A5004513032- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Colorectal and Anal Carcinomas
- Colorectal Cancer Treatments and Studies
- Neuroendocrine Tumor Research Advances
- Peptidase Inhibition and Analysis
- Pancreatic and Hepatic Oncology Research
- Sarcoma Diagnosis and Treatment
- Lung Cancer Research Studies
- Lymphoma Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Vascular Tumors and Angiosarcomas
- Cancer Treatment and Pharmacology
- Hepatocellular Carcinoma Treatment and Prognosis
- Multiple and Secondary Primary Cancers
- Cancer Genomics and Diagnostics
- Colorectal Cancer Surgical Treatments
- Endometrial and Cervical Cancer Treatments
- Head and Neck Cancer Studies
- Cervical Cancer and HPV Research
- Urinary and Genital Oncology Studies
- Neuroblastoma Research and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neutropenia and Cancer Infections
Istanbul University
2007-2022
Istanbul Bilim University
2014
Eskişehir Osmangazi Üniversitesi Tıp Fakültesi Hastanesi
2004
4227 Background: The aim of the study was to determine prognostic factors long-term survival after curative surgical treatment for pancreatic cancer. Methods: Between 1994 and 2000, resection with intent performed on 75 patients ductal adenocarcinoma admitted Department Surgery, Medical Faculty Istanbul. Clinical demographic features, postoperative adjuvant (5-fluorouracil continuous infusion external beam irradiation concomitantly), pathologic variables were analyzed. Results: A total...
Anemia is common in patients with cancer and a frequent complication of myelosuppressive chemotherapy. In this study, we investigated the incidence severity chemotherapy-induced anemia caused by most chemotherapy regimens, including new generation chemotherapeutic agents, used treatment major nonmyeloid malignancies adults. Five hundred fifty-two histologically proven carcinoma originating from breast (n = 165), lung 128), colon 75), ovary 84), malignant lymphoma 100) were included study....
This research evaluates the effectiveness of racquet mammoplasty versus conventional breast-conserving surgery (BCS) for upper-outer quadrant tumors, with an emphasis on oncological safety, cosmetic outcomes, and patient satisfaction. A retrospective analysis was conducted 268 individuals treated surgically breast tumors between August 2021 January 2024, 210 participants met inclusion criteria research. Information characteristics clinical parameters, such as gender, age, surgical method,...
A study was undertaken to analyze the extent of using complementary alternative medicine (CAM) and compare sociodemographic medical characteristics users non-users CAM in Turkish oncology patients. total 615 patients with cancer who attended ambulatory patient care units answered questionnaires. Medical information reviewed from chart data. Some 291 (47.3%) had used at least one type since time initial diagnosis. CAMs almost always consisted herbal agents (95%). Nettle (Urticae herba)...
The optimum duration between neoadjuvant radiochemotherapy and transmesorectal excision in locally advanced rectal cancer has not been defined yet. This randomized study was designed to compare the efficacy of four-week versus eight-week delay before surgery.One-hundred fifty-three patients with low- or mid-rectum adenocarcinoma were included this single center prospective trial. Patients assigned receive surgical treatment after either four weeks eight chemoradiotherapy. followed for local...
Colorectal cancer is predominantly a disease of the elderly population, but this unusual in patients 40 years age or under, and controversy persists as to prognosis subset patients. The aim study was determine clinicopathologic features their impact on survival colorectal aged younger, compare them with those older records 466 non-metastatic adenocarcinoma who were referred between 1991 1999 University Istanbul, Institute Oncology, following curative surgery retrospectively analysed. 84...
In Western literature, there are few studies investigating the predictors of early versus late recurrence after curative gastrectomy for gastric cancer. The current study analyzed (1) patients who died recurrent cancer and (2) prognostic factors, which can be applied to timing death from tumor recurrence. Of 492 underwent resection (R0) in Department Surgery, Medical Faculty Istanbul between 1994 2000, 142 were included into study. None had received postoperative adjuvant treatment. divided...
High BMI is a well-known risk factor for the development and recurrence of several solid tumours, including CRC. Obesity associated with increased levels vascular endothelial growth (VEGF). Bevacizumab main targeted therapy inhibiting tumour angiogenesis by blocking VEGF/VEGF receptor pathway. Elevated VEGF in obese patients might provoke resistance to anti-VEGF therapy. We evaluated efficacy bevacizumab on TTP among mCRC through stratifying them according their BMI. Patients who had been...
