A5061920729- Diabetes and associated disorders
- Pancreatic function and diabetes
- Diabetes Management and Research
- Olfactory and Sensory Function Studies
- HIV Research and Treatment
- Neurofibromatosis and Schwannoma Cases
- HIV/AIDS Research and Interventions
- Trauma Management and Diagnosis
- Veterinary Oncology Research
- Ocular Oncology and Treatments
- HIV/AIDS drug development and treatment
- Congenital Diaphragmatic Hernia Studies
- Primate Behavior and Ecology
- Animal Vocal Communication and Behavior
- Tracheal and airway disorders
The University of Texas MD Anderson Cancer Center
2022-2023
Tulane University
2021-2022
Pancreatic islet transplantation efficacy for type 1 diabetes (T1D) management is limited by hypoxia-related graft attrition and need systemic immunosuppression. To overcome these challenges, we developed the Neovascularized Implantable Cell Homing Encapsulation (NICHE) device, which integrates direct vascularization facile mass transfer localized immunosuppressant delivery rejection prophylaxis. Here, investigated NICHE allogeneic long-term reversal in an immunocompetent, male rat model. We...
Several implantable long-acting (LA) delivery systems have been developed for sustained subcutaneous administration of tenofovir alafenamide (TAF), a potent and effective nucleotide reverse transcriptase inhibitor used HIV pre-exposure prophylaxis (PrEP). LA platforms aim to address the lack adherence oral regimens, which has impaired PrEP efficacy. Despite extensive investigations in this field, tissue response TAF remains be elucidated as contrasting preclinical results reported...
Abstract Pancreatic islet transplantation efficacy for type 1 diabetes (T1D) management is limited by hypoxia-related graft attrition and need systemic immunosuppression. To overcome these challenges, we developed the Neovascularized Implantable Cell Homing Encapsulation (NICHE) device, which integrates direct vascularization facile mass transfer localized immunosuppressant delivery rejection prophylaxis. Here, investigated NICHE allogeneic long-term reversal in an immunocompetent rat model....
Social housing is one of the best forms environmental enhancement for nonhuman primates, and current research into pair compatibility introduction techniques focuses on improving safety outcome. The gradual steps method (GS), which widely used introducing indoor-housed macaques, involves an initial phase limited physical contact to allow animals acclimate another prior full contact. A safer, more efficacious needed. administration diazepam, a sedating anxiolytic medication, known increase...
Abstract Tracheal disruption is a previously unreported complication of nonhuman primate social trauma. Two cases were identified in rhesus macaques with subcutaneous emphysema. These resolved medical management and demonstrate that the combined use radiography tracheoscopy allows rapid assessment diagnosis tracheal trauma primates.
Abstract Tumors of the skin and subcutaneous tissues are uncommon in marmosets. In this report, we describe gross, histopathology, immunohistochemical findings a nerve sheath tumor that arose left forearm an adult female marmoset ( Callthrix jacchus ).