A5103193801- Renal Diseases and Glomerulopathies
- Advanced Radiotherapy Techniques
- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Urological Disorders and Treatments
- Medical Imaging Techniques and Applications
- Abdominal vascular conditions and treatments
- Meningioma and schwannoma management
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Brain Metastases and Treatment
- Abdominal Trauma and Injuries
- Hepatocellular Carcinoma Treatment and Prognosis
- Glioma Diagnosis and Treatment
- Chronic Kidney Disease and Diabetes
- Monoclonal and Polyclonal Antibodies Research
- Management of metastatic bone disease
- Vasculitis and related conditions
- Antimicrobial Resistance in Staphylococcus
- Colorectal Cancer Treatments and Studies
- Congenital Anomalies and Fetal Surgery
- Liver Disease and Transplantation
- Sports injuries and prevention
- Lymphoma Diagnosis and Treatment
- Cutaneous lymphoproliferative disorders research
- Cutaneous Melanoma Detection and Management
Sapporo Higashi Tokushukai Hospital
2024-2025
Asahikawa Medical University
2016-2023
Kitasato Institute Hospital
2020-2023
Kitasato University
2015-2023
University of Tsukuba
2004-2022
Kitasato University Medical Center
2017
Hiroshima Kyoritsu Hospital
2010-2016
Sendai Kousei Hospital
2006-2015
Japan Sport Council
2015
National Institute of Fitness and Sports in Kanoya
2015
ABSTRACT. Glomerular epithelial cells are primary pathogenic sites in focal segmental glomerulosclerosis (FGS) lesions. regarded as terminally differentiated that do not proliferate. These characteristics also noted for neurons and muscular cells, which major of mitochondrial DNA (mtDNA) mutation accumulation. Screening mtDNA mutations was performed with renal biopsy specimens from patients FGS IgA nephropathy (as subjects secondary control subjects). extracted kidney amplified appropriate...
BACKGROUND:Carbon dioxide (CO2) is believed to be the safest gas for laparoscopic surgery, which a standard procedure. We experienced severe cerebral infarction caused by paradoxical CO2 embolism during liver resection with injury of hepatic vessels despite absence right-to-left systemic shunt. CASE REPORT:A 60-year-old man was diagnosed hepatocellular carcinoma in right lobe secondary alcoholic disease. planned laparoscopy-assisted resection. During root vein injured. A 1.5-cm hole...
For gamma knife planning, 2.4-mm-slice MRIs are taken under rigid frame fixation, so tiny tumors become visible. This study evaluated differences in the numbers of brain metastases between conventional contrast-enhanced MRI (6 ± 1 mm slice thickness) before patient referral and for planning. The on 2 images were counted by at least oncologists. spoiled gradient-recalled echo obtained after 0.1 mmol/kg gadolinium administration using a 1.5-T system. Images from 1045 patients with an interval...
The efficacy of stereotactic radiosurgery (SRS) using Gamma Knife (GK) (Elekta, Tokyo) is well known. Recently, Automatic Brain Metastases Planning (ABMP) Element (BrainLAB, for a LINAC-based radiation system was commercially released. It covers multiple off-isocenter targets simultaneously inside multi-leaf collimator field and enables SRS / radiotherapy (SRT) with single group dynamic conformal multi-arcs (DCA) brain metastases. In this study, dose planning ABMP (ABMP-single isocenter DCA...
Abstract Few studies have investigated the relationship between blood type and trauma outcomes according to of injury. We conducted a retrospective multicenter observational study in twelve emergency hospitals Japan. Patients with isolated severe abdominal injury (abbreviated scale for abdomen ≥ 3 that other organs < 3) occurred 2008 2018 were divided into four groups type. The association mortality, ventilator-free days (VFD), total transfusion volume evaluated using univariate...
The objective of our study was to investigate the clinicopathological features currently ill‐defined subtype primary cutaneous T‐cell lymphoma unspecified type (CTCLU) with a cytotoxic phenotype and no Epstein–Barr virus (EBV) association. A series 27 patients CTCLU (median age 49 years; range 25–87 18 men) reviewed. Performance status scores above 1 (7%), clinical stages 2 (15%), B symptoms (26%), extracutaneous involvement (30%), fatal course within year diagnosis (19%) were observed...
Human hepatitis B virus (HBV) is well known as a cause of membranous nephropathy (MN). While the association HBV infection with MN strong, data regarding its other glomerular diseases are conflicting. Here, we report case focal segmental glomerulosclerosis (FSGS) infection. In this case, have found HBV-DNA in urinary podocytes by real-time PCR methods. After administration anti-viral therapy, FSGS improved, paralleling decreased level podocytes. The refractory induced could be effectively...
