A5011312716- Renal Diseases and Glomerulopathies
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Neuroendocrine Tumor Research Advances
- Dialysis and Renal Disease Management
- Breast Cancer Treatment Studies
- Advanced Radiotherapy Techniques
- Vasculitis and related conditions
- Chronic Kidney Disease and Diabetes
- Systemic Sclerosis and Related Diseases
- Effects of Radiation Exposure
- Ultrasound and Hyperthermia Applications
- Systemic Lupus Erythematosus Research
- Cancer-related molecular mechanisms research
- Radiomics and Machine Learning in Medical Imaging
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Ferroptosis and cancer prognosis
- Genomics, phytochemicals, and oxidative stress
- Cancer, Lipids, and Metabolism
- X-ray Diffraction in Crystallography
- Myasthenia Gravis and Thymoma
- Liver Disease Diagnosis and Treatment
Fudan University Shanghai Cancer Center
2012-2024
First Affiliated Hospital of Xi'an Jiaotong University
2015-2024
Soochow University
2023
Second Affiliated Hospital of Soochow University
2023
Shanghai Medical College of Fudan University
2012-2019
Duke University Hospital
2018
Duke Medical Center
2018
Xi'an Jiaotong University
2013-2015
Fudan University
2011-2013
University of North Carolina at Chapel Hill
2010-2013
The rapid increase in the prevalence of diabetes has resulted more cases diabetic kidney disease (DKD). Treatment with bone marrow mesenchymal stem cells (BMSCs) may represent an alternative strategy to manage DKD.HK-2 were treated 30 mM high glucose (HG). Bone MSC-derived exosomes (BMSC-exos) isolated and internalized into HK-2 cells. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide (MTT) lactate dehydrogenase (LDH) assays used measure viability cytotoxicity. secretion IL-1β...
MicroRNAs play a critical role in chemoresistance and are implicated various biological pathological processes of cells. The objective the present study was to explore miR‑133b its mechanism regulation cisplatin resistance tumor progression cisplatin‑resistant non‑small cell lung cancer (NSCLC) Reverse transcription‑quantitative polymerase chain reaction western blot assays lines A549/DPP H1299/DDP displayed reduced expression increased glutathione-S-transferase P1 (GSTP1) resistant cells...
Abstract Diabetic nephropathy (DN), a common cardiovascular disease, has been global health threat. MicroRNAs (miRNAs) have proposed to frequently participate in the occurrence and development of DN, however, role miR‐325‐3p DN remains uncharacterized. Our research aimed explore function mechanism DN. Bioinformatics analysis (Targetscan, http://www.targetscan.org ) wide range experiments including RT‐qPCR, CCK‐8 assay, western blot, luciferase reporter RNA immunoprecipitation (RIP) assays,...
Purpose/Objectives. Primary small cell esophageal carcinoma (SCEC) represents a rare and aggressive malignancy without any prospective clinical trial or established treatment strategy at present. Although previous studies have indicated similarities between SCEC lung cancer (SCLC) in terms of their manifestations, pathology, morphology, very little genetic information is available on this highly malignant tumor. At present, patients with are staged treated according to the guidelines for...
Podocyte loss in glomeruli is a fundamental event the pathogenesis of chronic kidney diseases. Currently, mitotic catastrophe (MC) has emerged as main cause podocyte loss. However, regulation MC podocytes yet to be elucidated. The current work aimed study role and mechanism p53 regulating using adriamycin (ADR)-induced nephropathy.
To research the distribution and quantitative changes of UT-A1, UT-B1, AQP5 in uremic skin tissue.34 cases patients (UP) 11 controls were recruited. Immunohistochemistry, immunofluorescence, RT-PCR, Western Blot used to identify proteins sweat glands.AQP5, UT-B1 expressed localized human basal lines, glands, ducts, both UP controls. Compared controls, mRNA abundance was significantly decreased (P < 0.01), and, with decrease eGFR, expression 0.05). By contrast, UT-A1 increased compared...
Previous genome-wide association studies have identified multiple susceptibility loci for IgA nephropathy (IgAN); however, validation of these findings is still needed.We performed a case-control study among 347 Chinese Han IgAN patients and 310 ethnicity-matched controls. Twenty-two single nucleotide polymorphisms (SNPs) were genotyped analysis was performed.We found three alleles in patients: the allele "C" rs2188404 CCDC132 gene by recessive model (odds ratio (OR), 1.65; 95% confidence...
To provide a profile of second malignant neoplasms (SMN) in patients with childhood primary brain tumour originating from neuroepithelial tissues latest data population-based study.Surveillance, Epidemiology, and End Results (SEER) database (1973-2007) was used to identify above-stated patients. SMN were further identified, standardised incidence ratios (SIRs) excess absolute risks (EARs) for risk-factor-decided subgroups calculated. Univariate multivariate analyses the association between...
Abstract Background Cardiac involvement frequently occurs in patients with renal light chain (AL) amyloidosis, which predisposes these to heart failure, arrhythmia, or infarction poor prognosis. Hypothesis Twelve‐lead electrocardiogram (ECG) parameters may be associated prognosis AL amyloidosis. Methods A retrospective single‐center cohort study was performed. Biopsy‐proven amyloidosis from January 2014 December 2018 at the First Affiliated Hospital of Xi'an Jiaotong University were...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Zhang Y, Xie L, Lu W, et al. LncRNA MIAT enhances systemic lupus erythematosus by upregulating CFHR5 expression via miR-222 degradation. Central European Journal of Immunology. 2021;46(1):17-26. doi:10.5114/ceji.2021.105242. APA Zhang, Y., Xie, L., Lu, W., Li, J., & Shao, Y. (2021). Immunology, 46(1), 17-26. https://doi.org/10.5114/ceji.2021.105242 Chicago Yali, Liyi Wanhong Jing Yan Yaozhong and Jiping Sun....
Treatment of idiopathic membranous nephropathy (IMN) remains a controversial issue. While clinical trials have shown that some immunosuppressants combined with glucocorticoid good efficacy on IMN patients. However, there is little data leflunomide (LEF) in treatment IMN.Records every patient biopsy-proven Department Nephrology, the First Affiliated Hospital, Xi'an Jiaotong University from January 2005 to December 2011 (n=194) were retrospectively analyzed. Patients nephrotic treated LEF plus...