A5011153603- Reconstructive Surgery and Microvascular Techniques
- Cleft Lip and Palate Research
- Head and Neck Surgical Oncology
- 3D Printing in Biomedical Research
- Organ Transplantation Techniques and Outcomes
- Trigeminal Neuralgia and Treatments
- Ear Surgery and Otitis Media
- Facial Nerve Paralysis Treatment and Research
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Oral and Maxillofacial Pathology
- Pediatric Hepatobiliary Diseases and Treatments
- Lung Cancer Treatments and Mutations
- Reconstructive Facial Surgery Techniques
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver physiology and pathology
- Rabies epidemiology and control
- Vascular Malformations and Hemangiomas
- Facial Trauma and Fracture Management
- Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Spinal Dysraphism and Malformations
- Korean Urban and Social Studies
- Inflammatory Biomarkers in Disease Prognosis
- Inflammatory Bowel Disease
Sapporo Higashi Tokushukai Hospital
2025
Okayama University
2000-2024
National Hospital Organization
2018-2021
Okayama Medical Center
2018-2021
May Institute
2018
Okayama University Hospital
2018
Kagawa Prefectural Central Hospital
2016
Tokyo Metropolitan Police Hospital
2008
The human DOC-2/DAB2 interactive protein (hDAB2IP) gene is a novel member of the Ras GTPase-activating family and has been demonstrated to be tumour-suppressor inactivated by methylation in several cancers. In this study, we analysed expression status hDAB2IP gastrointestinal tumours. promoter region was divided into two regions (m2a m2b) based on our previous report, determined bisulphite DNA sequencing gastric cancer cell lines. semiquantified real-time RT-PCR, results indicated that m2b...
Abstract Background Advanced surgical interventions are required to treat malignancies in the anterior skull base (ASB). This study investigates utility of endoscopic endonasal and transcranial surgery (EETS) using a high‐definition three‐dimensional exoscope as an alternative traditional microscopy. Methods Six patients with carcinomas varying histopathologies underwent employing EETS maneuver, which synchronized three distinct modalities: harvesting anterolateral thigh flap, initiation...
Portal vein branch embolization is often performed before hepatectomy to prevent postoperative liver failure. It is, however, still not clear how the embolized lobe shrinks and non-embolized proliferates in counterbalance. We investigated expression of positive negative regulators hepatocyte growth clarify mechanisms atrophy a rat portal ligation (PVL) model compared with partial (PH). A significant increase DNA synthesis within non-ligated reached peak at 36 h, delay 12 h as PH, while no...
<b>Background</b> The treatment of trauma to the lower extremities often carries a high risk complications. To best our knowledge, no study has been published regarding open lower-limb fractures using laser-assisted indocyanine green angiography (LA-ICG). Here we retrospectively evaluated LA-ICG–based therapeutic interventions and reported use LA-ICG its results in this application. <b>Patients Methods</b> Between January 2011 December 2015, total 23 cases with Gustilo grade IIIB were...
Abstract Background The pharyngeal flap (PF) is useful for reconstruction of soft palate defects, but effective arrangements PF various types defects are controversial. Here, we classify three and discuss the their functional prognosis. Methods Reconstruction was performed based on classification defects. Clinical details were collected, postoperative function analyzed. Results Eight patients included in study. defect sizes ranged from 25 (width) × 40 (depth) to 60 mm. Six underwent with...
Background In this article, we reviewed the training results of medical students using Microvascular Research Center Training Program (MRCP), and proposed an ideal microsurgical program for all individuals by analyzing who did not have any surgical experience. Methods As 2015, a total 29 completed MRCP. most recent 12 students, number trials performed each stage rats needed to complete were recorded. Additionally, measured operating time upon finishing 5 six after it became current program....
Raoultella planticola, a Gram-negative, aerobic bacillus commonly isolated from soil and water, rarely causes invasive infections in humans. Septic shock R. planticola after burn injury has not been previously reported. A 79-year-old male was admitted to the emergency intensive care unit extensive flame injury. He accidently caught fire while burning trash plunged into nearby tank filled with contaminated rainwater extinguish fire. The patient developed septic on day 10. blood culture...
Three-dimensional cell constructs comprising only tissue-specific cells and extracellular matrix secreted by them would be ideal transplants, but their fabrication in a aggregation manner without scaffolds relies on random self-aggregation, making the control of size shape difficult. In this study, we propose method to fabricate band-shaped tissues inducing self-aggregation sheets using developed technique (CAT). Acting as stoppers, silicone semicircular pillars were attached two positions...
With the advancement of tissue engineering technologies, implantable materials have been developed for use in facial plastic surgery, including auriculoplasty and rhinoplasty. Tissue-engineered cartilage comprising only cells cell-produced extracellular matrix is considered valuable as there no need to consider problems associated with scaffold absorption or immune responses commonly related conventional artificial materials. However, it exceedingly difficult produce large-sized complex...
The closure of palatal defects after tumor resection or irradiation is performed with either a prosthesis autogenous tissue; however, there are no clear criteria regarding selection the method. Thus, this study aimed to investigate real-world situation and problems using prostheses, examined patient opinion on how tissue improved their postoperative quality life (QOL).In 5 patients whose resulted from treatment for head neck cancer were closed prosthesis, palate was secondarily questionnaire...
The long-term changes in tissues implanted the oral cavity and pharynx after head neck reconstruction have not been fully evaluated. This study aimed to clarify morphological changes, durability, potential for secondary carcinogenesis such tissues. In our single-center study, rough 54 cases of intraoral pharyngeal skin mucosal flaps were evaluated more than 10 years flap transfer. addition, literature on development second carcinomas from was reviewed. mean follow-up period transferred 148...
In surgical treatment for longstanding facial paralysis, muscle transplantation is considered a useful and important method. To obtain spontaneous smile, the use of nerve healthy side as motor source better, but masseter allows prompt reinnervation powerful movement. However, in some patients whom used, separating masticatory movement commissure contraction difficult. Solutions such have not been determined.A 46-year-old female patient presented with complete paralysis after resection right...
An experiment was conducted to determine whether the oxygen and carbon dioxide gas tensions in liver tissue (PtO2 PtCO2, respectively) reflect state of microcirculation and/or metabolism ischemic liver. Subjects were divided into three groups: group 1, 30 min ischemia; 2, 60 3, four times intermittent 15 ischemia after every 10 reperfusion. PtO2, PtCO2 blood flow (TBF) measured by mass spectrometry, comparatively studied with serum GOT level as an indicator damage. Furthermore, time point at...