Inspiratory muscle fatigue (IMF) may limit exercise performance. A few studies have reported that IMF occurs after short-duration swimming exercise, but whether running can induce remains unclear. Intra-abdominal pressure is increased during through diaphragmatic activation to stabilize the spine movements of upper limbs. This along with inspiratory effort associated respirations exercise; thus, we hypothesized would IMF. To test this hypothesis, measured maximal (MIP) before and 400- 800-m...
CT scan and ultrasonography images revealed two small uniformly low-density hypoechoic lesions in the liver, respectively, 7 years after curative resection of rectal cancer, a 74-year-old man. The area liver including was segmentally resected. Two were histopathologically confirmed as early but active stage alveolar echinococcosis (AE) caused by accidental ingestion eggs fox tapeworm, Echinococcus multilocularis. This case is very unique rare, since hepatic AE cases have only accidentally...
Accurate diagnosis of lymphoma includes the assessment lineage‐specific markers. Hematopoietic and lymphoid tissues express PAX5 exclusively in pro‐B‐cell to mature B‐cell stages. However, some PAX5+ T‐cell lymphomas have been reported. We report three cases primary cutaneous CD30+ lymphoproliferative disorders (LPDs) with expression: one anaplastic large cell (ALCL) two lymphomatoid papulosis (LyP). The patients were 26 years old female, 75 65 male. In all cases, Hodgkin's...
Background Lenvatinib has been shown to be noninferior sorafenib regarding prognosis and recurrence rate in patients with unresectable hepatocellular carcinoma (HCC) who have not received prior systemic chemotherapy. In treated lenvatinib, 40% of cases achieved sufficient tumor reduction make potential surgery possible. However, the outcomes such are unknown. We report a successful case hepatic resection for recurrent HCC after lenvatinib treatment. Case summary A 69-year-old man underwent...
We assessed the geometric distortion of 1.5-Tesla (T) and 3.0-T magnetic resonance (MR) images with Leksell skull frame system using three types cranial quick fixation screws (QFSs) different materials—aluminum, aluminum tungsten tip, titanium—for fixation. Two kinds acrylic phantoms were placed on a screws, scanned computed tomography (CT), 1.5-T MR imaging imaging. The 3D coordinates for both strengths compared those CT. deviations measured at selected points (x = 50, 100 150; y 150)...
We used a proteomic approach to compare the differentially regulated protein expression profiles of cisplatin-naïve and cisplatin-resistant bladder cancer cell lines screen candidate molecules related cisplatin resistance. The line T24 was established by stepwise exposure cells up 40 μM cisplatin. performed comprehensive study in that included (T24) (T24CDDPR) means agarose two-dimensional gel electrophoresis followed analysis liquid chromatography tandem mass spectroscopy. identified 25...
Short bowel syndrome (SBS) resulting from acute aortic dissection (AAD)-induced visceral malperfusions leads to chronic intestinal failure (CIF), necessitating patients adopt home parenteral nutrition prevent malabsorption. Teduglutide (TED), a glucagon-like peptide-2 analog, is promising pharmacotherapy for rehabilitation that reduces support and improves the quality of life. Gastric mucosal necrosis, rare gastrointestinal disorder, had never been observed as an adverse event relevant this...
Fractionated stereotactic radiotherapy (SRT) is performed with a linear accelerator-based system such as Novalis. Recently, Gamma Knife Perfexion (PFX) featured the Extend relocatable fixation devices available for SRT. In this study, dosimetric results of these two modalities were compared from viewpoint conformity, heterogeneity and gradient in target covering. A total 14 patients skull base tumors treated Novalis intensity-modulated (IM)-SRT. Treatment was planned on an iPlan workstation....
Background: Uroplakins have been widely investigated as potential markers in patients with bladder cancer because these proteins are specific to the urothelium. However, role of uroplakin remains unknown. In this study, preoperative serum levels III were measured urothelial carcinoma urinary and examined for possible association clinicopathological features clinical outcomes. Materials Methods: This study included 52 at various stages 28 healthy controls. Uroplakin detected sera using an...
In treatment planning of Leksell Gamma Knife (LGK) radiosurgery, the skull geometry defined by generally dedicated scalar measurement has a crucial effect on dose calculation. The LGK Perfexion (PFX) unit is equipped with cone-shaped collimator divided into eight sectors, and its configuration entirely different from previous model C. Beam delivery PFX made combination but it also mechanically available one sector remaining seven blocked. Hence time using more likely to be affected...