- Tendon Structure and Treatment
- Advanced Sensor and Energy Harvesting Materials
- Conducting polymers and applications
- Catalysis for Biomass Conversion
- Osteoarthritis Treatment and Mechanisms
- Tactile and Sensory Interactions
- Shoulder Injury and Treatment
- Periodontal Regeneration and Treatments
- Biofuel production and bioconversion
- Knee injuries and reconstruction techniques
- Catalysis and Hydrodesulfurization Studies
- Laser Applications in Dentistry and Medicine
- Manufacturing Process and Optimization
- Cytokine Signaling Pathways and Interactions
- Electrospun Nanofibers in Biomedical Applications
- Industrial Vision Systems and Defect Detection
- Supercapacitor Materials and Fabrication
- Cancer-related molecular mechanisms research
- Spine and Intervertebral Disc Pathology
- Bone Tissue Engineering Materials
- Management of metastatic bone disease
- Spinal Fractures and Fixation Techniques
- Catalysts for Methane Reforming
- Muscle Physiology and Disorders
- Lymphoma Diagnosis and Treatment
Zhengzhou University
2023-2025
Zhongda Hospital Southeast University
2016-2024
Southeast University
2021-2024
Fujian Medical University
2021-2024
First Affiliated Hospital of Fujian Medical University
2021-2024
Planetary Science Institute
2024
Rutgers, The State University of New Jersey
2024
University of Southern California
2020-2022
National University of Kaohsiung
2011-2021
Nanjing Medical University
2020-2021
Electronic skin (e-skin), mimicking the physical–chemical and sensory properties of human skin, is promising to be applied as robotic skins skin-attachable wearables with multisensory functionalities. To date, most e-skins are dedicated function development mimic in one or several aspects, yet advanced e-skin covering all hyper-attributes (including both properties) seldom reported. Herein, a water-modulated biomimetic hyper-attribute-gel (Hygel) reversible gel–solid transition proposed,...
Abstract Background and Aims The study objective was to compare the effectiveness of microwave ablation (MWA) laparoscopic liver resection (LLR) on solitary 3–5‐cm HCC over time. Approach Results From 2008 2019, 1289 patients from 12 hospitals were enrolled in this retrospective study. Diagnosis all lesions based histopathology. Propensity score matching used balance baseline variables between two groups 2008–2019 ( n = 335 each group) 2014–2019 257 cohorts, respectively. For cohort...
N6 -methyladenosine (m6A) is one of the most abundant internal RNA modifications. We investigated role m6A-modified circRERE in osteoarthritis (OA) and its mechanism.CircRERE IRF2BPL were screened by microarrays. The m6A-modification was examined methylated precipitation morpholino oligo (MOs) treatment. axis circRERE/miR-195-5p/IRF2BPL/β-catenin determined using flow cytometry, western blotting immunofluorescence human chondrocytes (HCs) corroborated a mouse model destabilization medial...
Abstract Background Although mesenchymal stem cells (MSCs) have been effective in tendinopathy, the mechanisms by which MSCs promote tendon healing not fully elucidated. In this study, we tested hypothesis that transfer mitochondria to injured tenocytes vitro and vivo protect against Achilles tendinopathy (AT). Methods Bone marrow H 2 O -injured were co-cultured, mitochondrial was visualized MitoTracker dye staining. Mitochondrial function, including membrane potential, oxygen consumption...
// Yu-Cheng Lin 1,* , Ying-Juan Li 2,* Yun-Feng Rui 1,3,4 Guang-Chun Dai 1 Liu Shi 1,5,6 Hong-Liang Xu 3 Ming Ni 7 Song Zhao Hui Chen Wang Gang 5,6 and Gao-Jun Teng 8 Department of Orthopaedics, Zhongda Hospital, School Medicine, Southeast University, Nanjing, Jiangsu, China 2 Geriatrics, Xishan People's Wuxi, 4 Orthopedic Regenerative Medicine Group, 5 Orthopaedics Traumatology, Faculty The Chinese University Hong Kong, SAR, 6 Program Stem Cell Regeneration, Biomedical Science, Ka Shing...
In order to accelerate the tendon-bone healing processes and achieve efficient osteointegration between tendon graft bone tunnel, we aim design bioactive electrospun nanofiber membranes combined with stem/progenitor cells (TSPCs) promote osteogenic regeneration of interface.In this study, polycaprolactone (PCL), PCL/collagen I (COL-1) hybrid membranes, poly(dopamine) (PDA)-coated PCL PDA-coated PCL/COL-1 were successfully fabricated by electrospinning. The biochemical characteristics...
Wearable sensors with water resistance and mechanical durability are of great value in dealing long‐term movement remote control harsh environments. However, achieving high sensitivity stability real‐time a watery environment is still challenge. Herein, the waterproof wearable good robustness composed laser‐induced graphene situ‐coated protective silicone layers reported. By being integrated high‐capacitance ion‐gel dielectrics, conformal can detect multiple stimuli, including strain,...
Self‐powered flexible tactile sensors based on triboelectric nanogenerators (TENGs) can be of use in the development robotic intellisense and interaction. Such typically triboelectronegative material as top layer, requiring contacting separating with specific interface to operate, may result suboptimal performance under practical conditions. Herein, a self‐powered interface‐independent sensor array that is bilayer single‐electrode TENGs reported. By integrating both triboelectropositive...
Abstract Background Due to the unclear pathogenesis of osteoarthritis (OA), effective treatment for this ailment is presently unavailable. Accumulating evidence points chondrocyte senescence as a key driver in OA development. This study aims identify OA-specific microRNAs (miRNAs) targeting alleviate progression. Methods We screened and identified miRNAs differentially expressed normal cartilage, then confirmed impact miR-653-5p on functions phenotypes through vitro experiments with...
Scar tissue formation at the tendon-bone interface caused by excessive inflammation leads to insufficient healing strength, while phagocytic clearance of dying cells (efferocytosis) has profound consequences on macrophage polarisation and inflammatory response. Modulating microenvironment may have satisfactory curative effects in patients with anterior cruciate ligament reconstruction (ACLR). Bone marrow-derived macrophages (BMDMs) polymorphonuclear leukocytes (PMNs) were harvested from bone...
Reliable, wide range, and highly sensitive joint movement monitoring is essential for training activities, human behavior analysis, human-machine interfaces. Yet, most current motion sensors work on the nano/microcracks induced by tensile deformation convex surface of joints during movements, which cannot satisfy requirements ultrawide detectable angle high sensitivity, conformability, consistence under cyclic movements. In nature, scorpions sense small vibrations allowing compression strain...
Abstract Growth of long bones and vertebrae is maintained postnatally by a long-lasting pool progenitor cells. Little known about the molecular mechanisms that regulate output maintenance cells give rise to mature cartilage. Here we demonstrate postnatal chondrocyte-specific deletion transcription factor Stat3 results in severely reduced proliferation coupled with increased hypertrophy, growth plate fusion, stunting signs progressive dysfunction articular This effect dimorphic, females more...