A5053677698- Dementia and Cognitive Impairment Research
- Radiation Detection and Scintillator Technologies
- Nanowire Synthesis and Applications
- Alzheimer's disease research and treatments
- Digital Rights Management and Security
- Copyright and Intellectual Property
- Vehicle emissions and performance
- Semiconductor materials and interfaces
- Neurological Disease Mechanisms and Treatments
- Conducting polymers and applications
- Luminescence Properties of Advanced Materials
- Nuclear Physics and Applications
- Perovskite Materials and Applications
- Botulinum Toxin and Related Neurological Disorders
- Air Quality and Health Impacts
- Pregnancy and preeclampsia studies
- Neurological Disorders and Treatments
- Quantum Dots Synthesis And Properties
- Parkinson's Disease Mechanisms and Treatments
- Energy, Environment, and Transportation Policies
- Advanced Sensor and Energy Harvesting Materials
- Streptococcal Infections and Treatments
- Birth, Development, and Health
- Prenatal Substance Exposure Effects
- Advanced Steganography and Watermarking Techniques
Nanchang University
2024-2025
First Affiliated Hospital of Xi'an Jiaotong University
2009-2025
Sanya University
2025
Hainan University
2025
Weichai Power (China)
2022-2024
First Affiliated Hospital of Jiangxi Medical College
2024
Shanghai Jiao Tong University
2023-2024
Shandong Academy of Sciences
2024
Qilu University of Technology
2024
Georgetown University
2024
Abstract Background New therapies are urgently needed for Alzheimer’s disease (AD). Sodium oligomannate (GV-971) is a marine-derived oligosaccharide with novel proposed mechanism of action. The first phase 3 clinical trial GV-971 has been completed in China. Methods We conducted 3, double-blind, placebo-controlled participants mild-to-moderate AD to assess efficacy and safety. Participants were randomized placebo or (900 mg) 36 weeks. primary outcome was the drug-placebo difference change...
Abstract Plantar stress perception is highly desired in sports science and medical research, with the constraint of external power supply to impede portability flexibility daily life. Triboelectric nanogenerator (TENG) opens a new avenue for self‐power sensing; however, comprehensive sensing normal shear plantar remains elusive, let alone further exploration from mapping perspective. Here, TENG‐based self‐powered insole developed normal‐shear among four critical positions. At each position,...
A solution filling and drying method has been demonstrated to fabricate Si/PEDOT:PSS core/shell nanowire arrays for hybrid solar cells. The show excellent broadband anti-reflection, resulting cells absorb about 88% of AM 1.5G photons in the 300–1100 nm range. power conversion efficiency (PCE) cell reaches 6.35%, is primarily limited by direct indirect interfacial recombination charge carriers.
Background Plasma beta-amyloid (Aβ) are important biomarkers for Alzheimer’s disease and cognitive impairment (CI), but results controversial. It remains unclear whether hypertension modulates their relationship. This cross-sectional study investigates moderates the relationship between plasma Aβ (CI). Methods included 1488 subjects ≥ 40 years from rural areas of northwestern China. CI was defined as a Mini-Mental State Examination score lower than cutoff. Firstly, , 42 /Aβ were analyzed...
Grain size significantly affects rice yield and quality. Although several genes that regulate grain have been identified, their mechanisms remain unclear. In this study, we characterized the swg5 mutant, which has a smaller plant height, shorter panicles, grains compared to wild type (WT). MutMap resequencing gene knockout analysis identified SWG5 , encoding kinesin-13a protein, new allele of SRS3 positively regulates length weight. RNA sequencing analyses revealed is involved in diterpenoid...
Si/poly(3,4-ethylenedioxythiophene) (PEDOT) core/shell nanowire arrays have been prepared by chemical etching of Si nanowires followed vapor-phase polymerization PEDOT as hybrid photoanodes for photoelectrochemical water-splitting. The layer is employed a multi-functional coating to prevent photocorrosion nanowires, collect photogenerated holes and catalyze the water oxidation reaction. amino silane modified surface improves adhesion, resulting photoanode exhibits better photoresponse...
