Melanie Penner

ORCID: 0000-0002-8376-9768
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About
Contact & Profiles
Research Areas
  • Autism Spectrum Disorder Research
  • Family and Disability Support Research
  • Child Nutrition and Feeding Issues
  • Child and Adolescent Health
  • Adolescent and Pediatric Healthcare
  • Attention Deficit Hyperactivity Disorder
  • Infant Development and Preterm Care
  • Child Development and Digital Technology
  • Health Policy Implementation Science
  • Child and Adolescent Psychosocial and Emotional Development
  • Childhood Cancer Survivors' Quality of Life
  • Health Systems, Economic Evaluations, Quality of Life
  • Behavioral and Psychological Studies
  • Genetics and Neurodevelopmental Disorders
  • Cerebral Palsy and Movement Disorders
  • Pharmaceutical studies and practices
  • Antibiotic Use and Resistance
  • Emergency and Acute Care Studies
  • Assistive Technology in Communication and Mobility
  • Family and Patient Care in Intensive Care Units
  • Urinary Tract Infections Management
  • Patient Satisfaction in Healthcare
  • COVID-19 and Mental Health
  • Urinary Bladder and Prostate Research
  • Schizophrenia research and treatment

Holland Bloorview Kids Rehabilitation Hospital
2016-2025

University of Toronto
2015-2025

Canadian Paediatric Society
2023

Autism Research Institute
2022

Owl Research Institute
2017

Institute for Clinical Evaluative Sciences
2015

Hospital for Sick Children
2015

SickKids Foundation
2015

OBJECTIVES: Pain in children with cerebral palsy (CP) is underrecognized, undertreated, and negatively affects quality of life. Communication challenges multiple pain etiologies complicate diagnosis treatment. The primary objectives this study were to determine the impact on activities identify common physician-identified causes youth ages 3 19 years across all levels severity CP. METHODS: design was cross-sectional, whereby children/youth aged their families consecutively recruited....

10.1542/peds.2013-0224 article EN PEDIATRICS 2013-07-16

Introduction: Burnout, inertia, meltdown, and shutdown (BIMS) have been identified as important parts of some autistic people’s lives. This study builds on our previous work that offered early academic descriptions these phenomena, based the perspectives adults. Objectives: aimed to explore unique knowledge insights eight children youth extend refine earlier description burnout, i nertia, with additional exploration shutdown. We also how cope phenomena what others around them do make things...

10.3389/fpsyg.2021.741421 article EN cc-by Frontiers in Psychology 2021-11-03

Importance Wait times for autism spectrum disorder (ASD) diagnosis are lengthy because of inadequate supply specialist teams. General pediatricians may be able to diagnose some cases ASD, thereby reducing wait times. Objective To determine the accuracy ASD diagnostic assessments conducted by general compared with a multidisciplinary team (MDT). Design, Setting, and Participants This prospective study was in assessment center Toronto, Ontario, Canada, Ontario pediatrician practices from June...

10.1001/jamanetworkopen.2022.52879 article EN cc-by-nc-nd JAMA Network Open 2023-01-25

Inefficient diagnostic practices for autism spectrum disorder (ASD) may contribute to longer wait times, delaying access intervention. The objectives were describe the of Canadian pediatricians and identify determinants time ASD diagnosis. An online survey was conducted through Paediatric Society's developmental pediatrics, community mental health sections. Participants asked demographic information, whether they diagnosed ASD, elements their assessment. A multiple linear regression total...

10.1186/s13229-018-0201-0 article EN cc-by Molecular Autism 2018-03-06

Objective Early identification of autism spectrum disorder (ASD) is an essential healthcare priority. Girls may be at risk for late diagnosis, although research equivocal regarding how sex and other factors relate to ASD identification. The goals the current investigation were (1) identify child sex, cognitive abilities, demographic age first concern (AOC) diagnosis (AOD), (2) evaluate trends in AOC/AOD over time, (3) consider whether main effects on are moderated by abilities or time.Method...

10.1080/15374416.2020.1823850 article EN Journal of Clinical Child & Adolescent Psychology 2020-11-02

Abstract Background The prescribing of antidepressants and antipsychotics to children has increased worldwide, but little is known about how changes in drug funding policy influence the practice. In 2018, Ontario introduced a universal pharmacare program (OHIP+) for youth, amending it April 2019 cover only those without private insurance. We examined association these with antipsychotic antidepressant medication prescribing. Methods conducted population-based study dispensing ≤ 18 years old...

10.1186/s12887-024-05345-2 article EN cc-by BMC Pediatrics 2025-02-08

<title>Abstract</title> <bold>Background: </bold>In the general population, adaptive functioning typically aligns with cognitive abilities; however, this relationship appears more complex among neurodivergent individuals. Neurodevelopmental conditions (NDCs), including autism, attention-deficit/hyperactivity disorder (ADHD), and obsessive-compulsive (OCD), are associated significant differences between functioning, described as cognitive-adaptive gap. While gap has been examined primarily in...

