A5002569333- Photodynamic Therapy Research Studies
- Dermatologic Treatments and Research
- Skin Protection and Aging
- Laser Applications in Dentistry and Medicine
- Nanoplatforms for cancer theranostics
- Diagnosis and Treatment of Venous Diseases
- Acne and Rosacea Treatments and Effects
- melanin and skin pigmentation
- Respiratory Support and Mechanisms
- Thermoregulation and physiological responses
- bioluminescence and chemiluminescence research
- Intensive Care Unit Cognitive Disorders
- Wound Healing and Treatments
- Ocular Infections and Treatments
- Fullerene Chemistry and Applications
- Porphyrin and Phthalocyanine Chemistry
- Environmental and Agricultural Sciences
- Immunotherapy and Immune Responses
- Contact Dermatitis and Allergies
- Cancer and Skin Lesions
- Nonmelanoma Skin Cancer Studies
- Sepsis Diagnosis and Treatment
- Hair Growth and Disorders
- Urologic and reproductive health conditions
- vaccines and immunoinformatics approaches
Army Medical University
2016-2025
Southwest Hospital
2016-2025
Nanjing Medical University
2015-2025
Union Hospital
2025
Huazhong University of Science and Technology
2009-2025
Shanghai Fudan Microelectronics (China)
2024
Fudan University
2024
Army Medical College
2024
Binzhou People's Hospital
2005-2024
Heilongjiang University of Chinese Medicine
2016-2024
ABSTRACT Blue light has attracted increasing attention due to its intrinsic antimicrobial effect without the addition of exogenous photosensitizers. However, use blue for wound infections not been established yet. In this study, we demonstrated efficacy at 415 nm treatment acute, potentially lethal Pseudomonas aeruginosa burn in mice. Our vitro studies that inactivation rate P. cells by was approximately 35-fold higher than keratinocytes ( P = 0.0014). Transmission electron microscopy...
Climate-change-induced extreme weather events increase heat-related mortality and health risks for urbanites, which may also affect urbanites' expressed happiness (EH) well-being. However, the links among EH, climate, socioeconomic factors remain unclear. Here we collected ∼6 million geotagged tweets from 44 Chinese prefecture-level cities based on Sina Weibo performed a quadratic regression model to explore relationships between summer heat EH. A three-stage analysis was developed examine...
Abstract: Non-small-cell lung cancer (NSCLC) is one of the leading causes cancer-related death worldwide, and 5-year survival rate still low despite advances in diagnosis therapeutics. A long noncoding RNA (lncRNA) HOX antisense intergenic (HOTAIR) has been revealed to play important roles NSCLC carcinogenesis but detailed mechanisms are unclear. In current study, we aimed investigate regulation between lncRNA HOTAIR p53 patient samples cell lines. Our results showed that expression was...
Epidermal stem cells (EpSCs) that reside in cutaneous hair follicles and the basal layer of epidermis are indispensable for wound healing skin homeostasis. Little is known about effects photochemical activation on EpSC differentiation, proliferation migration during healing. The present study aimed to determine photodynamic therapy (PDT) vivo vitro.We created mouse full-thickness resection models applied 5-aminolevulinic acid (ALA) PDT beds. Wound was analysed by gross evaluation...
Hemoporfin-mediated photodynamic therapy (Hemoporfin-PDT) has been approved for port-wine stain (PWS) in China 2017. This study evaluated the efficacy and safety of Hemoporfin-PDT PWS a real life setting investigated factors that influence efficacy. A multicenter retrospective included patients with who underwent 29 hospitals across completed at least two months follow-up. The was based on patien photographs. total 1679 were included. After first second sessions Hemoporfin-PDT, 63.5 75.3%...
Abstract Background Sarcopenia significantly increases the risk of cognitive impairments in older adults. Early detection mild impairment (MCI) individuals with sarcopenia is essential for timely intervention. Aims To develop an accurate prediction model screening MCI sarcopenia. Methods We employed machine learning and deep techniques to analyze data from 570 patients China Health Retirement Longitudinal Study (CHARLS). Our forecasts incidence over next four years, categorizing into low...
Hepatic fibrosis poses a significant health risk for young adults with type 2 diabetes (T2D). We propose FCFNets, novel factual and counterfactual learning framework to predict hepatic in T2D that can address class imbalance issue increase interpretability leveraging electronic records (EHRs). designed hybrid UNDO oversampling strategy, combining random dissimilar improves dataset diversity model robustness. FCFNets also integrates SHAP-based global instance-level explanations, alongside...
Influenza poses a persistent global health challenge, necessitating innovative approaches to predict host-virus interactions and inform antiviral strategies. Despite advancements, machine-learning-based computational methods typically struggle with limited high-quality negative samples inadequate modeling of complex interactions, which hinder predictive accuracy generalization. To address these challenges, we present SEHI-PPI, novel end-to-end protein-protein interaction (PPI) prediction for...