Skull base involvement of plasmacytoma is reported in a patient with light chain myeloma. A 39-year-old man was admitted after experiencing paresthesia on the left side face and arm, intermittent diplopia, hoarseness for 2 years. Cranial magnetic resonance imaging revealed large midline mass extending from middle posterior skull into upper two cervical vertebrae. An extramedullary associated multiple myeloma diagnosed biopsy laboratory investigations. The findings clinical features this rare...
<i>Background:</i> Osteosarcoma is a rare malignancy, and patients with this disease benefit from adjuvant chemotherapy. While cisplatin, anthracyclines ifosfamide are the most commonly used agents in treatment of osteosarcoma, search for best combination higher efficacy minimal toxicity continues. We planned to evaluate epirubicin combined cisplatin localized primary osteosarcoma. <i>Methods:</i> Patients nonmetastatic extremity osteosarcoma who were older than 15...
The aim of this study is to identify the impact various prognostic factors on survival in patients with recurrent carcinoma uterine cervix. Fifty-two who were treated platinum-based chemotherapy for or metastatic disease retrospectively evaluated. Twenty-seven (90%) had received pelvic radiation as primary treatment. Out 45 evaluable patients, two (4.4%) complete response (CR), three (6.7%) a continuous CR after additional surgical treatment and irradiation. Five (11.1%) partial (PR)....
AbstractThe taxanes are the most active new agents for squamous-cell carcinoma of head and neck (SCCHN) since discovery cisplatin. Our aim was to define therapeutic efficacy toxicity paclitaxel cisplatin combination therapy in patients with recurrent SCCHN. Patients locally or metastatic SCCHN were enrolled study. required be chemotherapy-naive, should have completed radiation at least 6 weeks prior enrollment. A World Health Organization (WHO) performance status less than 3 required....
Primary hepatocellular carcinoma (HCC) is common in Turkey and its prognosis poor. In the current study authors analyzed prognostic factors survival Turkish patients with inoperable HCC cirrhosis.Clinical demographic data of 91 consecutively admitted to authors' institute from 1988 2000 were reviewed. A univariate analysis was performed using Kaplan-Meier method identify predictors compared Mantel log-rank test. Independent correlated determined Cox regression analysis.Cirrhosis diagnosed...
Blood-borne metastases to the kidneys from solid tumors have received little attention in medical literature because they usually occur a setting of advanced systemic disease, and renal involvement is elatively minor cause symptoms. Although frequency kidney cancer patients 7–13% large autopsy series, incidental discovery metastasis as first manifestation primary tumor very rare event. The most common malignancy involve bronchogenic carcinoma, followed by breast gastrointestinal cancers. In...
Gastric carcinoma remains one of the leading causes cancer-related death in world. Clinical studies have revealed that approximately two thirds patients seek treatment for early recurrence within abdominal cavity. The aim this phase II study was to evaluate toxicity, feasibility, and efficacy adjuvant intraperitoneal chemotherapy (IPCT) with cisplatin, mitoxantrone, 5-fluorouracil (5-FU), folinic acid stage II-III gastric cancer. Patients III cancer aged between 15 70 years, after curative...
Best response rates have been achieved with three-drug regimens containing 5-FU in the treatment of advanced gastric cancer (AGC) and oral fluoropyrimidines are best alternatives as substitutes for infusional 5-FU. This study aimed to evaluate safety toxicity epirubicin, cisplatin, UFT (ECU regimen) AGC outpatients.Forty-one patients received plus leucovorin. Epirubicin 50 mg/m(2) cisplatin 60mg/m(2) were administered on Day 1. Three hundreds (300) mg/m(2)/day was leucovorin at a fixed dose...
The aim of this study was to investigate the outcomes and prognostic factors patients with metastatic gastrointestinal neuroendocrine tumor (mGI-NET) who were treated capecitabine temozolomide (CAPTEM) somatostatin receptor ligand (octreotide or lanreotide).Clinicopathological characteristics treatment 43 mGI-NET retrospectively evaluated. Overall survival (OS) progression-free (PFS) evaluated using Kaplan-Meier curve. Cox-regression analysis used assess variables.There 23 (53.5%) men 20...
Capecitabine has demonstrated high efficacy as first-line treatment for metastatic colorectal cancer (mCRC). In this non-randomized pilot study, we investigated the and safety of sequentially administered XELOX XELIRI regimens or reverse sequence in patients with advanced cancer.Entry criteria were histologically confirmed mCRC, ECOG performance status (PS) < =2 adequate bone marrow, renal hepatic function. All consecutively received followed by at disease progression vice versa.In...