This paper presents a preliminary result about ultra-deep etched microstructures on 〈1 0 0〉 silicon wafer based metal assisted chemical etching (MaCE). Honeycomb hole arrays with 50 µm width were successfully etched, as deep 280 µm. The porous defects the patterned surface and lateral sidewall effectively suppressed by optimizing etchant solution. results in this indicate that can be vertically smooth sidewalls an solution containing ethanol, instead of conventional aqueous-based improved...
Controlling NOx and CO2 emissions from heavy-duty diesel vehicles (HDDVs) is receiving increasing attention. Accurate measurement of HDDV the prerequisite for emission control. Vehicle regulations srecommend using an analyzer, which expensive unsuitable to measure a large number in short time. The on-board diagnostics (OBD) data stream HDDVs provides great convenience calculating vehicle by providing engine fuel flow rate, sensor output, air mass flow. calculated based on OBD were validated...
Abstract It is now known that excess alcohol consumption during pregnancy can cause fetal syndrome to develop. However, it not whether ethanol exposure could directly affect angiogenesis in the embryo or being indirectly affected because of ethanol‐induced syndrome. Using chick yolk sac membrane (YSM) model, we demonstrated dramatically inhibited YSM 9‐day‐old embryos, a dose‐dependent manner. Likewise, anti‐angiogenesis effect be seen developing vessel plexus (at same extra‐embryonic...
Abstract It is now known that over‐consumption of caffeine by pregnant mothers could have detrimental effects on normal fetal development. However, it remains obscure how caffeine's harmful effect impacts directly or indirectly the developing embryo/fetus through damaging placenta In this study, we demonstrated morphological similarities between yolk sac and chorioallantoic membranes (CAM) chick embryos villi mammalian placenta. Using CAM as a model, found 5–15 µmol per egg exposure...
Autophagy is important for cell renewing its contribution to the degradation of bulk cytoplasm, long-lived proteins, and entire organelles role in embryonic development largely unknown. In our study, we investigated function autophagy gastrulation chick embryo using both vivo vitro approaches, especially EMT process, found that gene Atg7 was expressed on apical side ectoderm endoderm. Over-expression could enhance expression Atg8 E-cadherin, latter which a crucial marker process. We also...
Hybrid Si/poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) solar cells based on nanowire array structures with radial and axial junctions are prepared investigated. Compared to junction cells, exhibit much higher external quantum efficiency for long wavelength light due improved separation of photogenerated charge carriers, resulting in more than 10 times power conversion (PCE). By tuning the height hybrid investigating open circuit voltage decay, we identify that...
Most congenital heart defect (CHD) cases are attributed to nongenetic factors; however, the mechanisms underlying factor–induced CHDs elusive. Maternal diabetes is one of factors, and this study aimed determine whether impaired mitochondrial fusion contributes maternal diabetes–induced if activators, teriflunomide echinacoside, could reduce CHD incidence in diabetic pregnancy. We demonstrated diabetes-activated FoxO3a increases miR-140 miR-195, which turn represses Mfn1 Mfn2, leading defects...
Aims Two‐thirds of early pregnancy failures present with reduced trophoblast invasion, and SLIT 2/ ROBO 1 signalling is considered to play an important role in function during pregnancy. We investigated associated missed threatened miscarriage gestation. Methods results Human placenta samples were collected from women ( n = 25), 22) termination controls 32). Corresponding decreases beta human chorionic gonadotrophin (β‐hCG) levels shallow invasion observed patients miscarriage,...
Vascular factors and mitochondria dysfunction contribute to the pathogenesis of Alzheimer's disease (AD). DL-3-n-butylphthalide (NBP) has an effect in protecting improving microcirculation.The aim was investigate donepezil combined NBP therapy patients with mild-moderate AD.It a prospective cohort study. 92 AD were classified into alone group (n = 43) or 49) for 48 weeks. All evaluated Disease Assessment Scale-Cognitive subscale (ADAS-cog), Clinician's Interview-Based Impression Change plus...