Alex L. K. Ng

ORCID: 0000-0002-8321-5634
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About
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Research Areas
  • Corneal surgery and disorders
  • Glaucoma and retinal disorders
  • Ophthalmology and Visual Impairment Studies
  • Corneal Surgery and Treatments
  • Retinal Diseases and Treatments
  • Ocular Surface and Contact Lens
  • Intraocular Surgery and Lenses
  • Retinal Imaging and Analysis
  • Ocular Infections and Treatments
  • Mycobacterium research and diagnosis
  • Infectious Diseases and Tuberculosis
  • Ocular Diseases and Behçet’s Syndrome
  • Erythropoietin and Anemia Treatment
  • Diagnosis and treatment of tuberculosis
  • Blood transfusion and management
  • Urticaria and Related Conditions
  • Trauma and Emergency Care Studies
  • Blood donation and transfusion practices
  • Injury Epidemiology and Prevention
  • Medical and Health Sciences Research
  • Cutaneous Melanoma Detection and Management
  • Acne and Rosacea Treatments and Effects
  • Drug-Induced Adverse Reactions
  • Down syndrome and intellectual disability research
  • Olfactory and Sensory Function Studies

University of Hong Kong
2015-2024

Cyberport
2015-2024

Chinese University of Hong Kong
2015-2022

Auckland District Health Board
2021

Golder Associates (China)
2020

Hong Kong Sanatorium and Hospital
2015-2018

University of Wolverhampton
2015-2018

Grantham Hospital
2018

Hong Kong Eye Hospital
2015-2017

Creative Commons
2016

Purpose: We investigate macular perfusion and the systemic ocular associations in a population-based setting. Methods: In this cross-sectional study, 2018 adults residing Hong Kong underwent detailed ophthalmic examinations after consenting to participate. Macular was measured with optical coherence tomography angiography (OCTA) using split-spectrum amplitude decorrelation algorithm. The parafoveal flow index vessel area density were quantified automated custom-built software. Results: Of...

10.1167/iovs.19-28137 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2019-11-20

To compare astigmatic correction between femtosecond-assisted laser in situ keratomileusis (LASIK) and small-incision lenticule extraction (SMILE).A total of 111 patients were included this prospective study. Fifty-seven eyes treated with LASIK 54 SMILE for myopia low to moderate (-0.25 -4.0 D) astigmatism. Uncorrected distance visual acuity (UDVA), corrected manifest refraction measured preoperatively at 1 3 months postoperatively. Visual refractive outcomes reported. Changes astigmatism...

10.1136/bjophthalmol-2015-307238 article EN British Journal of Ophthalmology 2015-07-23

This study aims to compare the effect of conventional corneal collagen cross-linking (CXL) with accelerated in treatment keratoconus.A comparative interventional was employed.Participants were consecutive cases progressive keratoconus receiving either (3 mW/cm(2) irradiance for 30 min) or CXL (9 10 min).Clinical and topographic parameters compared between two groups. Postoperative stromal demarcation line measured using anterior segment optical coherence tomography.Clinical such as corrected...

10.1111/ceo.12571 article EN Clinical and Experimental Ophthalmology 2015-07-03

Purpose. To study the risk factors, microbial profile, antibiotic susceptibility pattern, and outcome for keratitis over past 10 years in a tertiary center Hong Kong. Methods. All cases with corneal scraping performed Queen Mary Hospital, Kong from January 2004 to December 2013 were included. Clinical was defined as poor if final visual acuity (VA) abnormal or worse than presenting VA, major complication occurred, therapeutic keratoplasty required. Results. 347 scrapes 10-year period growing...

10.1155/2015/769436 article EN cc-by Journal of Ophthalmology 2015-01-01

Purpose: To investigate the prevalence of ocular manifestations and visual outcomes in patients with herpes zoster ophthalmicus (HZO). Methods: Consecutive cases diagnosed HZO who attended 2 hospitals between July 1, 2011, June 30, 2015, were retrospectively reviewed. Patient demographics, clinical presentations, management The logistic regression model was used to estimate odds ratio loss manifestations. Results: A total 259 included. Of these, 110 (42.5%) <60 years old 149 (57.5%) ≥60...

10.1097/ico.0000000000001046 article EN Cornea 2016-10-12

Preoperative anaemia is a strong predictor of blood transfusion requirements and must be assessed for appropriate optimization before elective surgery. Iron therapy transfusion-sparing approach effective increasing haemoglobin concentrations. However, its role in cardiac surgery the optimal route administration remain unknown. This single-centre, non-blinded, randomized, controlled trial compared effectiveness intravenous ferric carboxymaltose with oral iron anaemic patients undergoing Fifty...

