A5030338546- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Inhalation and Respiratory Drug Delivery
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Allergic Rhinitis and Sensitization
- Delphi Technique in Research
- Respiratory viral infections research
- Nursing Diagnosis and Documentation
- Pneumonia and Respiratory Infections
- Pharmaceutical studies and practices
- Tracheal and airway disorders
- Medical Imaging Techniques and Applications
- Scoliosis diagnosis and treatment
- School Health and Nursing Education
- Global Healthcare and Medical Tourism
- Congenital Diaphragmatic Hernia Studies
- Technology Use by Older Adults
- Congenital limb and hand anomalies
- Nail Diseases and Treatments
- Hemostasis and retained surgical items
- Diagnosis and treatment of tuberculosis
- Health, psychology, and well-being
- Lung Cancer Research Studies
- Restraint-Related Deaths
Singapore General Hospital
2022-2025
Newcastle University
2022
University of Southampton
2020
Cipla (India)
2013-2016
Indian Institute of Management Calcutta
2013
University of Delhi
2007-2008
Respiratory syncytial virus (RSV) is a significant global health concern and major cause of hospitalization, particularly among infants older adults. The clinical impact RSV well characterized in infants; however, many countries, the burden risk populations are overlooked. In Latin America, there limited data on epidemiology disease management Therefore, this region needs to be addressed. Here, current insights infections including those with underlying conditions, discussed. We also outline...
Mounier-Kuhn syndrome is a rare congenital abnormality characterized by atrophy or absence of elastic fibers and thinning smooth muscle layer in the trachea main bronchi. These airways are thus flaccid markedly dilated on inspiration collapsed expiration. First- to fourth-order bronchi affected. There an increase dead space, tidal volume diminished clearing secretions. The usual presentation recurrent respiratory tract infections with broad spectrum functional impairment ranging from minimal...
BackgroundThe 2021 Global Initiative for Asthma (GINA) report recommends 2 treatment tracks depending on choice of reliever therapy: either inhaled corticosteroid (ICS)/formoterol, or short-acting β2-agonist (SABA) with ICS to be used whenever a SABA is taken.ObjectiveThe Patients' and Physicians' Perspectives the Burden Management (APPaRENT) study aimed understand current real-world approaches their alignment GINA recommendations.MethodsPatients physicians were recruited online survey from...
Despite the proven benefits of inhaled corticosteroid (ICS)-containing triple therapy for chronic obstructive pulmonary disease (COPD), clinicians limit patient exposure to ICS due risk pneumonia. However, there are multiple factors associated with pneumonia in patients COPD. This post hoc analysis IMPACT trial data aims set risks into a context specific patient-related that contribute The 52-week, double-blind randomized symptomatic COPD and ≥1 exacerbation prior year 2:2:1 once-daily...
Asthma treatment guidelines classify inhaled corticosteroid (ICS) regimens as low, medium, or high dose. However, efficacy and safety are not independently assessed accordingly. Moreover, differences in ICS duration of action considered when a dose regimen is selected. We investigated the implications these limitations for available molecules. Published pharmacodynamic pharmacokinetic parameters were used, alongside physiological pharmacological principles, to estimate Extent glucocorticoid...
Clinical studies demonstrate an accelerated decline in lung function patients with moderate chronic obstructive pulmonary disease (COPD) (Global Initiative for Chronic Obstructive Lung Disease [GOLD] grade 2) versus severe and very COPD (GOLD grades 3 4). This predictive modelling study assessed the impact of initiating pharmacotherapy earlier later on long-term progression COPD. The approach used data forced expiratory volume 1 s (FEV1) extracted from published to develop a longitudinal...
Asthma management is strongly dependent on physician and patient beliefs perceptions about the disease its long-term treatment. The APPaRENT 3 study was conducted to explore factors influencing treatment choice understand patients' physicians' attitudes perspectives use of controller inhalers in regular versus flexible dosing for asthma management. This cross-sectional survey patients with treating physicians seven countries: Indonesia, Malaysia, Philippines, Thailand, Vietnam (patient...
Background: Challenges exist in the diagnosis, management and follow-up of patients with chronic obstructive pulmonary disease (COPD) India. Lack awareness disease, its symptoms implications may significantly contribute preventing individuals from seeking advice their primary care physicians or eliminating risk factors. This cross-sectional survey aimed to explore attitudes, beliefs, knowledge doctors (general practitioners [GPs], pulmonologists) related COPD recognition, treatment Methods:...
Objective: To describe patient characteristics, treatment patterns and healthcare utilization (HCU) of non-active users maintenance asthma medications in the United Kingdom.Methods: Retrospective, cohort analysis patients with asthma, aged ≥ 6 years who were therapy (no prescription for inhaled corticosteroids (ICS), combined ICS/long-acting beta agonists (ICS/LABA) or 'other' bronchodilatory therapies last 12 months) identified Clinical Practice Research Datalink (2012–2015) followed-up 2...
Role of triple therapy in chronic obstructive pulmonary disease (COPD) management is supported by growing evidence, but consensus lacking on various aspects. We conducted a Delphi survey respiratory experts the effects exacerbation reduction, early optimization, pneumonia risk, and mortality benefits COPD management.The study comprised 2-round online surveys participant meeting with 21 from 10 countries. The 31-statement questionnaire was prepared using Decipher software after literature...
Asthma and allergic rhinitis (AR) frequently coexist, having both asthma AR is associated with uncontrolled a heavier disease burden. The Asia-Pacific Survey of Physicians on Allergic Rhinitis (ASPAIR) aimed to assess physicians' perceptions their management practices for patients coexistent disease.A total 1,204 general physicians pediatricians from six countries in Asia, who routinely treat patients, were interviewed in-person. questioned about attitudes beliefs asthma-AR, how they...
The COVID-19 pandemic has brought a renewed focus on appropriate management of chronic respiratory conditions with heightened awareness symptoms and the requirement for differential diagnosis between an asthma attack infection. Despite early concerns in pandemic, most studies suggest that well-managed is not risk factor more severe COVID-related outcomes, may even have protective effect. Advice treatment attacks remained unchanged. This article describes some challenges faced primary care...
Clinical remission is a relatively new concept in asthma but recent research initiatives suggest it could be an ambitious and achievable therapeutic target for patients with asthma.
Objective: To determine the effectiveness of influenza vaccination on acute respiratory illness (ARI) and exacerbation chronic obstructive pulmonary disease (AECOPD) during a 2-year study conducted prior to after in patients with (COPD). Materials methods: Eighty-seven male COPD were stratified basis their forced expiratory volume 1 s (FEV1) as having mild, moderate severe COPD. These evaluated for total duration 2 years; year period following vaccination. The vaccine (split virion,...
This study compared the bronchoprotective and benefit/risk profiles of various inhaled corticosteroid (ICS) dosing regimens in mild asthma. A pharmacokinetic/pharmacodynamic model was developed validated describing relationship between ICS dose time-course for airway bronchoprotection, [provocative concentration adenosine monophosphate (AMP) causing ≥ 20% decline forced expiratory volume 1 s (FEV1) (AMP PC20)], fluticasone furoate (FF), propionate (FP) budesonide (BUD). For regular...