Javier Arbizu

ORCID: 0000-0002-8370-5510
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About
Contact & Profiles
Research Areas
  • Medical Imaging Techniques and Applications
  • Dementia and Cognitive Impairment Research
  • Glioma Diagnosis and Treatment
  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's disease research and treatments
  • Neurological disorders and treatments
  • Advanced MRI Techniques and Applications
  • Autoimmune Neurological Disorders and Treatments
  • Functional Brain Connectivity Studies
  • Health Systems, Economic Evaluations, Quality of Life
  • Radiomics and Machine Learning in Medical Imaging
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Radiopharmaceutical Chemistry and Applications
  • Prion Diseases and Protein Misfolding
  • Alcoholism and Thiamine Deficiency
  • Brain Metastases and Treatment
  • Radiation Dose and Imaging
  • Medical Imaging and Pathology Studies
  • Diet and metabolism studies
  • Neurological and metabolic disorders
  • Neuroendocrine Tumor Research Advances
  • Peripheral Neuropathies and Disorders
  • Neuroblastoma Research and Treatments
  • Neuroscience and Neuropharmacology Research
  • Neurological diseases and metabolism

Clinica Universidad de Navarra
2016-2025

Universidad de Navarra
2010-2025

John Wiley & Sons (United States)
2024

University Hospital of Geneva
2021

Stockholm Health Care Services
2021

Karolinska Institutet
2021

Ospedale Policlinico San Martino
2021

Navarre Institute of Health Research
2020

University of Zurich
2016

Ludwig-Maximilians-Universität München
2016

These joint practice guidelines, or procedure standards, were developed collaboratively by the European Association of Nuclear Medicine (EANM), Society and Molecular Imaging (SNMMI), Neurooncology (EANO), working group for Response Assessment in with PET (PET-RANO). Brain imaging is being increasingly used to supplement MRI clinical management glioma. The aim these standards/guidelines assist nuclear medicine practitioners recommending, performing, interpreting reporting results brain...

10.1007/s00259-018-4207-9 article EN cc-by European Journal of Nuclear Medicine and Molecular Imaging 2018-12-05

To the authors' knowledge, liver damage after radioembolization with yttrium90-labeled microspheres has never been studied specifically.Using a complete set of data recorded prospectively among all patients without previous chronic disease treated by at institution from September 2003 to July 2006, patterns were identified and possible risk factors analyzed.In all, 20% developed distinct clinical picture that appeared 4 8 weeks treatment was characterized jaundice ascites. Veno-occlusive...

10.1002/cncr.23339 article EN Cancer 2008-02-07

Abstract Purpose This joint practice guideline or procedure standard was developed collaboratively by the European Association of Nuclear Medicine (EANM) and Society Molecular Imaging (SNMMI). The goal this is to assist nuclear medicine practitioners in recommending, performing, interpreting, reporting results dopaminergic imaging parkinsonian syndromes. Methods Currently investigations can assess both presynaptic postsynaptic function synapses. To date EANM SNMMI have published procedural...

10.1007/s00259-020-04817-8 article EN cc-by European Journal of Nuclear Medicine and Molecular Imaging 2020-05-09

Recommendations for using fluorodeoxyglucose positron emission tomography (FDG-PET) to support the diagnosis of dementing neurodegenerative disorders are sparse and poorly structured.Twenty-one questions on diagnostic issues semi-automated analysis assist visual reading were defined. Literature was reviewed assess study design, risk bias, inconsistency, imprecision, indirectness effect size. Critical outcomes sensitivity, specificity, accuracy, positive/negative predictive value, area under...

10.1111/ene.13728 article EN European Journal of Neurology 2018-06-22

The Alzheimer's Association and the Society of Nuclear Medicine Molecular Imaging convened a multidisciplinary workgroup to update appropriate use criteria (AUC) for amyloid positron emission tomography (PET) develop AUC tau PET. <b>Methods:</b> identified key research questions that guided systematic literature review on clinical amyloid/tau Building this review, developed 17 scenarios in which or PET may be considered. A modified Delphi approach was used rate each scenario by consensus as...

