A5090208311- Lymphatic System and Diseases
- Diagnosis and Treatment of Venous Diseases
- Sympathectomy and Hyperhidrosis Treatments
- Reconstructive Surgery and Microvascular Techniques
- Myofascial pain diagnosis and treatment
- Peripheral Nerve Disorders
- Osteoarthritis Treatment and Mechanisms
- Reconstructive Facial Surgery Techniques
- Cell Adhesion Molecules Research
- Effects of Vibration on Health
- Proteoglycans and glycosaminoglycans research
- Connective tissue disorders research
- Pomegranate: compositions and health benefits
- Nerve Injury and Rehabilitation
- Exercise and Physiological Responses
- Body Contouring and Surgery
- Hemostasis and retained surgical items
- CNS Lymphoma Diagnosis and Treatment
- Blood properties and coagulation
- Natural product bioactivities and synthesis
- Anatomy and Medical Technology
- Dermatologic Treatments and Research
- Fibroblast Growth Factor Research
- Paleopathology and ancient diseases
- Protein Tyrosine Phosphatases
Okayama University
2014-2025
Sendai Kousei Hospital
2025
Macquarie University
2018-2020
Morpho (United States)
2018-2019
Kagawa Prefectural Central Hospital
2016-2017
Background Most lymphatic imaging examinations of the lower limb require intradermal or subcutaneous injection tracer material into foot to demonstrate vessels; however, no standard protocol exists, and single multiple injections are applied at different sites. Purpose To determine three-dimensional relationships between each group corresponding regional lymph nodes. Materials Methods A total 130 limbs (55 from men 75 women) 83 fresh human cadavers were studied. Lymphatic vessels first...
Background: The primary aim of this study was to determine the detailed anatomy lymphatics in lower extremity using fresh human cadavers with indocyanine green fluorescence lymphography. secondary apply anatomical results establish a new protocol for lymphography based on feasible allocations tracer injection sites. Methods: One hundred extremities from 53 were used study. authors injected solution subcutaneously at 19 points around foot along borderline between dorsum and planta according...
Abstract Most protocols for lymphatic imaging of the lower limb conventionally inject tracer materials only into interdigital space; however, recent studies indicate that there are four independent vessel groups (anteromedial, anterolateral, posteromedial, and posterolateral) in limb. Thus, three additional injection sites needed entire We aimed to validate a multiple designed protocol demonstrate its clinical benefits. Overall, 206 limbs undergoing indocyanine green fluorescent lymphography...
Objectives: The treatment of lower-extremity lymphedema, whether congenital or acquired, remains challenging. Long-term management aimed at reducing complications and maximizing quality life is essential. Compression stockings are crucial in this management; however, their application limited by patient experience (ease wear, texture, breathability, appearance). This highlights the need to evaluate alternative compression garments that maintain therapeutic efficacy while improving adherence....
Identification of the lymphatic system in cadavers is painstaking because vessels have very thin walls and are transparent. Selection appropriate contrast agents a key factor for successfully visualizing lymphatics. In this study, authors introduce new imaging technique mapping whole bodies fresh cadavers.Ten human were used study. The injected 0.1 ml indocyanine green fluorescence solution subcutaneously at multiple spots along watershed lines between territories hand foot regions. After...
The synovial fluids of patients with osteoarthritis (OA) contain elevated levels inflammatory cytokines, which induce the expression a disintegrin and metalloproteinase thrombospondin motifs (ADAMTS) matrix (MMP) in chondrocytes. Mechanical strain has varying effects on organisms depending strength, cycle, duration stressor; however, it is unclear under stimulation how mechanical act on. Here, we show that attenuates cytokine-induced matrix-degrading enzymes. Cyclic tensile (CTS), as...
Hyaluronan (HA) is an extracellular matrix (ECM) component of articular cartilage and has been used to treat patients with osteoarthritis (OA). A disintegrin metalloproteinases thrombospondin motifs (ADAMTSs) play important role in degradation OA. We have previously reported that ADAMTS4 ADAMTS9 were induced by cytokine stimulation. However, the effect HA on cytokine-inducible never investigated. Moreover, it unclear whether protects suppressing aggrecan degradation. Here, we examined...
<b>Background</b> The treatment of trauma to the lower extremities often carries a high risk complications. To best our knowledge, no study has been published regarding open lower-limb fractures using laser-assisted indocyanine green angiography (LA-ICG). Here we retrospectively evaluated LA-ICG–based therapeutic interventions and reported use LA-ICG its results in this application. <b>Patients Methods</b> Between January 2011 December 2015, total 23 cases with Gustilo grade IIIB were...
Background The purpose of this study was to evaluate the lymph function lower extremities and identify early symptoms dysfunction in secondary lymphedema by observing flow with indocyanine green (ICG) fluorescence lymphography (LG). Methods We retrospectively evaluated 108 limbs 54 female patients leg pelvic lymphadenectomy for gynecological carcinoma 14 7 controls without a history or radiotherapy. ICG injected into four points at distal part extremity. Lymph measuring proximal point where...