10.21203/rs.3.rs-5968118/v1 preprint EN cc-by Research Square (Research Square) 2025-02-11

Psychotropic medications are commonly used for neurodivergent children, but their effectiveness varies, making prescribing challenging and potentially exposing individuals to multiple medication trials. We developed artificial intelligence (AI) models predict success stimulants, anti-depressants, anti-psychotics. first demonstrate feasibility using cross-sectional data from three research cohorts, then use a cohort of patients pharmacology clinic choice by class, longitudinally, electronic...

10.1101/2025.03.12.25323683 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2025-03-15

<sec> <title>BACKGROUND</title> Family caregivers of individuals with neurodevelopmental disabilities (NDDs) experience high levels stress, anxiety, and depression, yet few interventions are designed to improve their mental well-being. Additionally, most evidence-based do not actively involve as peer facilitators. </sec> <title>OBJECTIVE</title> To address this gap, we developed an Acceptance Commitment Training (ACT) group intervention co-facilitated by trained clinicians. This study...

10.2196/preprints.75049 preprint EN 2025-03-28

<h3>Importance</h3> Earlier access to intensive behavioral intervention (IBI) is associated with improved outcomes for children severe autism spectrum disorder (ASD); however, there are long waiting times this program. No analyses have been performed modeling the cost-effectiveness of wait time reduction IBI. <h3>Objectives</h3> To model starting age IBI reduced (RWT) (by half) and eliminated (EWT), perform a analysis comparing RWT EWT current (CWT) from government societal perspectives....

10.1001/jamapediatrics.2016.2695 article EN JAMA Pediatrics 2016-11-14

Community general pediatricians (CGPs) are a potential resource to increase capacity for autism spectrum disorder (ASD) diagnostic assessments. The objective of this study was explore factors influencing CGPs' perspectives on and practices providing ASD diagnoses.This qualitative used constructivist modified grounded theory approach. Participants included CGPs who had attended educational events or referred child with suspected tertiary rehabilitation center. Individual in-depth interviews...

10.1097/dbp.0000000000000483 article EN Journal of Developmental & Behavioral Pediatrics 2017-09-20

The COVID-19 pandemic has led to an increase in screen time for children and families. Traditionally, been associated with negative physical mental health outcomes, autism spectrum disorder (ASD) are at increased risk of these outcomes. primary objectives this study were (1) characterize the change during school closures ASD, (2) examine parent perceived impact on quality life their Canadian parents caregivers 19 years age younger eligible participate anonymous, online survey study. This was...

10.3389/fpsyt.2021.702774 article EN cc-by Frontiers in Psychiatry 2021-08-18

Abstract Neurodevelopmental conditions can be associated with decreased health-related quality of life; however, the predictors these outcomes remain largely unknown. We characterized life (HRQoL) in a sample neurodiverse children and youth. used cross-sectional subsample from Province Ontario Disorders Network (POND) consisting those young people POND dataset complete study data (total n = 615; 31% female; age: 11.28 years ± 2.84 years). Using structural equation model, we investigated...

10.1038/s41598-024-56821-9 article EN cc-by Scientific Reports 2024-03-16

The number of young adults (youth) living with childhood-onset disabilities, and requiring transitional support to adult community rehabilitation services, is increasing. We explored facilitators barriers accessing sustaining services during the transition from pediatric care.A qualitative descriptive study was conducted in Ontario, Canada. Data were collected through interviews youth (n = 11) family caregivers 7). data coded analyzed using thematic analysis.Youth face many types transitions...

10.3390/jcm12041693 article EN Journal of Clinical Medicine 2023-02-20

COVID-19 associated public health measures and school closures exacerbated symptoms in some children youth with attention-deficit hyperactivity disorder (ADHD). Less well understood is how the pandemic influenced patterns of prescription stimulant use. We conducted a population-based study dispensing to ≤ 24 years old between January 1, 2013, June 30, 2022. used structural break analyses identify month(s) when changes stimulants occurred. interrupted time series models quantify following...

10.1007/s00787-023-02346-x article EN cc-by European Child & Adolescent Psychiatry 2024-01-05

Abstract Background Population-based research examining geographic variability in psychotropic medication dispensing to children and youth the sociodemographic correlates of such variation is lacking. Variation use could reflect disparities access non-pharmacologic interventions identify potentially concerning patterns. Methods We conducted a population-based study all Ontario residents aged 0 24 years who were dispensed benzodiazepine, stimulant, antipsychotic or antidepressant between...

10.1186/s12889-022-14677-6 article EN cc-by BMC Public Health 2023-01-11

Abstract Background Young adults with childhood-onset disabilities experience challenges accessing age appropriate primary health care services as they transition from pediatric to adult services. They often a negative impact on their associated long-term and social concerns, disease complications increased use of emergency once transitioned This is particularly challenging for youth cerebral palsy (CP) due the complexity medical needs. The aim this study was explore experiences or providing...

10.1515/jtm-2019-0004 article EN cc-by Journal of Transition Medicine 2019-12-10
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