injected into vitrectomy followed clinically opthalmoscopy, tonometry, fundus photography, electroretinogram (ERG), chemotaxis, flare cell meter. Histopathologic examination light electron...

10.1080/02713680600813854 article EN Current Eye Research 2006-01-01

We have fabricated ultranarrow InGaAs/InP buried quantum well wires by means of electron beam lithography and reverse mesa wet etching. Owing to the etching profile, lateral dimension has been reduced 10 nm. Furthermore, we investigated optical characteristics these photoluminescence observed, for first time, clear dependence luminescence wavelength upon wire width even down nm, which is explained theoretical calculation. The blue-shifted shoulder structures were also observed they assigned...

10.1063/1.104526 article EN Applied Physics Letters 1991-02-18

To evaluate the choroidal thickness and blood flow in subfoveal region quantitatively after panretinal photocoagulation (PRP) eyes with severe nonproliferative diabetic retinopathy.This was a prospective comparative study of 24 patients type II diabetes retinopathy no macula edema. The foveal retinal were measured by enhanced depth imaging optical coherence tomography. represented mean blur rate obtained laser speckle flowgraphy. intraocular pressure, pulse rate, hemoglobin A1c level (HbA1c)...

10.1097/iae.0000000000000800 article EN Retina 2015-10-08

Colorectal perforation is associated with high morbidity and mortality rates after surgery. We investigated various clinical features of patients who underwent emergency surgery for colorectal explored the risk factors postoperative complications hospital mortality.

10.23922/jarc.2023-056 article EN cc-by-nc-nd Journal of the Anus Rectum and Colon 2024-04-24

Cholangiocarcinoma (CCC) is relatively hypovascular, in contrast to hepatocellular carcinoma (HCC), which often highly vascular. We investigated if the diminished vascularity of CCC related altered expression thrombospondin–1 (TSP–1), an antiangiogenic factor, and/or vascular endothelial growth factor (VEGF), a potent angiogenic comparing relationships with those high– and low–vascular HCC. also relationship between mutation p53 gene TSP–1 or VEGF expression. Northern blot analysis...

10.1002/hep.510280610 article EN Hepatology 1998-12-01

1 Laboratory for Applied Biological Regulation Technology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyusyu University, 6-10-1 Hakozaki, Higashiku, Fukuoka 812-8581, Japan 2 Institute Basic Medical University Tsukuba, 1-1-1 Tennodai, Ibaraki 305-8575, 3 Bioscience Division, Mitsui Knowledge Industry Co., Ltd, Harmony tower 21th Floor, 1-32-2 Honcho, Nakano-ku, Tokyo 164-8721,

10.11234/gi1990.13.382 article EN Proceedings Genome Informatics Workshop/Genome informatics 2002-01-01

A polarization-insensitive semiconductor optical amplifier was realized at a wavelength of 1.55 mu m. The active layer consisted tensile-strained-barrier multiple quantum well (MQW) structure. At driving current 150 mA, no dependence the saturation characteristics on modes obtained. output power which gain decreases 3 dB is 13.3 dBm. slightly higher 14 dBm measured 200 mA. No large difference observed between transverse-electric (TE) and transverse-magnetic (TM) modes. high 27.5 polarization...

10.1109/68.97840 article EN IEEE Photonics Technology Letters 1991-11-01

To determine the choroidal blood flow and subfoveal thickness (SCT) in eyes with macular edema secondary to branch retinal vein occlusion (BRVO).Thirty-two of 32 patients a BRVO were treated single intravitreal injection ranibizumab (IVR) followed for 2 months. The central SCT, flows evaluated, they compared between recurrent resolved groups.At baseline, SCT was significantly thicker than that fellow eye (P < 0.01). It also group = 0.03). reduction found only after 1 week group. reduced...

10.1097/iae.0000000000001566 article EN Retina 2017-02-24

Signal gain agreement between TE and TM modes is realized under a specific operation condition in traveling wave type amplifier using strained multiple quantum well structure for the first time. The signal of mode completely agrees with that at an driving current 70 mA. identical 7.5 dB present. However, could be easily improved by device longer active region. In order to achieve polarization insensitive TWAs, design parameter only confinement factor conventional bulk type.< <ETX...

10.1109/68.58047 article EN IEEE Photonics Technology Letters 1990-08-01
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