A5007576836- Oral microbiology and periodontitis research
- Cancer Treatment and Pharmacology
- Pain Mechanisms and Treatments
- Plant-based Medicinal Research
- Neuropeptides and Animal Physiology
- Inflammatory mediators and NSAID effects
- Bone Metabolism and Diseases
- Multiple Myeloma Research and Treatments
- Bone health and treatments
- Oral and gingival health research
- Acupuncture Treatment Research Studies
- Cancer-related Molecular Pathways
- Endodontics and Root Canal Treatments
- Stress Responses and Cortisol
- Dental Implant Techniques and Outcomes
- Botulinum Toxin and Related Neurological Disorders
- Cancer, Stress, Anesthesia, and Immune Response
- Chemotherapy-related skin toxicity
- Oral Health Pathology and Treatment
- Biological Activity of Diterpenoids and Biflavonoids
- Wound Healing and Treatments
- HIV/AIDS oral health manifestations
- Plant-derived Lignans Synthesis and Bioactivity
- Pressure Ulcer Prevention and Management
- Oral health in cancer treatment
Universidade Federal do Ceará
2014-2023
Unichristus
2020-2023
Universidade Federal de São Paulo
2016
This pilot study evaluated the clinical efficacy of a mouthwash containing 1% Matricaria chamomilla L. (MTC) extract in reducing gingival inflammation and plaque formation patients undergoing orthodontic treatment with fixed appliances. randomized, double-blind, placebo-controlled enrolled total 30 males females (age, 10-40 years) appliances minimum 20 natural teeth. The participants were allocated to three groups (n = 10 each) asked rinse 15 mL placebo, 0.12% chlorhexidine (CHX), or MTC...
Atorvastatin (ATV) has shown pleiotropic effects on bone tissue, and osteoporosis can aggravate periodontitis. Thus, the of ATV experimental periodontitis (EP) in rats subjected to glucocorticoid-induced (GIOP) was assessed.Male Wistar were divided into following groups: 1) naive; 2) EP; 3) GIOP + 4) ATV. Groups EP received 7 mg/kg dexamethasone intramuscularly once per week for 5 weeks, others saline (SAL). EP, submitted by ligature around maxillary left second molars 11 days. Group 27...
Background: It appears there are no studies evaluating the influence of bisphosphonate tiludronic acid (TIL) on periodontitis. The purpose this study is to evaluate via microtomographic, histopathologic, histometric, and immunohistochemical analyses effects local administration TIL ligature‐induced periodontitis in rats. Methods: Forty‐eight rats were divided into six groups: C (control), EP (experimental periodontitis), EP‐Saline, EP‐TIL0.1, EP‐TIL0.3, EP‐TIL1. In EP, a ligature was placed...
Background: Acupuncture has shown the capability of modulating immuno‐inflammatory response host. This study aims to evaluate effects electroacupuncture (EA) on ligature‐induced periodontitis in rats. Methods: Thirty‐two animals were divided into four groups: 1) control; 2) experimental (EP); 3) sham‐treated (EP/EA‐sham); and 4) treated with EA (EP/EA). For EP groups, a ligature was placed around right mandibular first molars at day 1. Sessions or EA‐sham assigned every other day. treatment,...
The association between TP53 gene polymorphisms and breast cancer (BC) in Brazilian women is a controversial topic.In this cross-sectional study, we evaluated the clinical pathological variables three (TP53*11, TP53*72, TP53*248) BC patients controls.Genomic DNA was extracted from blood cells of 393 participants; cancer-free control subjects were 26-72 years old (41 ± 11.03) 28-80 (51 10.70).We used standard polymerase chain reaction-restriction fragment length polymorphism confirmed results...
Tiludronic acid (TIL) presents antiresorptive and anti-inflammatory properties has not been evaluated in the periodontitis-diabetes mellitus (DM) association to date, best knowledge of authors. This study evaluates effects local administration TIL on experimental periodontitis (EP) rats with streptozotocin-induced DM.Thirty-two animals (Rattus norvegicus albinus, Wistar) were divided into groups DM/C (Control), DM/EP, DM/EP/TIL1, DM/EP/TIL3. In EP groups, a ligature was placed around...
Abstract This study aimed to evaluate the effects of inhibitors fractalkine pathway in hyperalgesia inflammatory and neuropathic orofacial pain male rats morphological changes microglia satellite glial cells (SGCs). Rats were submitted zymosan‐induced arthritis temporomandibular joint or infraorbital nerve constriction, treated intrathecally with a P 2 X 7 antagonist, cathepsin S inhibitor p‐38 mitogen‐activated protein kinase (MAPK) inhibitor. Mechanical was evaluated 4 6 h following...
Sensory neuropathy is a dose-limiting side effect of oxaliplatin-based cancer treatment. This study investigated the antinociceptive amifostine and its potential neuroprotective mechanisms on oxaliplatin-related peripheral sensory in mice. Oxaliplatin (1 mg/kg) was injected intravenously Swiss albino male mice twice week (total nine injections), while (1, 5, 25, 50, 100 administered subcutaneously 30 min before oxaliplatin. Mechanical thermal nociceptive tests were performed once for 49...
Objective There is wide discrepancy on how to perform clinical assessment of oxaliplatin-induced peripheral neuropathy. In this scenario, the Electronic von Frey (EVF), which evaluates pain objectively based upon mechanical thresholds (MPTs), may be a valuable tool. The present study aims quantify hyperalgesia in hands and feet patients treated with oxaliplatin propose novel method classify degree neurotoxicity using EVF-derived measures as cut-off points. Methods This prospective cohort...
Introdução: Malformações congênitas são anomalias estruturais presentes desde o nascimento que podem surgir de fatores genéticos, ambientais ou interações entre ambos. Muitas dessas malformações ser explicadas através da embriologia clínica fornece uma visão crítica sobre a formação e desenvolvimento dos órgãos sistemas, permitindo melhor compreensão das origens anomalias. Esse artigo tem como objetivo elencar as principais se relacionam com alterações embriológicas, explicando suas...
Introduction: Inhalational anesthetics are often the first choice in pediatric anesthesia. However, most recent literature demonstrates possible advantages of total intravenous anesthesia (TIVA). The goal this study was to compare postoperative quality children submitted tonsillectomy under TIVA versus sevoflurane Materials and Methods: Prospective observational case-control (Sevoflurane vs TIVA) including (adeno) considering intra parameters. Data collected from clinical records, anesthetic...