A5018065939- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Advanced Radiotherapy Techniques
- Head and Neck Cancer Studies
- Lung Cancer Diagnosis and Treatment
- Effects of Radiation Exposure
- Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Endometrial and Cervical Cancer Treatments
- Sarcoma Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Colorectal Cancer Surgical Treatments
- Prostate Cancer Diagnosis and Treatment
- Management of metastatic bone disease
- Lung Cancer Treatments and Mutations
- Ultrasound and Hyperthermia Applications
- Breast Implant and Reconstruction
- Radiation Dose and Imaging
- Cancer and Skin Lesions
- Lymphoma Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Pleural and Pulmonary Diseases
- Cancer-related molecular mechanisms research
- Nonmelanoma Skin Cancer Studies
Liv Hospital
2021-2023
Istinye University
2016-2023
Istanbul University
2007-2019
University of North Carolina at Chapel Hill
2011-2012
Kocaeli Üniversitesi
2006-2009
Turkish Armed Forces
2006
Turkish Thoracic Society
2006
Metaplastic breast carcinoma (MBC) differs from classic invasive ductal carcinomas regarding incidence, pathogenesis, and prognosis. The purpose of this study was to compare patients with MBC clinicopathologic treatment-matched triple-negative (TNBC) in terms response treatment, progression, survival. Fifty-four 51 TNBC, who were treated at Istanbul University, Institute Oncology, between 1993 2014, included the study. After correctly matching 1 2 groups, they compared determine differences...
Long non-coding RNAs (lncRNAs) have been shown to be aberrantly expressed in head and neck cancer (HNC). The aim of the present study was evaluate plasma levels three lncRNA molecules (lincRNA-p21, GAS5, HOTAIR) treatment response HNC patients treated with radical chemoradiotherapy (CRT). Forty-one were enrolled study. Most had nasopharyngeal carcinoma (n = 27, 65.9 %) locally advanced disease. Blood drawn at baseline evaluation 4.5 months after therapy. lncRNAs measured by semiquantitative...
The purpose of this study was to evaluate ultrasound-guided surgery for palpable breast cancer by comparing the standard palpation-guided in terms extent healthy tissue resection, percentage tumor-free margins, and cosmetic outcomes. This a prospective, observational cohort conducted from January 2009 July 2011. Breast patients, diagnosed via biopsy, were operated guidance with either ultrasound or palpation. Patient demographics, tumor features, intraoperative findings, pathologic results,...
Aims and Background To report our experience of patients with primary glioblastoma multiforme young age by evaluating the characteristics, prognostic factors, treatment outcomes. Patients Methods Seventy (GBM) treated at department between 1996 2004 were studied. The male-female ratio was 2.6:1. median 53 (16-74). Sixty-eight (97%) operated on before radiotherapy 2 (3%) underwent only stereotactic biopsy. All received radiotherapy. Postoperative chemotherapy as an adjuvant to given 9 (12%)....
The purpose of this study was to determine the clinical significance vascular cell adhesion molecule-1 (VCAM-1) and epithelial molecule (EpCAM) in breast cancer (BC) patients. Ninety-six BC patients 30 age- sex-matched healthy controls were enrolled into study. Pretreatment serum markers determined by solid-phase sandwich (enzyme-linked immunosorbent assay (ELISA)). median age at diagnosis 48 years (range 29-80 years). Majority (71 %) had luminal subtype, 38.5 % metastatic disease....
Radiotherapy has an important role in the treatment of prostate cancer. Three-dimensional conformal radiation therapy (3D-CRT), intensity modulated (IMRT) and volumetric arc (VMAT) techniques are all applied for this purpose. However, risk secondary radiation-induced bladder cancer is significantly elevated irradiated patients compared surgery-only or watchful waiting groups. There also reports with low doses to normal tissues. This study was designed compare received volumes among 3D-CRT,...
To evaluate the efficacy of postoperative irradiation in renal cell carcinoma.Forty patients with localized carcinoma admitted to our hospital between 1986 and 1999 were evaluated. All initially treated radical nephrectomy. Postoperative radiotherapy was given 26 40 (65%). Fourteen (35%) received no adjuvant therapy. Median age 55 years (range, 20-70 years). Twenty-four (60%) men 16 (40%) women. Histopathological diagnosis all patients. N+ disease present 3 (7%). Stage I II 25 (63%) stage...
The purpose of this study was to determine the prevalence posttraumatic stress disorder (PTSD) in parents children with cancer. Five questionnaires were administered 104 parents, including a sociodemographic questionnaire, traumatic events check list, Structured Clinical Interview for DSM-IV PTSD and Major Depressive Disorder modules, self-rating instrument General Health Questionnaire-12. 34.6%. statistically significant tendency develop found female gender, better educational status, death...
Invasive micropapillary carcinoma (IMPC) of the breast is a highly aggressive and rare subtype cancer. In this study, we aimed to investigate differences between pure mixed IMPCs in terms clinicopathologic features, also analyze significance expressions ARID1A bcl-2 regarding prognosis. Sixty-nine consisting 21 48 type diagnosed at Pathology Department Istanbul Medical Faculty 2000 2011, who had complete follow-up data, were collected immunohistochemically with The median period was 94...
PurposeThere are no international guidelines for optimal needle insertion during interstitial intracavitary brachytherapy (IS-ICBT) cervical cancer. We aimed to investigate the clinical feasibility and added value of computed tomography (CT) guidance optimize in IS-ICBT using Utrecht applicator evaluate shifts.Methods MaterialsWe enrolled 24 patients who were treated with interstitial-brachytherapy. Two CT scans each performed every patient: (1) after without needles (CTpreneedle) (2)...
Blood-borne metastases to the kidneys from solid tumors have received little attention in medical literature because they usually occur a setting of advanced systemic disease, and renal involvement is elatively minor cause symptoms. Although frequency kidney cancer patients 7–13% large autopsy series, incidental discovery metastasis as first manifestation primary tumor very rare event. The most common malignancy involve bronchogenic carcinoma, followed by breast gastrointestinal cancers. In...
The purpose of this study was to evaluate the role combined modality treatment in patients with paediatric nasopharynx cancer (NPC). Forty-six NPC were retrospectively analysed. Forty-four 46 received treatment. Five-year overall survival and progression-free survivals 70% 72% for whole group, only three had loco-regional relapse. Complete remission obtained 18 45 (40%), (94% vs. 62% 19%, p = 0.0009) disease-free (93% 16%, 0.0002) significantly better complete responders when compared who...
Leiomyoma of the seminal vesicle is an extremely rare tumour. The diagnosis this entity important when it co-exists with prostatic carcinoma, since can simulate tumour extension from prostate or bladder cancer on MR imaging and lead to overstaging. In report, we describe a 74-year-old man leiomyoma that mimics co-existent T2-weighted imaging. To our knowledge, first description findings concurrent carcinoma.