- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Spatial Neglect and Hemispheric Dysfunction
- Alzheimer's disease research and treatments
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Effects and risks of endocrine disrupting chemicals
- Advanced Memory and Neural Computing
- Venous Thromboembolism Diagnosis and Management
- Diabetes Treatment and Management
- Transcranial Magnetic Stimulation Studies
- Eicosanoids and Hypertension Pharmacology
- Cardiac Fibrosis and Remodeling
- Intensive Care Unit Cognitive Disorders
- Ion Transport and Channel Regulation
- Neuroscience and Neural Engineering
- Nitric Oxide and Endothelin Effects
- Spectroscopy and Chemometric Analyses
- Cell Adhesion Molecules Research
- Diet, Metabolism, and Disease
- Adipokines, Inflammation, and Metabolic Diseases
- Lipid metabolism and disorders
- Fatty Acid Research and Health
- Dementia and Cognitive Impairment Research
- Optical Imaging and Spectroscopy Techniques
- Analog and Mixed-Signal Circuit Design
Capital Medical University
2024
Tianjin Medical University
2014-2024
Huazhong University of Science and Technology
2023
Ministry of Ecology and Environment
2023
Tongji University
2021
Tongji Hospital
2021
Shanghai Children's Medical Center
2020
Shandong Provincial Hospital
2016
Shandong University
2016
State Key Laboratory on Integrated Optoelectronics
2012-2015
Abstract Background New therapies are urgently needed for Alzheimer’s disease (AD). Sodium oligomannate (GV-971) is a marine-derived oligosaccharide with novel proposed mechanism of action. The first phase 3 clinical trial GV-971 has been completed in China. Methods We conducted 3, double-blind, placebo-controlled participants mild-to-moderate AD to assess efficacy and safety. Participants were randomized placebo or (900 mg) 36 weeks. primary outcome was the drug-placebo difference change...
Atrial fibrillation (AF) is the most common arrhythmia, and atrial fibrosis a pathological hallmark of structural remodeling in AF. Prostaglandin I
Previous studies have demonstrated that elevated admission and fasting glucose (FG) is associated with worse outcomes in patients acute myocardial infarction (AMI). However, the quantitative relationship between FG levels in-hospital mortality AMI remains unknown. The aim of study to assess prevalence hospitalized Chinese diabetes mellitus determine as well optimal level mellitus. A retrospective was carried out 1856 consecutive admitted for from 2002 2013. Clinical variables baseline...
An 8-channel, analog front-end chip for neural recording is presented in this paper. The consists of eight amplifiers with tunable bandwidth and gain, 4th-order Bessel switch capacitor filters, an 8-to-1 time-division multiplexer, a fully differential successive approximation (SAR) analog-to-digital converter (ADC), serial peripheral interface communication. amplifier presents programmable gain from 53 dB to 68 dB, low cut-off frequency 0.1 Hz several hundred Hz, 3.77 μV <sub...
Recent studies have shown that statins can influence insulin resistance (IR) in animal models and humans.1,2 However, the mechanism by which signaling pathway (ISP) remains obscure. It has been proposed pleiotropic effects of might be involved regulation IR. The phosphatidylinositol 3-kinase (PI3K)-Akt/protein kinase B (PKB) is main ISP. Insulin binding to receptor initiates PI3K-Akt phosphorylates tyrosine residue IR substrate proteins (IRSs) including IRS-1 IRS-2. Activation PI3K leads...
The symptoms of diabetes focal ischemia were more serious, but the concrete machanism is not very clear. For this we measure expression Acid - sensing ion channel 1a (ASIC1a) in ischemic cortex diabetic rats during different time, meanwhile observe protection fasudil after ischemia. 72 male wistar divided into 3 groups: ischemia, and interfere, 1h, 3h, 6h, 24h per group. high fat diet plus streptozotocin to model diabetic, thread cork establish models interfere group received 1mg/Kg...
Abstract Background: Postoperative thrombocytopenia with congenital heart disease (CHD) after percutaneous transcatheter closure (PTC) has seldom been reported. We sought to investigate the treatments, severity and causes of postoperative among patients CHD undergoing PTC.Methods: Six PTC in our department were included. Platelet count was measured at admission daily least for day 9.Results: Three had platelet counts below 30×10^9 /L while other two 50×10^9 /L. All achieved a stable count,...