- Acute Ischemic Stroke Management
- Gallbladder and Bile Duct Disorders
- Anesthesia and Neurotoxicity Research
- Head and Neck Cancer Studies
- Neurological Disease Mechanisms and Treatments
- Gastrointestinal disorders and treatments
- Neuroendocrine Tumor Research Advances
- Gastrointestinal Bleeding Diagnosis and Treatment
- RNA modifications and cancer
- Peptidase Inhibition and Analysis
- Lung Cancer Research Studies
- Venous Thromboembolism Diagnosis and Management
- Liver Disease Diagnosis and Treatment
- Diverticular Disease and Complications
- Neuroinflammation and Neurodegeneration Mechanisms
- Central Venous Catheters and Hemodialysis
- Lung Cancer Treatments and Mutations
- Abdominal vascular conditions and treatments
- Pancreatic and Hepatic Oncology Research
- Pediatric Hepatobiliary Diseases and Treatments
- Cancer-related cognitive impairment studies
- Cancer Diagnosis and Treatment
- Biliary and Gastrointestinal Fistulas
- Ferroptosis and cancer prognosis
- Neurological Disorders and Treatments
Peking University People's Hospital
2025
Peking University
2025
People's Liberation Army 401 Hospital
2025
First Affiliated Hospital of Dalian Medical University
2023-2024
Dalian Medical University
2023-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2023
Peking Union Medical College Hospital
2018-2023
Yangpu Hospital of Tongji University
2023
Soochow University
2011-2022
Tianjin Medical University
2004-2022
This study aimed to systematically investigate gene signatures for hepatoblastoma (HB) and identify potential biomarkers its diagnosis treatment.GSE131329 GSE81928 were obtained from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) between normal samples identified using Limma package in R. Then, similarity of network traits two sets was analyzed by weighted correlation analysis (WGCNA). Cytoscape used visualize select hub genes. PPI construed Cytoscape. GO...
Abstract Purpose To predict miscarriage outcome within 12 weeks of gestational age by evaluating values serum estradiol, progesterone and β-human chorionic gonadotropin (β-HCG) 9 gestation. Methods One hundred sixty-five women with singleton pregnancies were retrospectively studied. Estradiol, β-HCG levels measured at 5–6 gestation the measurements repeated 7–9 weeks. According to pregnancy gestation, 71 cases categorized into group, 94 group normal pregnancy. Each was further divided...
Catheter-related bloodstream infections represent one of the most prevalent complications in patients with peripherally inserted central venous catheters (PICCs). The application antibiotic lock therapy (ALT), particularly hematological malignancies, has not been well documented. We aim to share our experience on ALT for these and evaluate its effectiveness safety. All cases malignancies who had PICC from January 2018 October 2024 were retrospectively reviewed. Microbiologic data...
Abstract Immune checkpoint inhibitors (ICIs) have significantly improved the efficacy and prognosis of patients with non-small cell lung cancer (NSCLC). However, there remains a lack optimal predictive biomarkers for assessing response ICIs. This study aimed to evaluate peripheral inflammatory factors as potential NSCLC treated We retrospectively analyzed correlation between 124 driver gene-negative advanced who received first-line ICIs at our center from September 2018 June 2022....
Dipeptidyl peptidase-4 (DPP4) is one of the most potent mammalian serine proteases participated in pathogenesis subclinical atherosclerosis. Here we investigated whether plasma soluble form DPP4 associated with prevalence coronary artery disease (CAD) and without diabetes mellitus (DM). A cross-sectional study was conducted 496 aged 26-81 years (n = 362) 134) CAD. Plasma activity, high sensitive C-reactive protein (hs-CRP), low-density lipoprotein cholesterol (LDL-C), high-density levels...
The centralization of Artificial Intelligence (AI) poses significant challenges, including single points failure, inherent biases, data privacy concerns, and scalability issues. These problems are especially prevalent in closed-source large language models (LLMs), where user is collected used without transparency. To mitigate these issues, blockchain-based decentralized AI (DeAI) has emerged as a promising solution. DeAI combines the strengths both blockchain technologies to enhance...
Background/Aims Dual antiplatelet therapy has to be used for at least 1 month after placement of bare metal coronary stents and a minimum year drug eluting stents. Because the higher risk bleeding, guidelines strongly recommend delay elective surgery until dual is ended. However, no data are available regarding bleeding in patients on combined aspirin/clopidogrel undergoing surgical or high-risk endoscopic procedures. Methods We retrospectively analyzed medical reports therapy, who had...
Dual antiplatelet therapy has to be used for at least one month after placement of bare metal coronary stents and a minimum year drug eluting stents. Because the higher risk bleeding, guidelines strongly recommend delay elective surgery until dual is terminated. However, no data are available regarding bleeding in patients on combined aspirin/clopidogrel undergoing high-risk endoscopic procedures, such as emergency biliary sphincterotomy.We retrospectively analyzed medical reports who had...