10.1093/icvts/ivy226 article EN cc-by Interactive Cardiovascular and Thoracic Surgery 2018-06-24

Abstract Purpose To compare the changes in higher order aberrations (HOA’s) for photopic and mesopic pupil diameters children undergoing orthokeratology treatment (OK) or combined 0.01% atropine with (AOK), their association axial elongation. Methods Children aged 6 to <11 years 1.00–4.00 D of myopia were randomly assigned each group. Photopic quantified using automated pupillometry HOA’s measured a Hartmann‐Shack aberrometer Badal system control accommodation. rescaled fitted th Zernike...

10.1111/opo.12730 article EN Ophthalmic and Physiological Optics 2020-09-05

<h3>Background/aims</h3> This was a cross-sectional survey to find the prevalence of visual impairment and eye diseases among adults with Down syndrome (DS) in Hong Kong. <h3>Methods</h3> 91 DS patients over age 30 were recruited through Kong Syndrome Association. Each patient provided complete ophthalmological assessment including best corrected acuity, refraction, slit lamp fundus examination. <h3>Results</h3> In our sample, 56.6% had normal vision mild impairment, 33.7% 7.2% moderate...

10.1136/bjophthalmol-2012-302327 article EN British Journal of Ophthalmology 2013-02-01

To compare the stromal demarcation line depth at corneal center and its periphery in conventional versus accelerated collagen cross-linking (CXL).Patients with keratoconus who received either 30-minute CXL 3.0 mW/cm² irradiation intensity (group 1) or 10-minute 9.0 2) were included. The 3-mm measured first postoperative month using anterior segment optical coherence tomography compared.Thirty-three patients included (18 group 1, 15 this study. mean was 295 ± 62 μm 1 203 45 2 (P < 0.001)....

10.1097/ico.0000000000000626 article EN Cornea 2015-09-17

To compare the astigmatic correction in high myopic astigmatism between small-incision lenticule extraction and laser situ keratomileusis (LASIK) using vector analysis.Hong Kong Laser Eye Center, Hong Kong.Retrospective case series.Patients who had of 3.0 diopters (D) or more either femtosecond laser-assisted LASIK were included. Only left eye was included for analysis. Visual refractive results presented compared groups.The study comprised 105 patients (40 eyes group 65 group.) The mean...

10.1016/j.jcrs.2018.04.038 article EN Journal of Cataract & Refractive Surgery 2018-06-13

This study aimed to evaluate the efficacy of 18-month 0.01% atropine in 61 myopic children (aged 7-10) and relationship with central retinal response (by multifocal electroretinogram [mfERG]) a double-masked randomized placebo-controlled clinical trial. Global-flash mfERG was measured at baseline, while cycloplegic spherical equivalent refraction (SER) axial length (AL) were baseline 6-month intervals. Annualized change SER AL compared between control groups, relationships evaluated. Changes...

10.1038/s41598-022-15686-6 article EN cc-by Scientific Reports 2022-07-08

Background. To compare the early outcome of combined SMILE and collagen crosslinking (SMILE Xtra) with SMILE. Method. Prospective, comparative interventional study 21 eyes receiving Xtra using a low energy protocol 32 control only. The outcomes were compared at 1, 3, 6 months postoperatively. Results. Both groups had myopia spherical equivalent refraction (SEQ) > 4.00 D. group thinner preoperative central corneal thickness residual stromal bed (p < 0.021). At months, no lost more than 1 line...

10.1155/2016/2672980 article EN cc-by Journal of Ophthalmology 2016-01-01

Purpose To investigate the prevalence, associations, and causes of visual impairment blindness in adult population Hong Kong.Methods This cross-sectional population-based study included 2018 (870, 43% male) randomly selected adults with a mean age 52 ± 16 years (range 18–90 years) Kong. Each participant underwent comprehensive ophthalmic examinations. Presenting acuity (PVA) best-corrected (BCVA) each eye was recorded. Prevalence calculated using both World Health Organization (WHO) United...

10.1080/09286586.2020.1755444 article EN Ophthalmic Epidemiology 2020-04-20

We aim to investigate the effect of sustained hyperglycemia on corneal epithelial wound healing, ocular surface and systemic immune response, microbiome indices in diabetic mice compared controls after alkaline chemical injury eye.Corneal was induced right eye Ins2Akita (Akita) wild-type mice. The groups were observed at baseline subsequently days 0, 3, 7 injury. Corneal re-epithelialization under slit lamp with fluorescein staining using a cobalt blue light filter. Enucleated cornea...

10.3389/fimmu.2023.1063069 article EN cc-by Frontiers in Immunology 2023-01-31
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