Indocyanine green (ICG) fluorescence lymphography (ICGLG) that can visualize the lymphatic vessel and its flow noninvasively dynamically was developed in 2007. It is frequently used to observe function pathway of vessels. ICGLG simple easy perform, it useful for understanding condition system real time. However, protocol not standardized. In addition, enhanced by an exercise load such as walking. Till now, there no report exercise-loaded ICGLG. Therefore, we aimed shorten examination time...
Abstract Most blood vessels contain elastin that provides the with resilience and flexibility necessary to control hemodynamics. Pathophysiological hemodynamic changes affect remodeling of elastic components, but little is known about their structural properties. The present study was designed elucidate, in detail, three-dimensional (3D) architecture delicate fibers small vessels, reveal architectural pattern a rat model. fine vascular components were observed by newly developed scanning...
As a new trial, we used interstitial computed tomography-lymphography (CT-LG) in 10 patients with lower extremity lymphedema (n=20 limbs) at stage 0, 1, 2, or 3 under the International Society of Lymphology (ISL) classification. In all cases, CT-LG, lymphoscintigraphy, and indocyanine green fluorescence-lymphography (ICG-LG) were performed. examination ascending level depicted lymphatic vessels, measured diameters vessels detected CT-LG conducted an image analysis dermal backflow lymph (DB)....
This study aimed to assess the use of 33 MHz ultra-high-frequency ultrasonography (33MHz-UHFUS) for evaluating axillary sweat glands with osmidrosis in comparison histological techniques. Axillary is a common problem Asian societies, and number size apocrine have strong relationship severity. Currently, there are no methods evaluate gland distribution non-invasively.In this study, 35 skin specimens from 10 fresh human cadavers without retrospective ultrasonographic images 20 patients were...
Abstract Pterygium colli is a congenital deformity associated with malformation syndromes. Various surgical procedures have been reported, but these advantages and disadvantages. The modified posterolateral approach has reported as new procedure for pterygium colli. However, there no confirmatory report. In this study, case of that was treated the reported. An 11-year-old girl Turner syndrome referred chief complaints web neck an abnormal hairline. selected. Hairy excessive skin excised at...
The lymphatic system is the area least investigated in field of anatomical science. major reason for this technical difficulty identifying lymphatics surrounding tissue post-mortem specimens. As a result, medical illustration masterpieces crafted by pioneer anatomists on basis cadaver dissections remain vital component current textbooks. Several innovative techniques were developed past to allow distinguish transparent structures from their surroundings and enable thorough investigation...
Secondary lymphoedema of the extremities is an important quality-of-life issue for patients who were treated their malignancies. Indocyanine green (ICG) fluorescent lymphography may be helpful assessing and planning lymphaticovenular anastomosis (LVA). The objective present clinical trial to confirm whether or not ICG using near-infrared monitoring camera useful indication LVA, identification lymphatic vessels before conduct confirmation patency site during surgery.This a phase III,...
Background: The hemodynamics of blood flowing from the anterior serratus to ribs has yet be analyzed in detail anterior/rib composite flaps. authors focused on new circulation, whereby slip arteries branched branch, off thoracodorsal artery and intercostal arteries, directly through interconnecting vessels (axial route). flaps developed a method for flap elevation. Methods: axial route was identified by performing macroscopic autopsies formalin perfusion-fixed cadavers involving...
Abstract Well‐vascularized tissue is required for successful reconstruction of a soft defect in the lumbar region. There are several options reconstruction; however, controversy exists regarding optimal technique. Here, we present case following tumor resection 75‐year‐old patient that was repaired using reverse‐supercharged, distally based latissimus dorsi flap. The size 15 × 12 cm 2 localized to An 11 7 ‐sized, flap designed cephalad muscle. After tunneled defect, vascular insufficiency...
Despite various options for the reconstruction of soft tissue defects in distal forearm, perforator-based propeller flap is rarely used. Here, we presented 2 cases forearm injuries that were repaired using recurrent branch anterior interosseous artery flap. Patients these 57 and 67 years age. Wounds resulting from farming machine injury pyogenic extensor tenosynovitis following cat bite wounds localized to dorsum hand. Defect dimensions 5 cm × 10 8 cm. The 12 7 21 4 sized was designed...
Indirect lymphatic system imaging is essential for diagnosing diseases. The basic methodology involves intradermal or subcutaneous injection of a contrast agent into the surrounding capillary, and flow identified using detector. Many agents that use near-infrared dye, including indocyanine green (ICG) fluorescent lymphography, are available. ICG rapidly spreading as convenient safe lymphedema diagnostic method, because it does not involve radiation exposure, equipment more compact than other...