A5059818562- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Blood transfusion and management
- Platelet Disorders and Treatments
- RNA modifications and cancer
- Hemostasis and retained surgical items
Zhongda Hospital Southeast University
2022-2023
Nanjing University
2022
N6 -methyladenosine (m6A) is one of the most abundant internal RNA modifications. We investigated role m6A-modified circRERE in osteoarthritis (OA) and its mechanism.CircRERE IRF2BPL were screened by microarrays. The m6A-modification was examined methylated precipitation morpholino oligo (MOs) treatment. axis circRERE/miR-195-5p/IRF2BPL/β-catenin determined using flow cytometry, western blotting immunofluorescence human chondrocytes (HCs) corroborated a mouse model destabilization medial...
Abstract Trial design: This study prospectively analyzes the effect of EPO combined with Iron sucrose on postoperative anemia prevention and prognosis patients TKA. Methods: Participants in this will be randomly assigned to a treatment group or control group. Patients receive for ten days iron injection three preoperative. The general data, hematological indexes, transfusion rate, total blood loss, knee joint function score analyzed. Results: 92 met inclusion criteria, including 46 There...