10.2967/jnumed.124.268756 article EN cc-by Journal of Nuclear Medicine 2025-01-08

Flicker stimuli of variable frequency (2-90 Hz) elicit a steady-state visual-evoked response (SSVER) in the electroencephalogram (EEG) with same as stimulus. In humans, amplitude this peaks at approximately 15 Hz, decreasing higher stimulation frequencies. It was not known whether peak corresponds to increased synaptic activity visual cortex or other mechanisms [for instance, temporal coherence (phase summation) evoked responses]. We studied SSVER 16 normal volunteers by means 14 different...

10.1523/jneurosci.23-37-11621.2003 article EN Journal of Neuroscience 2003-12-17

We used functional brain imaging with positron emission tomography (PET)-H<sub>2</sub><sup>15</sup>O to study a remarkable neurophysiological finding in the normal brain. Auditory stimulation at various frequencies gamma range elicits steady-state scalp electroencephalographic (EEG) response that peaks amplitude 40 Hz, smaller amplitudes lower and higher frequencies. confirmed this 28 healthy subjects, each studied monaural trains of stimuli 12 different rates (12, 20, 30, 32, 35, 37.5, 40,...

10.1523/jneurosci.22-23-10501.2002 article EN Journal of Neuroscience 2002-12-01

The pathophysiological process underlying cognitive decline in Parkinson's disease is not well understood. Cerebral atrophy and hypometabolism have been described patients with dementia or mild impairment respect to control subjects. However, the exact relationships between are still unclear. To determine extension topographical distribution of different states disease, we examined 46 (19 female, 27 male; 71.7 ± 5.9 years old; 14.6 4.2 evolution; modified Hoehn Yahr mean stage 3.1 0.7)....

10.1093/brain/awu159 article EN Brain 2014-06-20

Abstract Background Peptide receptor radionuclide therapy (PRRT) is one of the most promising therapeutic strategies in neuroendocrine neoplasms (NENs). Nevertheless, its role certain tumor sites remains unclear. This study sought to elucidate efficacy and safety [ 177 Lu]Lu-DOTATATE NENs with different locations evaluate effect origin, bearing mind other prognostic variables. Advanced overexpressing somatostatin receptors (SSTRs) on functional imaging, any grade or location, treated at 24...

10.1007/s00259-023-06166-8 article EN cc-by European Journal of Nuclear Medicine and Molecular Imaging 2023-03-06

Abstract Epilepsy is one of the most frequent neurological conditions with an estimated prevalence more than 50 million people worldwide and annual incidence two million. Although pharmacotherapy anti-seizure medication (ASM) treatment choice, ~30% patients epilepsy do not respond to ASM become drug resistant. Focal form epilepsy. In drug-resistant focal epilepsy, surgery a option depending on localisation seizure focus for relief or freedom consecutive improvement in quality life. Beside...

10.1007/s00259-024-06656-3 article EN cc-by European Journal of Nuclear Medicine and Molecular Imaging 2024-02-23

Background and Purpose— The boundary between vascular dementia Alzheimer disease (AD) continues to be unclear. Some posit that gradually progressive dementia, as with small vessel disease, is simply plus AD. Because AD presents a characteristic pattern on fluorodeoxyglucose positron emission tomography, we sought determine whether the of resembled more or in nondemented patients severe microvascular brain disease. Methods— Vascular were selected basis confluent white matter lesions both...

10.1161/strokeaha.110.591552 article EN Stroke 2010-11-05

Early-onset Alzheimer disease (EOAD), which presents in patients younger than 65 years, has frequently been described as having different features from those of late-onset (LOAD). This review analyses the most recent studies comparing clinical presentation and neuropsychological, neuropathological, genetic, neuroimaging findings both types order to determine whether EOAD LOAD are entities or distinct forms same entity. We observed consistent differences between LOAD. Fundamentally, onset is...

10.1016/j.nrleng.2015.08.009 article ES cc-by-nc-nd Neurología (English Edition) 2017-01-09

The aim of this study was to retrospectively evaluate the patient effective dose (ED) for different PET/CT procedures performed with a variety PET radiopharmaceutical compounds. studies 210 patients were reviewed including Torso (n = 123), Whole body (WB) 36), Head and Neck Tumor (HNT) 10), Brain 41) protocols 18FDG 170), 11C-CHOL 18FDOPA 11C-MET 18F-florbetapir 10). ED calculated using conversion factors applied radiotracer activity CT dose-length product. Total (mean ± SD) Torso-11C-CHOL,...

10.1186/s13550-017-0272-5 article EN cc-by EJNMMI Research 2017-04-24
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